Leptin

mammalian protein found in Rattus norvegicus
Protein protein Q28560385
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Leptin

Summary

Leptin is a protein[1].

Key Facts

  • Leptin's instance of is recorded as protein[2].
  • Leptin's subclass of is recorded as protein[3].
  • Leptin's UniProt protein ID is recorded as P50596[4].
  • Leptin's part of is recorded as leptin[5].
  • Leptin's part of is recorded as four-helical cytokine-like, core[6].
  • Leptin's RefSeq protein ID is recorded as NP_037208[7].
  • Leptin's RefSeq protein ID is recorded as XP_038963054[8].
  • Leptin's molecular function is recorded as signaling receptor binding[9].
  • Leptin's molecular function is recorded as cytokine activity[10].
  • Leptin's molecular function is recorded as hormone activity[11].
  • Leptin's molecular function is recorded as peptide hormone receptor binding[12].
  • Leptin's cell component is recorded as extracellular region[13].
  • Leptin's cell component is recorded as extracellular space[14].
  • Leptin's cell component is recorded as cytoplasm[15].
  • Leptin's biological process is recorded as negative regulation of transcription by RNA polymerase II[16].
  • Leptin's biological process is recorded as angiogenesis[17].
  • Leptin's biological process is recorded as ovulation from ovarian follicle[18].
  • Leptin's biological process is recorded as response to hypoxia[19].
  • Leptin's biological process is recorded as positive regulation of cytokine production[20].
  • Leptin's biological process is recorded as placenta development[21].
  • Leptin's biological process is recorded as regulation of protein phosphorylation[22].
  • Leptin's biological process is recorded as regulation of endothelial cell proliferation[23].
  • Leptin's biological process is recorded as response to dietary excess[24].
  • Leptin's biological process is recorded as cardiac muscle hypertrophy[25].
  • Leptin's biological process is recorded as glucose metabolic process[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . Q905695. Retrieved . wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . Q20641742. Retrieved . wikidata.org.
  7. [8] . Q20641742. Retrieved . wikidata.org.
  8. [9] . Evidence indicating that renal tubular metabolism of leptin is mediated by megalin but not by the leptin receptors. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . Specific increase in leptin production in obese (falfa) rat adipose cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . A short form of leptin receptor performs signal transduction. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . Inhibitory effect of leptin on the rat ovary during the ovulatory process. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . Rat heart is a site of leptin production and action. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . Leptin modulates cell morphology and cytokine release in microglia. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Central overexpression of leptin antagonist reduces wheel running and underscores importance of endogenous leptin receptor activity in energy homeostasis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . Leptin induces hypertrophy through activating the peroxisome proliferator‐activated receptor α pathway in cultured neonatal rat cardiomyocytes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Leptin. Retrieved May 3, 2026, from https://4ort.xyz/entity/leptin-q28560385
MLA “Leptin.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/leptin-q28560385.
BibTeX @misc{4ortxyz_leptin-q28560385_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Leptin}}, year = {2026}, url = {https://4ort.xyz/entity/leptin-q28560385}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Leptin — https://4ort.xyz/entity/leptin-q28560385 (retrieved 2026-05-03)

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