lecithin-cholesterol acyltransferase

mammalian protein found in Homo sapiens
Protein protein Q424716
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lecithin-cholesterol acyltransferase

Summary

lecithin-cholesterol acyltransferase is a protein[1]. It draws 239 Wikipedia views per month (protein category, ranking #139 of 987).[2]

Key Facts

  • lecithin-cholesterol acyltransferase's instance of is recorded as protein[3].
  • lecithin-cholesterol acyltransferase is part of Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase[4].
  • lecithin-cholesterol acyltransferase is part of Alpha/Beta hydrolase fold[5].
  • lecithin-cholesterol acyltransferase's molecular function is recorded as transferase activity[6].
  • lecithin-cholesterol acyltransferase's molecular function is recorded as O-acyltransferase activity[7].
  • lecithin-cholesterol acyltransferase's molecular function is recorded as apolipoprotein A-I binding[8].
  • lecithin-cholesterol acyltransferase's molecular function is recorded as protein binding[9].
  • lecithin-cholesterol acyltransferase's molecular function is recorded as acyltransferase activity[10].
  • lecithin-cholesterol acyltransferase's molecular function is recorded as phosphatidylcholine-sterol O-acyltransferase activity[11].
  • lecithin-cholesterol acyltransferase's cell component is recorded as extracellular region[12].
  • lecithin-cholesterol acyltransferase's cell component is recorded as high-density lipoprotein particle[13].
  • lecithin-cholesterol acyltransferase's cell component is recorded as extracellular exosome[14].
  • lecithin-cholesterol acyltransferase's cell component is recorded as extracellular space[15].
  • lecithin-cholesterol acyltransferase's cell component is recorded as extracellular exosome[16].
  • lecithin-cholesterol acyltransferase's biological process is recorded as steroid metabolic process[17].
  • lecithin-cholesterol acyltransferase's biological process is recorded as regulation of high-density lipoprotein particle assembly[18].
  • lecithin-cholesterol acyltransferase's biological process is recorded as lipid metabolism[19].
  • lecithin-cholesterol acyltransferase's biological process is recorded as cholesterol transport[20].
  • lecithin-cholesterol acyltransferase's biological process is recorded as cholesterol metabolic process[21].
  • lecithin-cholesterol acyltransferase's biological process is recorded as cholesterol esterification[22].
  • lecithin-cholesterol acyltransferase's biological process is recorded as very-low-density lipoprotein particle remodeling[23].
  • lecithin-cholesterol acyltransferase's biological process is recorded as phospholipid metabolic process[24].
  • lecithin-cholesterol acyltransferase's biological process is recorded as lipoprotein biosynthetic process[25].
  • lecithin-cholesterol acyltransferase's biological process is recorded as cholesterol homeostasis[26].
  • lecithin-cholesterol acyltransferase's biological process is recorded as phosphatidylcholine biosynthetic process[27].

Why It Matters

lecithin-cholesterol acyltransferase draws 239 Wikipedia views per month (protein category, ranking #139 of 987).[2] It has Wikipedia articles in 12 language editions, a strong signal of global cultural recognition.[28] It is known by 27 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  5. [7] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] . Interaction of rat lecithin-cholesterol acyltransferase with rat apolipoprotein A-I and with lecithin-cholesterol vesicles. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] . Interaction of lecithin:cholesterol acyltransferase (LCAT).alpha 2-macroglobulin complex with low density lipoprotein receptor-related protein (LRP). Evidence for an alpha 2-macroglobulin/LRP receptor-mediated system participating in LCAT clearance. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . Distribution and localization of lecithin:cholesterol acyltransferase and cholesteryl ester transfer activity in A-I-containing lipoproteins. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . Fractional efflux and net change in cellular cholesterol content mediated by sera from mice expressing both human apolipoprotein AI and human lecithin:cholesterol acyltransferase genes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . The high-resolution crystal structure of human LCAT. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . Apolipoprotein E is the major physiological activator of lecithin-cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . A protein cofactor of lecithin:cholesterol acyltransferase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . A protein cofactor of lecithin:cholesterol acyltransferase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . Role of the interfacial binding domain in the oxidative susceptibility of lecithin:cholesterol acyltransferase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). lecithin-cholesterol acyltransferase. Retrieved May 3, 2026, from https://4ort.xyz/entity/lecithin-cholesterol-acyltransferase
MLA “lecithin-cholesterol acyltransferase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/lecithin-cholesterol-acyltransferase.
BibTeX @misc{4ortxyz_lecithin-cholesterol-acyltransferase_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{lecithin-cholesterol acyltransferase}}, year = {2026}, url = {https://4ort.xyz/entity/lecithin-cholesterol-acyltransferase}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): lecithin-cholesterol acyltransferase — https://4ort.xyz/entity/lecithin-cholesterol-acyltransferase (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 9w ago · Boghog · 2026-07-23 view diff on Wikidata ↗
    Instance of
    Part of
    Encoded by LCAT
    Biological process steroid metabolic process, regulation of high-density lipoprotein particle assembly, lipid metabolism +11
    + 7 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.3.1.43, [[:toollabs:quickstatements/#/batch/261446|batch #261446]]"
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