Major histocompatibility complex, class I, F

mammalian protein found in Homo sapiens

Protein protein Q21120619

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Major histocompatibility complex, class I, F

Summary

Major histocompatibility complex, class I, F is a protein^[1].

Key Facts

Major histocompatibility complex, class I, F's instance of is recorded as protein^[2].
Major histocompatibility complex, class I, F's UniProt protein ID is recorded as P30511^[3].
Major histocompatibility complex, class I, F's part of is recorded as Immunoglobulin-like fold^[4].
Major histocompatibility complex, class I, F's part of is recorded as Immunoglobulin-like domain superfamily^[5].
Major histocompatibility complex, class I, F's part of is recorded as MHC classes I/II-like antigen recognition protein^[6].
Major histocompatibility complex, class I, F's part of is recorded as MHC class I-like antigen recognition-like superfamily^[7].
Major histocompatibility complex, class I, F's part of is recorded as MHC class I-like antigen recognition-like, protein family^[8].
Major histocompatibility complex, class I, F's part of is recorded as Immunoglobulin C1-set, protein family^[9].
Major histocompatibility complex, class I, F's part of is recorded as immunoglobulin-like domain, protein family^[10].
Major histocompatibility complex, class I, F's part of is recorded as Immunoglobulin/major histocompatibility complex, conserved site, protein family^[11].
Major histocompatibility complex, class I, F's part of is recorded as MHC class I alpha chain, alpha1 alpha2 domains, protein family^[12].
Major histocompatibility complex, class I, F's has part is recorded as immunoglobulin C1-set^[13].
Major histocompatibility complex, class I, F's has part is recorded as Immunoglobulin/major histocompatibility complex, conserved site^[14].
Major histocompatibility complex, class I, F's has part is recorded as immunoglobulin-like domain^[15].
Major histocompatibility complex, class I, F's has part is recorded as MHC class I alpha chain, alpha1 alpha2 domains^[16].
Major histocompatibility complex, class I, F's has part is recorded as MHC class I-like antigen recognition-like^[17].
Major histocompatibility complex, class I, F's RefSeq protein ID is recorded as NP_001091948^[18].
Major histocompatibility complex, class I, F's RefSeq protein ID is recorded as NP_001091949^[19].
Major histocompatibility complex, class I, F's RefSeq protein ID is recorded as NP_061823^[20].
Major histocompatibility complex, class I, F's RefSeq protein ID is recorded as XP_011512866^[21].
Major histocompatibility complex, class I, F's RefSeq protein ID is recorded as XP_016866299^[22].
Major histocompatibility complex, class I, F's RefSeq protein ID is recorded as XP_016866300^[23].
Major histocompatibility complex, class I, F's RefSeq protein ID is recorded as XP_016866301^[24].
Major histocompatibility complex, class I, F's RefSeq protein ID is recorded as XP_016866302^[25].
Major histocompatibility complex, class I, F's RefSeq protein ID is recorded as XP_016866303^[26].

⭐ Popularity Graph

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Quick Facts

Instance of protein

Part of Immunoglobulin-like fold, Immunoglobulin-like domain superfamily, MHC classes I/II-like antigen recognition protein, MHC class I-like antigen recognition-like superfamily, MHC class I-like antigen recognition-like, protein family, Immunoglobulin C1-set, protein family, immunoglobulin-like domain, protein family, Immunoglobulin/major histocompatibility complex, conserved site, protein family, MHC class I alpha chain, alpha1 alpha2 domains, protein family

Properties

Biological process antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, interferon-gamma-mediated signaling pathway, immune system process, antigen processing and presentation of peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, type I interferon signaling pathway, regulation of immune response, positive regulation of T cell mediated cytotoxicity, antigen processing and presentation of peptide antigen via MHC class I, antigen processing and presentation of endogenous peptide antigen via MHC class Ib, immune response, positive regulation of T cell mediated cytotoxicity, antigen processing and presentation of endogenous peptide antigen via MHC class Ib, antigen processing and presentation of exogenous peptide antigen via MHC class Ib, antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent, negative regulation of T cell cytokine production, negative regulation of natural killer cell cytokine production, positive regulation of natural killer cell cytokine production, negative regulation of natural killer cell degranulation, positive regulation of natural killer cell degranulation, negative regulation of natural killer cell mediated cytotoxicity, negative regulation of neuron death

Cell component integral component of membrane, phagocytic vesicle membrane, early endosome membrane, membrane, Golgi membrane, plasma membrane, cell surface, endoplasmic reticulum, MHC class I protein complex, ER to Golgi transport vesicle membrane, integral component of lumenal side of endoplasmic reticulum membrane, recycling endosome membrane, membrane, Golgi membrane, extracellular space, lysosome, lysosomal membrane, endosome, plasma membrane, external side of plasma membrane, early endosome membrane, MHC class Ib protein complex

Encoded by HLA-F

Found in taxon Homo sapiens

Has part(s) immunoglobulin C1-set, Immunoglobulin/major histocompatibility complex, conserved site, immunoglobulin-like domain, MHC class I alpha chain, alpha1 alpha2 domains, MHC class I-like antigen recognition-like

Imported from wholeness_audit_2026-05-02

Molecular function TAP2 binding, TAP1 binding, signaling receptor binding, peptide antigen binding, protein binding, beta-2-microglobulin binding, peptide antigen binding, 14-3-3 protein binding

External References (3)

Ensembl protein id ENSP00000259951, ENSP00000334263, ENSP00000351977, ENSP00000366044, ENSP00000366057, ENSP00000373007, ENSP00000393535, ENSP00000397376, ENSP00000399835, ENSP00000390887, ENSP00000373008, ENSP00000448260, ENSP00000399120, ENSP00000486947, ENSP00000373121, ENSP00000407836, ENSP00000399043, ENSP00000373123, ENSP00000388133, ENSP00000402853, ENSP00000400112, ENSP00000414905, ENSP00000414318, ENSP00000387786, ENSP00000392251, ENSP00000415017, ENSP00000409934, ENSP00000408540, ENSP00000396776, ENSP00000415401, ENSP00000486309, ENSP00000405190, ENSP00000450119, ENSP00000398913, ENSP00000395853, ENSP00000397705, ENSP00000366040, ENSP00000483269, ENSP00000414500, ENSP00000447401, ENSP00000416426, ENSP00000404395, ENSP00000405198, ENSP00000345828, ENSP00000482177, ENSP00000450300, ENSP00000389555, ENSP00000447228, ENSP00000412140, ENSP00000400299

Refseq protein id NP_001091948, NP_001091949, NP_061823, XP_011512866, XP_016866299, XP_016866300, XP_016866301, XP_016866302, XP_016866303, XP_016866304

Uniprot protein id P30511

🏷️ Also known as

en CDA12 en HLA class I histocompatibility antigen, alpha chain F en HLA-F en HLA F antigen en leukocyte antigen F en Major histocompatibility complex, class I, F en MHC class I antigen F

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Major histocompatibility complex, class I, F — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Major histocompatibility complex, class I, F — UniProt protein ID (P352): P30511. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Major histocompatibility complex, class I, F — part of (P361): Immunoglobulin-like fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Major histocompatibility complex, class I, F — part of (P361): Immunoglobulin-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Major histocompatibility complex, class I, F — part of (P361): MHC classes I/II-like antigen recognition protein. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Major histocompatibility complex, class I, F — part of (P361): MHC class I-like antigen recognition-like superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Major histocompatibility complex, class I, F — part of (P361): MHC class I-like antigen recognition-like, protein family. wikidata.org.
[9] ↑ Major histocompatibility complex, class I, F — part of (P361): Immunoglobulin C1-set, protein family. wikidata.org.
[10] ↑ Major histocompatibility complex, class I, F — part of (P361): immunoglobulin-like domain, protein family. wikidata.org.
[11] ↑ Major histocompatibility complex, class I, F — part of (P361): Immunoglobulin/major histocompatibility complex, conserved site, protein family. wikidata.org.
[12] ↑ Major histocompatibility complex, class I, F — part of (P361): MHC class I alpha chain, alpha1 alpha2 domains, protein family. wikidata.org.
[13] ↑ Major histocompatibility complex, class I, F — has part(s) (P527): immunoglobulin C1-set. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Major histocompatibility complex, class I, F — has part(s) (P527): Immunoglobulin/major histocompatibility complex, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Major histocompatibility complex, class I, F — has part(s) (P527): immunoglobulin-like domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Major histocompatibility complex, class I, F — has part(s) (P527): MHC class I alpha chain, alpha1 alpha2 domains. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Major histocompatibility complex, class I, F — has part(s) (P527): MHC class I-like antigen recognition-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Major histocompatibility complex, class I, F — RefSeq protein ID (P637): NP_001091948. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ Major histocompatibility complex, class I, F — RefSeq protein ID (P637): NP_001091949. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ Major histocompatibility complex, class I, F — RefSeq protein ID (P637): NP_061823. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Major histocompatibility complex, class I, F — RefSeq protein ID (P637): XP_011512866. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Major histocompatibility complex, class I, F — RefSeq protein ID (P637): XP_016866299. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ Major histocompatibility complex, class I, F — RefSeq protein ID (P637): XP_016866300. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ Major histocompatibility complex, class I, F — RefSeq protein ID (P637): XP_016866301. Q20641742. Retrieved 2020-05-30. wikidata.org.
[25] ↑ Major histocompatibility complex, class I, F — RefSeq protein ID (P637): XP_016866302. Q20641742. Retrieved 2020-05-30. wikidata.org.
[26] ↑ Major histocompatibility complex, class I, F — RefSeq protein ID (P637): XP_016866303. Q20641742. Retrieved 2020-05-30. wikidata.org.

Class ancestry

[1] ↑ Major histocompatibility complex, class I, F is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Major histocompatibility complex, class I, F. Retrieved May 3, 2026, from https://4ort.xyz/entity/major-histocompatibility-complex-class-i-f

MLA

“Major histocompatibility complex, class I, F.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/major-histocompatibility-complex-class-i-f.

BibTeX

@misc{4ortxyz_major-histocompatibility-complex-class-i-f_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Major histocompatibility complex, class I, F}}, year = {2026}, url = {https://4ort.xyz/entity/major-histocompatibility-complex-class-i-f}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Major histocompatibility complex, class I, F — https://4ort.xyz/entity/major-histocompatibility-complex-class-i-f (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/major-histocompatibility-complex-class-i-f · Last refreshed: May 3, 2026