Lysine (K)-specific demethylase 3A

mammalian protein found in Mus musculus

Protein protein Q21987126

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Summary

Lysine (K)-specific demethylase 3A is a protein^[1].

Key Facts

Lysine (K)-specific demethylase 3A's instance of is recorded as protein^[2].
Lysine (K)-specific demethylase 3A's subclass of is recorded as protein^[3].
Lysine (K)-specific demethylase 3A's UniProt protein ID is recorded as Q6PCM1^[4].
Lysine (K)-specific demethylase 3A's part of is recorded as JmjC domain, protein family^[5].
Lysine (K)-specific demethylase 3A's has part is recorded as JmjC domain^[6].
Lysine (K)-specific demethylase 3A's RefSeq protein ID is recorded as NP_001033784^[7].
Lysine (K)-specific demethylase 3A's RefSeq protein ID is recorded as NP_766589^[8].
Lysine (K)-specific demethylase 3A's RefSeq protein ID is recorded as NP_001349129^[9].
Lysine (K)-specific demethylase 3A's RefSeq protein ID is recorded as NP_001349130^[10].
Lysine (K)-specific demethylase 3A's RefSeq protein ID is recorded as XP_030110909^[11].
Lysine (K)-specific demethylase 3A's RefSeq protein ID is recorded as XP_030110910^[12].
Lysine (K)-specific demethylase 3A's RefSeq protein ID is recorded as XP_036021613^[13].
Lysine (K)-specific demethylase 3A's molecular function is recorded as iron ion binding^[14].
Lysine (K)-specific demethylase 3A's molecular function is recorded as DNA-binding transcription factor activity^[15].
Lysine (K)-specific demethylase 3A's molecular function is recorded as dioxygenase activity^[16].
Lysine (K)-specific demethylase 3A's molecular function is recorded as transcription cis-regulatory region binding^[17].
Lysine (K)-specific demethylase 3A's molecular function is recorded as metal ion binding^[18].
Lysine (K)-specific demethylase 3A's molecular function is recorded as protein binding^[19].
Lysine (K)-specific demethylase 3A's molecular function is recorded as androgen receptor binding^[20].
Lysine (K)-specific demethylase 3A's molecular function is recorded as oxidoreductase activity^[21].
Lysine (K)-specific demethylase 3A's molecular function is recorded as chromatin DNA binding^[22].
Lysine (K)-specific demethylase 3A's molecular function is recorded as histone H3-methyl-lysine-9 demethylase activity^[23].
Lysine (K)-specific demethylase 3A's molecular function is recorded as RNA polymerase II core promoter sequence-specific DNA binding^[24].
Lysine (K)-specific demethylase 3A's molecular function is recorded as transcription cis-regulatory region binding^[25].
Lysine (K)-specific demethylase 3A's cell component is recorded as cytoplasm^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of JmjC domain, protein family

Properties

Biological process androgen receptor signaling pathway, cell differentiation, regulation of transcription, DNA-templated, histone H3-K9 demethylation, histone H3-K9 dimethylation, regulation of stem cell differentiation, regulation of stem cell population maintenance, transcription, DNA-templated, positive regulation of transcription, DNA-templated, spermatogenesis, hormone-mediated signaling pathway, negative regulation of histone H3-K9 methylation, regulation of gene expression, formaldehyde biosynthetic process, spermatid nucleus elongation, positive regulation of transcription by RNA polymerase II, cellular response to leukemia inhibitory factor, chromatin organization, positive regulation of gene expression, histone H3-K9 demethylation, positive regulation of cold-induced thermogenesis

Cell component cytoplasm, nucleoplasm, nucleus, chromatin, nucleus

Encoded by Kdm3a

Found in taxon house mouse

Has part(s) JmjC domain

Imported from wholeness_audit_2026-05-02

Molecular function iron ion binding, DNA-binding transcription factor activity, dioxygenase activity, transcription cis-regulatory region binding, metal ion binding, protein binding, androgen receptor binding, oxidoreductase activity, chromatin DNA binding, histone H3-methyl-lysine-9 demethylase activity, RNA polymerase II core promoter sequence-specific DNA binding, transcription cis-regulatory region binding

External References (3)

Ensembl protein id ENSMUSP00000065716, ENSMUSP00000128789, ENSMUSP00000145959, ENSMUSP00000145719, ENSMUSP00000145992

Refseq protein id NP_001033784, NP_766589, NP_001349129, NP_001349130, XP_030110909, XP_030110910, XP_036021613

Uniprot protein id Q6PCM1

🏷️ Also known as

en [histone H3]-dimethyl-L-lysine(9) demethylase 3A en jmjC domain-containing histone demethylation protein 2A en jumonji domain-containing protein 1A en Kdm3a en Lysine (K)-specific demethylase 3A en lysine-specific demethylase 3A en testis specific gene A nl Lysine

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Lysine (K)-specific demethylase 3A — instance of (P31): protein. UniProt. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Lysine (K)-specific demethylase 3A — subclass of (P279): protein. UniProt. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Lysine (K)-specific demethylase 3A — UniProt protein ID (P352): Q6PCM1. UniProt. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Lysine (K)-specific demethylase 3A — part of (P361): JmjC domain, protein family. wikidata.org.
[6] ↑ Lysine (K)-specific demethylase 3A — has part(s) (P527): JmjC domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Lysine (K)-specific demethylase 3A — RefSeq protein ID (P637): NP_001033784. Q20641742. Retrieved 2022-03-20. wikidata.org.
[8] ↑ Lysine (K)-specific demethylase 3A — RefSeq protein ID (P637): NP_766589. Q20641742. Retrieved 2022-03-20. wikidata.org.
[9] ↑ Lysine (K)-specific demethylase 3A — RefSeq protein ID (P637): NP_001349129. Q20641742. Retrieved 2022-03-20. wikidata.org.
[10] ↑ Lysine (K)-specific demethylase 3A — RefSeq protein ID (P637): NP_001349130. Q20641742. Retrieved 2022-03-20. wikidata.org.
[11] ↑ Lysine (K)-specific demethylase 3A — RefSeq protein ID (P637): XP_030110909. Q20641742. Retrieved 2022-03-20. wikidata.org.
[12] ↑ Lysine (K)-specific demethylase 3A — RefSeq protein ID (P637): XP_030110910. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ Lysine (K)-specific demethylase 3A — RefSeq protein ID (P637): XP_036021613. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ Lysine (K)-specific demethylase 3A — molecular function (P680): iron ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Lysine (K)-specific demethylase 3A — molecular function (P680): DNA-binding transcription factor activity. The histone demethylase, Jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Lysine (K)-specific demethylase 3A — molecular function (P680): dioxygenase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Lysine (K)-specific demethylase 3A — molecular function (P680): transcription cis-regulatory region binding. The histone demethylase, Jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Lysine (K)-specific demethylase 3A — molecular function (P680): metal ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Lysine (K)-specific demethylase 3A — molecular function (P680): protein binding. The histone demethylase, Jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Lysine (K)-specific demethylase 3A — molecular function (P680): androgen receptor binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Lysine (K)-specific demethylase 3A — molecular function (P680): oxidoreductase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Lysine (K)-specific demethylase 3A — molecular function (P680): chromatin DNA binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Lysine (K)-specific demethylase 3A — molecular function (P680): histone H3-methyl-lysine-9 demethylase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Lysine (K)-specific demethylase 3A — molecular function (P680): RNA polymerase II core promoter sequence-specific DNA binding. Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Lysine (K)-specific demethylase 3A — molecular function (P680): transcription cis-regulatory region binding. The histone demethylase, Jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Lysine (K)-specific demethylase 3A — cell component (P681): cytoplasm. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Lysine (K)-specific demethylase 3A is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

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BibTeX

@misc{4ortxyz_lysine-k-specific-demethylase-3a_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Lysine (K)-specific demethylase 3A}}, year = {2026}, url = {https://4ort.xyz/entity/lysine-k-specific-demethylase-3a}, note = {Accessed: 2026-05-03}}

LLM prompt

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