Janus kinase 3

mammalian protein found in Mus musculus

Protein protein Q14914500

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Janus kinase 3

Summary

Janus kinase 3 is a protein^[1].

Key Facts

Janus kinase 3's instance of is recorded as protein^[2].
Janus kinase 3's UniProt protein ID is recorded as Franz Xaver Gabelsberger^[3].
Janus kinase 3's part of is recorded as Protein kinase-like domain superfamily^[4].
Janus kinase 3's part of is recorded as tyrosine-protein kinase, non-receptor Jak3^[5].
Janus kinase 3's part of is recorded as SH2 domain superfamily^[6].
Janus kinase 3's part of is recorded as membrane protein^[7].
Janus kinase 3's part of is recorded as Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family^[8].
Janus kinase 3's part of is recorded as SH2 domain, protein family^[9].
Janus kinase 3's part of is recorded as Band 4.1 domain, protein family^[10].
Janus kinase 3's part of is recorded as FERM domain, protein family^[11].
Janus kinase 3's part of is recorded as Protein kinase domain, protein family^[12].
Janus kinase 3's part of is recorded as Protein kinase, ATP binding site, protein family^[13].
Janus kinase 3's part of is recorded as Tyrosine-protein kinase, catalytic domain, protein family^[14].
Janus kinase 3's part of is recorded as Tyrosine-protein kinase, active site, protein family^[15].
Janus kinase 3's has part is recorded as SH2 domain^[16].
Janus kinase 3's has part is recorded as tyrosine-protein kinase, catalytic domain^[17].
Janus kinase 3's has part is recorded as tyrosine-protein kinase, active site^[18].
Janus kinase 3's has part is recorded as FERM domain^[19].
Janus kinase 3's has part is recorded as serine-threonine/tyrosine-protein kinase, catalytic domain^[20].
Janus kinase 3's has part is recorded as protein kinase, ATP binding site^[21].
Janus kinase 3's has part is recorded as Band 4.1 domain^[22].
Janus kinase 3's has part is recorded as protein kinase domain^[23].
Janus kinase 3's RefSeq protein ID is recorded as NP_001177759^[24].
Janus kinase 3's RefSeq protein ID is recorded as NP_034719^[25].
Janus kinase 3's molecular function is recorded as transferase activity^[26].

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Quick Facts

Instance of protein

Part of Protein kinase-like domain superfamily, tyrosine-protein kinase, non-receptor Jak3, SH2 domain superfamily, membrane protein, Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family, SH2 domain, protein family, Band 4.1 domain, protein family, FERM domain, protein family, Protein kinase domain, protein family, Protein kinase, ATP binding site, protein family, Tyrosine-protein kinase, catalytic domain, protein family, Tyrosine-protein kinase, active site, protein family

Properties

Biological process negative regulation of FasL production, negative regulation of interleukin-10 production, response to interleukin-15, intracellular signal transduction, adaptive immune response, response to interleukin-4, phosphorylation, interleukin-4-mediated signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, immune system process, response to interleukin-2, negative regulation of thymocyte apoptotic process, cellular response to cytokine stimulus, T cell homeostasis, protein phosphorylation, positive regulation of extrinsic apoptotic signaling pathway in absence of ligand, negative regulation of T-helper 1 cell differentiation, negative regulation of dendritic cell cytokine production, regulation of T cell apoptotic process, positive regulation of dendritic cell apoptotic process, peptidyl-tyrosine autophosphorylation, peptidyl-tyrosine phosphorylation, B cell differentiation, innate immune response, lymph node development, negative regulation of T cell activation, enzyme linked receptor protein signaling pathway, cell migration, response to interleukin-9, positive regulation of transcription by RNA polymerase II, negative regulation of interleukin-12 production, inflammatory response, erythrocyte differentiation, tyrosine phosphorylation of STAT protein, positive regulation of cytosolic calcium ion concentration, cytokine-mediated signaling pathway, positive regulation of T cell proliferation, positive regulation of activated T cell proliferation, positive regulation of nitric-oxide synthase biosynthetic process, positive regulation of calcium ion transport, cytokine-mediated signaling pathway, B cell differentiation, T cell homeostasis, innate immune response

Cell component membrane, extrinsic component of cytoplasmic side of plasma membrane, intracellular anatomical structure, cytoskeleton, endomembrane system, cytosol, cytoplasm

Encoded by Jak3

Found in taxon house mouse

Has part(s) SH2 domain, tyrosine-protein kinase, catalytic domain, tyrosine-protein kinase, active site, FERM domain, serine-threonine/tyrosine-protein kinase, catalytic domain, protein kinase, ATP binding site, Band 4.1 domain, protein kinase domain

Imported from wholeness_audit_2026-05-02

Molecular function transferase activity, nucleotide binding, protein kinase activity, non-membrane spanning protein tyrosine kinase activity, kinase activity, protein binding, protein phosphatase binding, signaling receptor binding, ATP binding, protein tyrosine kinase activity, non-membrane spanning protein tyrosine kinase activity

External References (3)

Ensembl protein id ENSMUSP00000060073, ENSMUSP00000105639, ENSMUSP00000105640

Refseq protein id NP_001177759, NP_034719

Uniprot protein id Franz Xaver Gabelsberger

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Janus kinase 3 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Janus kinase 3 — UniProt protein ID (P352): Franz Xaver Gabelsberger. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ Janus kinase 3 — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Janus kinase 3 — part of (P361): tyrosine-protein kinase, non-receptor Jak3. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Janus kinase 3 — part of (P361): SH2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Janus kinase 3 — part of (P361): membrane protein. wikidata.org.
[8] ↑ Janus kinase 3 — part of (P361): Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[9] ↑ Janus kinase 3 — part of (P361): SH2 domain, protein family. wikidata.org.
[10] ↑ Janus kinase 3 — part of (P361): Band 4.1 domain, protein family. wikidata.org.
[11] ↑ Janus kinase 3 — part of (P361): FERM domain, protein family. wikidata.org.
[12] ↑ Janus kinase 3 — part of (P361): Protein kinase domain, protein family. wikidata.org.
[13] ↑ Janus kinase 3 — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[14] ↑ Janus kinase 3 — part of (P361): Tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[15] ↑ Janus kinase 3 — part of (P361): Tyrosine-protein kinase, active site, protein family. wikidata.org.
[16] ↑ Janus kinase 3 — has part(s) (P527): SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Janus kinase 3 — has part(s) (P527): tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Janus kinase 3 — has part(s) (P527): tyrosine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Janus kinase 3 — has part(s) (P527): FERM domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Janus kinase 3 — has part(s) (P527): serine-threonine/tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Janus kinase 3 — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Janus kinase 3 — has part(s) (P527): Band 4.1 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Janus kinase 3 — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Janus kinase 3 — RefSeq protein ID (P637): NP_001177759. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Janus kinase 3 — RefSeq protein ID (P637): NP_034719. Q20641742. Retrieved 2022-03-20. wikidata.org.
[26] ↑ Janus kinase 3 — molecular function (P680): transferase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Janus kinase 3 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Janus kinase 3. Retrieved May 3, 2026, from https://4ort.xyz/entity/janus-kinase-3-q14914500

MLA “Janus kinase 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/janus-kinase-3-q14914500.

BibTeX

@misc{4ortxyz_janus-kinase-3-q14914500_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Janus kinase 3}}, year = {2026}, url = {https://4ort.xyz/entity/janus-kinase-3-q14914500}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Janus kinase 3 — https://4ort.xyz/entity/janus-kinase-3-q14914500 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/janus-kinase-3-q14914500 · Last refreshed: May 3, 2026