Lambert-Eaton myasthenic syndrome
an autoimmune, presynaptic disorder of neuromuscular transmission characterized by fluctuating muscle weakness and autonomic dysfunction frequently associated with small-cell lung cancer (SCLC)
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Summary
Lambert-Eaton myasthenic syndrome is a class of disease[1]. It draws 2,039 Wikipedia views per month (class of disease category, ranking #499 of 1,968).[2]
Key Facts
- Named after: Edward H. Lambert[3], Lee M. Eaton[4]
- Subclass of: neuromuscular junction disease[5], channelopathy[6], immune-mediated acquired neuromuscular junction disease[7], paraneoplastic neurologic syndrome[8], autoimmune disease of musculoskeletal system[9], autoimmune disease of peripheral nervous system[10]
- Prevalence: 0.000005[11]
- ICD-9-CM: 358.3[12]
- NCI Thesaurus ID: C3155[13]
- Health specialty: neurology[14]
- Age of onset: adult onset[15]
- Exact match: http://purl.obolibrary.org/obo/DOID_0050214[16], http://identifiers.org/doid/DOID:0050214[17], http://www.orpha.net/ORDO/Orphanet_43393[18]
- On focus list of Wikimedia project: WikiProject Medicine[19]
- Has phenotype: xerostomia[20], reduced tendon reflexes[21], Primary autonomic failure[22], Q141816328[23], erectile dysfunction[24], constipation[25], Q141815183[26], lung small cell carcinoma[27], hypohidrosis[28], keratoconjunctivitis sicca[29], Q141815433[30]
- P14914: D43393[31]
Why It Matters
Lambert-Eaton myasthenic syndrome has Wikipedia articles in 18 language editions, a strong signal of global cultural recognition.[32] It is known by 58 alternative names across languages and contexts.[33]