KRIT1 ankyrin repeat containing

mammalian protein found in Homo sapiens

Protein protein Q21117068

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Summary

KRIT1 ankyrin repeat containing is a protein^[1].

Key Facts

KRIT1 ankyrin repeat containing's instance of is recorded as protein^[2].
KRIT1 ankyrin repeat containing's UniProt protein ID is recorded as O00522^[3].
KRIT1 ankyrin repeat containing's UniProt protein ID is recorded as C9JD81^[4].
KRIT1 ankyrin repeat containing's part of is recorded as FERM/acyl-CoA-binding protein superfamily^[5].
KRIT1 ankyrin repeat containing's part of is recorded as PH-like domain superfamily^[6].
KRIT1 ankyrin repeat containing's part of is recorded as FERM superfamily, second domain^[7].
KRIT1 ankyrin repeat containing's part of is recorded as Ankyrin repeat-containing domain superfamily^[8].
KRIT1 ankyrin repeat containing's part of is recorded as Band 4.1 domain, protein family^[9].
KRIT1 ankyrin repeat containing's part of is recorded as FERM central domain, protein family^[10].
KRIT1 ankyrin repeat containing's part of is recorded as Ankyrin repeat-containing domain, protein family^[11].
KRIT1 ankyrin repeat containing's part of is recorded as KRIT, N-terminal NPxY motif-rich region, protein family^[12].
KRIT1 ankyrin repeat containing's part of is recorded as FERM domain, protein family^[13].
KRIT1 ankyrin repeat containing's part of is recorded as Ankyrin repeat, protein family^[14].
KRIT1 ankyrin repeat containing's MeSH descriptor ID is recorded as D000075927^[15].
KRIT1 ankyrin repeat containing's has part is recorded as KRIT, N-terminal NPxY motif-rich region^[16].
KRIT1 ankyrin repeat containing's has part is recorded as ankyrin repeat-containing domain^[17].
KRIT1 ankyrin repeat containing's has part is recorded as Band 4.1 domain^[18].
KRIT1 ankyrin repeat containing's has part is recorded as ankyrin repeat^[19].
KRIT1 ankyrin repeat containing's has part is recorded as FERM central domain^[20].
KRIT1 ankyrin repeat containing's has part is recorded as FERM domain^[21].
KRIT1 ankyrin repeat containing's RefSeq protein ID is recorded as NP_001013424^[22].
KRIT1 ankyrin repeat containing's RefSeq protein ID is recorded as NP_004903^[23].
KRIT1 ankyrin repeat containing's RefSeq protein ID is recorded as NP_919436^[24].
KRIT1 ankyrin repeat containing's RefSeq protein ID is recorded as NP_919437^[25].
KRIT1 ankyrin repeat containing's RefSeq protein ID is recorded as NP_919438^[26].

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Quick Facts

Instance of protein

Part of FERM/acyl-CoA-binding protein superfamily, PH-like domain superfamily, FERM superfamily, second domain, Ankyrin repeat-containing domain superfamily, Band 4.1 domain, protein family, FERM central domain, protein family, Ankyrin repeat-containing domain, protein family, KRIT, N-terminal NPxY motif-rich region, protein family, FERM domain, protein family, Ankyrin repeat, protein family

Properties

Biological process regulation of establishment of cell polarity, negative regulation of angiogenesis, small GTPase mediated signal transduction, angiogenesis, negative regulation of endothelial cell proliferation, negative regulation of endothelial cell apoptotic process, negative regulation of endothelial cell migration, positive regulation of protein binding, cell redox homeostasis, regulation of catalytic activity, negative regulation of angiogenesis, cell redox homeostasis, regulation of establishment of cell polarity

Cell component cytoskeleton, membrane, microtubule, plasma membrane, cytoplasm, cell-cell junction, cell junction, extracellular space, extracellular space

Encoded by KRIT1

Found in taxon Homo sapiens

Has part(s) KRIT, N-terminal NPxY motif-rich region, ankyrin repeat-containing domain, Band 4.1 domain, ankyrin repeat, FERM central domain, FERM domain

Imported from wholeness_audit_2026-05-02

Molecular function microtubule binding, protein binding, phosphatidylinositol-4,5-bisphosphate binding, protein-containing complex binding, GTPase regulator activity

External References (7)

Ensembl protein id ENSP00000395604, ENSP00000395346, ENSP00000405835, ENSP00000396352, ENSP00000378015, ENSP00000404084, ENSP00000344668, ENSP00000378013, ENSP00000391540, ENSP00000388076, ENSP00000391675, ENSP00000378011, ENSP00000396042, ENSP00000404790, ENSP00000410104, ENSP00000414694, ENSP00000410467, ENSP00000410909

Mesh descriptor id D000075927

Mesh tree code D12.776.220.600.450.458, D12.776.624.664.700.119, D12.776.631.560.465

Pdb structure id 3U7D, 4DX8, 4DXA, 4HDO, 4HDQ, 4JIF, 4TKN, 5D68

Refseq protein id NP_001013424, NP_004903, NP_919436, NP_919437, NP_919438, NP_001337598, NP_001337599, NP_001337600, NP_001337601, NP_001337602, NP_001337603, NP_001337604, NP_001337605, NP_001337606, NP_001337607, NP_001337608, NP_001337609, NP_001337610, NP_001337611, NP_001337612, NP_001337613, NP_001337614, NP_001337615, NP_001337616, NP_001337617, NP_001337618, NP_001337619, NP_001337620, NP_001337621, NP_001337622, NP_001337623, NP_001337624, NP_001337625, NP_001337626

Umls cui C4318443

Uniprot protein id O00522, C9JD81

🏷️ Also known as

en ankyrin repeat-containing protein Krit1 en cerebral cavernous malformations 1 protein en krev interaction trapped 1 en krev interaction trapped protein 1 en KRIT1 en KRIT1 ankyrin repeat containing en KRIT1 Protein nl KRIT1, ankyrin repeat containing

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ KRIT1 ankyrin repeat containing — instance of (P31): protein. UniProt. Retrieved 2019-11-13. wikidata.org.
[3] ↑ KRIT1 ankyrin repeat containing — UniProt protein ID (P352): O00522. UniProt. Retrieved 2019-11-13. wikidata.org.
[4] ↑ KRIT1 ankyrin repeat containing — UniProt protein ID (P352): C9JD81. UniProt. Retrieved 2016-03-20. wikidata.org.
[5] ↑ KRIT1 ankyrin repeat containing — part of (P361): FERM/acyl-CoA-binding protein superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ KRIT1 ankyrin repeat containing — part of (P361): PH-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ KRIT1 ankyrin repeat containing — part of (P361): FERM superfamily, second domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ KRIT1 ankyrin repeat containing — part of (P361): Ankyrin repeat-containing domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ KRIT1 ankyrin repeat containing — part of (P361): Band 4.1 domain, protein family. wikidata.org.
[10] ↑ KRIT1 ankyrin repeat containing — part of (P361): FERM central domain, protein family. wikidata.org.
[11] ↑ KRIT1 ankyrin repeat containing — part of (P361): Ankyrin repeat-containing domain, protein family. wikidata.org.
[12] ↑ KRIT1 ankyrin repeat containing — part of (P361): KRIT, N-terminal NPxY motif-rich region, protein family. wikidata.org.
[13] ↑ KRIT1 ankyrin repeat containing — part of (P361): FERM domain, protein family. wikidata.org.
[14] ↑ KRIT1 ankyrin repeat containing — part of (P361): Ankyrin repeat, protein family. wikidata.org.
[15] ↑ KRIT1 ankyrin repeat containing — MeSH descriptor ID (P486): D000075927. wikidata.org.
[16] ↑ KRIT1 ankyrin repeat containing — has part(s) (P527): KRIT, N-terminal NPxY motif-rich region. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ KRIT1 ankyrin repeat containing — has part(s) (P527): ankyrin repeat-containing domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ KRIT1 ankyrin repeat containing — has part(s) (P527): Band 4.1 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ KRIT1 ankyrin repeat containing — has part(s) (P527): ankyrin repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ KRIT1 ankyrin repeat containing — has part(s) (P527): FERM central domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ KRIT1 ankyrin repeat containing — has part(s) (P527): FERM domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ KRIT1 ankyrin repeat containing — RefSeq protein ID (P637): NP_001013424. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ KRIT1 ankyrin repeat containing — RefSeq protein ID (P637): NP_004903. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ KRIT1 ankyrin repeat containing — RefSeq protein ID (P637): NP_919436. Q20641742. Retrieved 2020-05-30. wikidata.org.
[25] ↑ KRIT1 ankyrin repeat containing — RefSeq protein ID (P637): NP_919437. Q20641742. Retrieved 2020-05-30. wikidata.org.
[26] ↑ KRIT1 ankyrin repeat containing — RefSeq protein ID (P637): NP_919438. Q20641742. Retrieved 2020-05-30. wikidata.org.

Class ancestry

[1] ↑ KRIT1 ankyrin repeat containing is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). KRIT1 ankyrin repeat containing. Retrieved May 3, 2026, from https://4ort.xyz/entity/krit1-ankyrin-repeat-containing-q21117068

MLA

“KRIT1 ankyrin repeat containing.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/krit1-ankyrin-repeat-containing-q21117068.

BibTeX

@misc{4ortxyz_krit1-ankyrin-repeat-containing-q21117068_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{KRIT1 ankyrin repeat containing}}, year = {2026}, url = {https://4ort.xyz/entity/krit1-ankyrin-repeat-containing-q21117068}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): KRIT1 ankyrin repeat containing — https://4ort.xyz/entity/krit1-ankyrin-repeat-containing-q21117068 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/krit1-ankyrin-repeat-containing-q21117068 · Last refreshed: May 3, 2026