Lymphoid enhancer binding factor 1

mammalian protein found in Mus musculus

Protein protein Q21498209

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Lymphoid enhancer binding factor 1

Summary

Lymphoid enhancer binding factor 1 is a protein^[1].

Key Facts

Lymphoid enhancer binding factor 1's instance of is recorded as protein^[2].
Lymphoid enhancer binding factor 1's subclass of is recorded as protein^[3].
Lymphoid enhancer binding factor 1's UniProt protein ID is recorded as P27782^[4].
Lymphoid enhancer binding factor 1's part of is recorded as Catenin binding domain superfamily^[5].
Lymphoid enhancer binding factor 1's part of is recorded as High mobility group box domain superfamily^[6].
Lymphoid enhancer binding factor 1's part of is recorded as lymphoid enhancer-binding factor 1^[7].
Lymphoid enhancer binding factor 1's part of is recorded as High mobility group box domain, protein family^[8].
Lymphoid enhancer binding factor 1's part of is recorded as CTNNB1 binding, N-teminal, protein family^[9].
Lymphoid enhancer binding factor 1's has part is recorded as CTNNB1 binding, N-teminal^[10].
Lymphoid enhancer binding factor 1's has part is recorded as High mobility group box domain^[11].
Lymphoid enhancer binding factor 1's RefSeq protein ID is recorded as NP_001263331^[12].
Lymphoid enhancer binding factor 1's RefSeq protein ID is recorded as NP_001263332^[13].
Lymphoid enhancer binding factor 1's RefSeq protein ID is recorded as NP_034833^[14].
Lymphoid enhancer binding factor 1's RefSeq protein ID is recorded as XP_006501133^[15].
Lymphoid enhancer binding factor 1's RefSeq protein ID is recorded as XP_030108300^[16].
Lymphoid enhancer binding factor 1's RefSeq protein ID is recorded as NP_001365988^[17].
Lymphoid enhancer binding factor 1's RefSeq protein ID is recorded as NP_001365989^[18].
Lymphoid enhancer binding factor 1's RefSeq protein ID is recorded as NP_001365990^[19].
Lymphoid enhancer binding factor 1's RefSeq protein ID is recorded as NP_001365991^[20].
Lymphoid enhancer binding factor 1's RefSeq protein ID is recorded as XP_036018803^[21].
Lymphoid enhancer binding factor 1's RefSeq protein ID is recorded as XP_036018804^[22].
Lymphoid enhancer binding factor 1's PDB structure ID is recorded as 2LEF^[23].
Lymphoid enhancer binding factor 1's PDB structure ID is recorded as 3OUW^[24].
Lymphoid enhancer binding factor 1's PDB structure ID is recorded as 3OUX^[25].
Lymphoid enhancer binding factor 1's molecular function is recorded as DNA-binding transcription factor activity^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of Catenin binding domain superfamily, High mobility group box domain superfamily, lymphoid enhancer-binding factor 1, High mobility group box domain, protein family, CTNNB1 binding, N-teminal, protein family

Properties

Biological process somitogenesis, tongue development, paraxial mesoderm formation, negative regulation of DNA binding, T cell receptor V(D)J recombination, transcription by RNA polymerase II, cellular response to cytokine stimulus, mammary gland development, negative regulation of interleukin-13 production, odontogenesis of dentin-containing tooth, apoptotic process involved in blood vessel morphogenesis, cell chemotaxis, negative regulation of canonical Wnt signaling pathway, face morphogenesis, neutrophil differentiation, negative regulation of interleukin-5 production, regulation of transcription, DNA-templated, dentate gyrus development, apoptotic process involved in morphogenesis, transcription, DNA-templated, positive regulation of transcription, DNA-templated, regulation of Wnt signaling pathway, positive regulation of cell growth, embryonic limb morphogenesis, hypothalamus development, branching involved in blood vessel morphogenesis, trachea gland development, forebrain neuroblast division, eye pigmentation, negative regulation of apoptotic process, sprouting angiogenesis, negative regulation of transcription by RNA polymerase II, positive regulation of epithelial to mesenchymal transition, BMP signaling pathway, osteoblast differentiation, histone H3 acetylation, regulation of cell-cell adhesion, formation of radial glial scaffolds, epithelial to mesenchymal transition, positive regulation of granulocyte differentiation, alpha-beta T cell differentiation, canonical Wnt signaling pathway, negative regulation of transcription, DNA-templated, positive regulation by host of viral transcription, sensory perception of taste, cellular response to interleukin-4, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, cell development, negative regulation of interleukin-4 production, negative regulation of striated muscle tissue development, positive regulation of cell migration, Wnt signaling pathway, T-helper 1 cell differentiation, positive regulation of cell proliferation in bone marrow, anatomical structure regression, chorio-allantoic fusion, negative regulation of apoptotic process in bone marrow cell, B cell proliferation, positive regulation of gene expression, vasculature development, forebrain radial glial cell differentiation, neural crest cell migration, positive regulation of cell population proliferation, forebrain neuron differentiation, histone H4 acetylation, hippocampus development, positive regulation of transcription by RNA polymerase II, steroid hormone mediated signaling pathway, regulation of transcription by RNA polymerase II, negative regulation of cell-cell adhesion, positive regulation of cell-cell adhesion, positive regulation of cell cycle process, secondary palate development, odontoblast differentiation, Wnt signaling pathway, canonical Wnt signaling pathway, negative regulation of canonical Wnt signaling pathway, branching involved in blood vessel morphogenesis, somitogenesis, epithelial to mesenchymal transition, sprouting angiogenesis, regulation of transcription, DNA-templated, regulation of transcription by RNA polymerase II, dentate gyrus development, forebrain radial glial cell differentiation, forebrain neuroblast division, formation of radial glial scaffolds, regulation of cell-cell adhesion, embryonic limb morphogenesis, BMP signaling pathway, mammary gland development, B cell proliferation, alpha-beta T cell differentiation, paraxial mesoderm formation, face morphogenesis, apoptotic process involved in morphogenesis, chorio-allantoic fusion, trachea gland development, negative regulation of transcription, DNA-templated, positive regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II

Cell component cytoplasm, nucleus, transcription regulator complex, beta-catenin-TCF complex, protein-DNA complex, transcription regulator complex, cytoplasm, nucleus

Encoded by Lef1

Found in taxon house mouse

Has part(s) CTNNB1 binding, N-teminal, High mobility group box domain

Imported from wholeness_audit_2026-05-02

Molecular function DNA-binding transcription factor activity, DNA-binding transcription activator activity, RNA polymerase II-specific, histone deacetylase binding, armadillo repeat domain binding, estrogen receptor binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, transcription factor binding, estrogen receptor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, beta-catenin binding, gamma-catenin binding, histone binding, C2H2 zinc finger domain binding, chromatin binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protein binding, DNA binding, bending, DNA binding, sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding, chromatin binding, DNA-binding transcription factor activity, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding, sequence-specific DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific

External References (4)

Ensembl protein id ENSMUSP00000029611, ENSMUSP00000067808, ENSMUSP00000096211, ENSMUSP00000101948

Pdb structure id 2LEF, 3OUW, 3OUX

Refseq protein id NP_001263331, NP_001263332, NP_034833, XP_006501133, XP_030108300, NP_001365988, NP_001365989, NP_001365990, NP_001365991, XP_036018803, XP_036018804

Uniprot protein id P27782

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Lymphoid enhancer binding factor 1 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Lymphoid enhancer binding factor 1 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Lymphoid enhancer binding factor 1 — UniProt protein ID (P352): P27782. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Lymphoid enhancer binding factor 1 — part of (P361): Catenin binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Lymphoid enhancer binding factor 1 — part of (P361): High mobility group box domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Lymphoid enhancer binding factor 1 — part of (P361): lymphoid enhancer-binding factor 1. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Lymphoid enhancer binding factor 1 — part of (P361): High mobility group box domain, protein family. wikidata.org.
[9] ↑ Lymphoid enhancer binding factor 1 — part of (P361): CTNNB1 binding, N-teminal, protein family. wikidata.org.
[10] ↑ Lymphoid enhancer binding factor 1 — has part(s) (P527): CTNNB1 binding, N-teminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Lymphoid enhancer binding factor 1 — has part(s) (P527): High mobility group box domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Lymphoid enhancer binding factor 1 — RefSeq protein ID (P637): NP_001263331. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ Lymphoid enhancer binding factor 1 — RefSeq protein ID (P637): NP_001263332. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ Lymphoid enhancer binding factor 1 — RefSeq protein ID (P637): NP_034833. Q20641742. Retrieved 2022-03-20. wikidata.org.
[15] ↑ Lymphoid enhancer binding factor 1 — RefSeq protein ID (P637): XP_006501133. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ Lymphoid enhancer binding factor 1 — RefSeq protein ID (P637): XP_030108300. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ Lymphoid enhancer binding factor 1 — RefSeq protein ID (P637): NP_001365988. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ Lymphoid enhancer binding factor 1 — RefSeq protein ID (P637): NP_001365989. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ Lymphoid enhancer binding factor 1 — RefSeq protein ID (P637): NP_001365990. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ Lymphoid enhancer binding factor 1 — RefSeq protein ID (P637): NP_001365991. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ Lymphoid enhancer binding factor 1 — RefSeq protein ID (P637): XP_036018803. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Lymphoid enhancer binding factor 1 — RefSeq protein ID (P637): XP_036018804. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Lymphoid enhancer binding factor 1 — PDB structure ID (P638): 2LEF. Q905695. Retrieved 2016-08-10. wikidata.org.
[24] ↑ Lymphoid enhancer binding factor 1 — PDB structure ID (P638): 3OUW. Q905695. Retrieved 2016-08-10. wikidata.org.
[25] ↑ Lymphoid enhancer binding factor 1 — PDB structure ID (P638): 3OUX. Q905695. Retrieved 2016-08-10. wikidata.org.
[26] ↑ Lymphoid enhancer binding factor 1 — molecular function (P680): DNA-binding transcription factor activity. GOA. Retrieved 2018-07-16. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Lymphoid enhancer binding factor 1 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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BibTeX

@misc{4ortxyz_lymphoid-enhancer-binding-factor-1-q21498209_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Lymphoid enhancer binding factor 1}}, year = {2026}, url = {https://4ort.xyz/entity/lymphoid-enhancer-binding-factor-1-q21498209}, note = {Accessed: 2026-05-03}}

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