Lacritin

mammalian protein found in Homo sapiens
Protein protein Q1759126
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Lacritin

Summary

Lacritin is a protein[1]. Lacritin draws 7 Wikipedia views per month (protein category, ranking #151 of 987).[2]

Key Facts

  • Lacritin's instance of is recorded as protein[3].
  • Lacritin's UniProt protein ID is recorded as Q9GZZ8[4].
  • Lacritin's part of is recorded as Extracellular glycoprotein lacritin[5].
  • Lacritin's RefSeq protein ID is recorded as NP_150593[6].
  • Lacritin's Freebase ID is recorded as /m/0fdst2[7].
  • Lacritin's molecular function is recorded as laminin-1 binding[8].
  • Lacritin's molecular function is recorded as fibronectin binding[9].
  • Lacritin's molecular function is recorded as growth factor activity[10].
  • Lacritin's molecular function is recorded as collagen binding[11].
  • Lacritin's molecular function is recorded as protein N-terminus binding[12].
  • Lacritin's molecular function is recorded as protein binding[13].
  • Lacritin's cell component is recorded as extracellular region[14].
  • Lacritin's cell component is recorded as secretory granule[15].
  • Lacritin's cell component is recorded as extracellular space[16].
  • Lacritin's cell component is recorded as extracellular region[17].
  • Lacritin's cell component is recorded as extracellular space[18].
  • Lacritin's cell component is recorded as secretory granule[19].
  • Lacritin's biological process is recorded as positive regulation of peptidyl-tyrosine phosphorylation[20].
  • Lacritin's biological process is recorded as calcineurin-NFAT signaling cascade[21].
  • Lacritin's biological process is recorded as positive regulation of release of sequestered calcium ion into cytosol[22].
  • Lacritin's biological process is recorded as calcium-mediated signaling[23].
  • Lacritin's biological process is recorded as positive regulation of epithelial cell proliferation[24].
  • Lacritin's biological process is recorded as protein localization to Golgi apparatus[25].
  • Lacritin's biological process is recorded as epithelial structure maintenance[26].
  • Lacritin's biological process is recorded as protein acetylation[27].

Why It Matters

Lacritin draws 7 Wikipedia views per month (protein category, ranking #151 of 987).[2]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . Q905695. Retrieved . wikidata.org.
  3. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] . Q20641742. Retrieved . wikidata.org.
  5. [7] . wikidata.org.
  6. [8] . cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] . cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] . Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] . cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] . Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . Restricted epithelial proliferation by lacritin via PKCalpha-dependent NFAT and mTOR pathways. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . Restricted epithelial proliferation by lacritin via PKCalpha-dependent NFAT and mTOR pathways. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . Restricted epithelial proliferation by lacritin via PKCalpha-dependent NFAT and mTOR pathways. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . Restricted epithelial proliferation by lacritin via PKCalpha-dependent NFAT and mTOR pathways. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . Restricted epithelial proliferation by lacritin via PKCalpha-dependent NFAT and mTOR pathways. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . Topical administration of lacritin is a novel therapy for aqueous-deficient dry eye disease. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . Lacritin rescues stressed epithelia via rapid forkhead box O3 (FOXO3)-associated autophagy that restores metabolism. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Lacritin. Retrieved May 3, 2026, from https://4ort.xyz/entity/lacritin
MLA “Lacritin.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/lacritin.
BibTeX @misc{4ortxyz_lacritin_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Lacritin}}, year = {2026}, url = {https://4ort.xyz/entity/lacritin}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Lacritin — https://4ort.xyz/entity/lacritin (retrieved 2026-05-03)

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