MAD2 mitotic arrest deficient-like 2

mammalian protein found in Mus musculus

Protein protein Q21988271

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Summary

MAD2 mitotic arrest deficient-like 2 is a protein^[1].

Key Facts

MAD2 mitotic arrest deficient-like 2's instance of is recorded as protein^[2].
MAD2 mitotic arrest deficient-like 2's subclass of is recorded as protein^[3].
MAD2 mitotic arrest deficient-like 2's UniProt protein ID is recorded as Q9D752^[4].
MAD2 mitotic arrest deficient-like 2's part of is recorded as HORMA domain superfamily^[5].
MAD2 mitotic arrest deficient-like 2's part of is recorded as HORMA domain, protein family^[6].
MAD2 mitotic arrest deficient-like 2's has part is recorded as HORMA domain^[7].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as NP_001292349^[8].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as NP_082261^[9].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_006539246^[10].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_006539249^[11].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_006539250^[12].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_006539251^[13].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_006539252^[14].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_030109648^[15].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_030109649^[16].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_030109650^[17].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_030109651^[18].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_030109652^[19].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_030109653^[20].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_030109654^[21].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_030109655^[22].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_030109656^[23].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_030109657^[24].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_030109658^[25].
MAD2 mitotic arrest deficient-like 2's RefSeq protein ID is recorded as XP_030109659^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of HORMA domain superfamily, HORMA domain, protein family

Properties

Biological process DNA damage response, signal transduction resulting in transcription, regulation of transcription, DNA-templated, negative regulation of protein catabolic process, actin filament organization, negative regulation of cell-cell adhesion mediated by cadherin, negative regulation of transcription by competitive promoter binding, negative regulation of transcription by RNA polymerase II, negative regulation of DNA-binding transcription factor activity, transcription, DNA-templated, positive regulation of peptidyl-serine phosphorylation, cellular response to DNA damage stimulus, cell division, positive regulation of transcription, DNA-templated, negative regulation of transcription regulatory region DNA binding, double-strand break repair, regulation of cell growth, cell cycle, negative regulation of canonical Wnt signaling pathway, negative regulation of epithelial to mesenchymal transition, negative regulation of ubiquitin protein ligase activity, DNA repair, positive regulation of isotype switching, negative regulation of double-strand break repair via homologous recombination, positive regulation of double-strand break repair via nonhomologous end joining, positive regulation of isotype switching, negative regulation of double-strand break repair via homologous recombination, positive regulation of double-strand break repair via nonhomologous end joining

Cell component cytoplasm, spindle, zeta DNA polymerase complex, anaphase-promoting complex, cytoskeleton, nucleus, nucleolus, cytosol, chromosome, zeta DNA polymerase complex

Encoded by Mad2l2

Found in taxon house mouse

Has part(s) HORMA domain

Imported from wholeness_audit_2026-05-02

Molecular function JUN kinase binding

External References (4)

Ensembl protein id ENSMUSP00000030860, ENSMUSP00000081146, ENSMUSP00000101332, ENSMUSP00000120481, ENSMUSP00000122774

Pdb structure id 4FJO

Refseq protein id NP_001292349, NP_082261, XP_006539246, XP_006539249, XP_006539250, XP_006539251, XP_006539252, XP_030109648, XP_030109649, XP_030109650, XP_030109651, XP_030109652, XP_030109653, XP_030109654, XP_030109655, XP_030109656, XP_030109657, XP_030109658, XP_030109659

Uniprot protein id Q9D752

🏷️ Also known as

en Mad2l2 en MAD2-like protein 2 en MAD2 mitotic arrest deficient-like 2 en mitotic arrest deficient 2-like protein 2 en mitotic spindle assembly checkpoint protein MAD2B

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ MAD2 mitotic arrest deficient-like 2 — instance of (P31): protein. UniProt. Retrieved 2022-05-25. wikidata.org.
[3] ↑ MAD2 mitotic arrest deficient-like 2 — subclass of (P279): protein. UniProt. Retrieved 2017-01-19. wikidata.org.
[4] ↑ MAD2 mitotic arrest deficient-like 2 — UniProt protein ID (P352): Q9D752. UniProt. Retrieved 2022-05-25. wikidata.org.
[5] ↑ MAD2 mitotic arrest deficient-like 2 — part of (P361): HORMA domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ MAD2 mitotic arrest deficient-like 2 — part of (P361): HORMA domain, protein family. wikidata.org.
[7] ↑ MAD2 mitotic arrest deficient-like 2 — has part(s) (P527): HORMA domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): NP_001292349. Q20641742. Retrieved 2022-03-20. wikidata.org.
[9] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): NP_082261. Q20641742. Retrieved 2022-03-20. wikidata.org.
[10] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_006539246. Q20641742. Retrieved 2022-03-20. wikidata.org.
[11] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_006539249. Q20641742. Retrieved 2022-03-20. wikidata.org.
[12] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_006539250. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_006539251. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_006539252. Q20641742. Retrieved 2022-03-20. wikidata.org.
[15] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_030109648. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_030109649. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_030109650. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_030109651. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_030109652. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_030109653. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_030109654. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_030109655. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_030109656. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_030109657. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_030109658. Q20641742. Retrieved 2022-03-20. wikidata.org.
[26] ↑ MAD2 mitotic arrest deficient-like 2 — RefSeq protein ID (P637): XP_030109659. Q20641742. Retrieved 2022-03-20. wikidata.org.

Class ancestry

[1] ↑ MAD2 mitotic arrest deficient-like 2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). MAD2 mitotic arrest deficient-like 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/mad2-mitotic-arrest-deficient-like-2

MLA

“MAD2 mitotic arrest deficient-like 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/mad2-mitotic-arrest-deficient-like-2.

BibTeX

@misc{4ortxyz_mad2-mitotic-arrest-deficient-like-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{MAD2 mitotic arrest deficient-like 2}}, year = {2026}, url = {https://4ort.xyz/entity/mad2-mitotic-arrest-deficient-like-2}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): MAD2 mitotic arrest deficient-like 2 — https://4ort.xyz/entity/mad2-mitotic-arrest-deficient-like-2 (retrieved 2026-05-03)

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