LPL
protein-coding gene in the species Homo sapiens
Facts
16 properties- Instance of
- gene
- Subclass of
- protein-coding gene
- Biological process
- retinoid metabolic process, lipid metabolism, fatty acid biosynthetic process, triglyceride metabolic process, phospholipid metabolic process, response to cold, response to glucose, positive regulation of macrophage derived foam cell differentiation, positive regulation of cholesterol storage, positive regulation of sequestering of triglyceride, lipid catabolic process, triglyceride biosynthetic process, triglyceride catabolic process, chylomicron remodeling, very-low-density lipoprotein particle remodeling, cholesterol homeostasis, positive regulation of inflammatory response, regulation of lipoprotein lipase activity, low-density lipoprotein particle mediated signaling, triglyceride homeostasis[28][29][30][31][32][33][34][35][36][37][38][39][40][41]
- Cell component
- extracellular region, extracellular space, plasma membrane, cell surface, membrane, extracellular matrix, anchored component of membrane, very-low-density lipoprotein particle, chylomicron, extracellular exosome[18][19][20][21][22][23][24][25][26][27]
- Chromosome
- human chromosome 8[46]
- Cytogenetic location
- 8p21.3
- Encodes
- lipoprotein lipase, Lipoprotein lipase[44]
- Expressed in
- olfactory bulb, trigeminal ganglion, right ventricle, spinal ganglia, myocardium of left ventricle, adipose tissue, abdominal fat, subcutaneous adipose tissue, apex of heart, tibial nerve
- Found in taxon
- Homo sapiens[45]
- Genetic association
- metabolic disease, lipid metabolism disorder, familial lipoprotein lipase deficiency, hyperlipoproteinemia, type 1D, mixed hyperlipidemia[47][48][49][50][51]
- HomoloGene ID
- 200[3]
- Molecular function
- lipoprotein lipase activity, phospholipase activity, triglyceride lipase activity, signaling receptor binding, protein binding, heparin binding, hydrolase activity, triglyceride binding, apolipoprotein binding, carboxylic ester hydrolase activity[8][9][10][11][12][13][14][15][16][17]
- Strand orientation
- forward strand[52]
🏷️ Also known as
en HDLCQ11
en LIPD
en lipoprotein lipase
en LPL
ar ليباز البروتين الشحمي
da Lipoproteinlipase
fi Lipoproteiinilipaasi
it Lipoproteina lipasi
ja リポタンパク質リパーゼ
ru Липопротеинлипаза
tr Lipoprotein lipaz
zh LPL (基因)
zh 脂蛋白脂肪酶
🔖 Identifiers · 10
- Encyclopædia Britannica Online ID
- topic/lipoprotein-lipase
- Ensembl gene ID
- ENSG00000175445
- Ensembl transcript ID
- ENST00000524029, ENST00000519773, ENST00000520959, ENST00000521994, ENST00000522701, ENST00000523696, ENST00000650478, ENST00000650287
- Entrez Gene ID
- 4023
- Exact match
- identifiers.org
- HGNC ID
- 6677
- HGNC gene symbol
- LPL
- OMIM ID
- 609708
- RefSeq RNA ID
- NM_000237
- UMLS CUI
- C1416902
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