islet amyloid polypeptide
mammalian protein found in Homo sapiens
Facts
9 properties- Instance of
- protein
- Part of
- Pro-islet amyloid polypeptide, Calcitonin, conserved site, protein family, Calcitonin peptide-like family[2][3][4]
- Biological process
- negative regulation of cell differentiation, cell-cell signaling, sensory perception of pain, eating behavior, signal transduction, negative regulation of bone resorption, apoptotic process, negative regulation of cell population proliferation, protein destabilization, protein homooligomerization, amyloid fibril formation, G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, positive regulation of cytosolic calcium ion concentration, regulation of signaling receptor activity, positive regulation of protein kinase A signaling, negative regulation of mitochondrion organization, negative regulation of protein homooligomerization, positive regulation of apoptotic process, positive regulation of MAPK cascade, protein homooligomerization, positive regulation of protein kinase B signaling, amylin receptor signaling pathway, negative regulation of amyloid fibril formation
- Cell component
- extracellular region, soma, extracellular space, inclusion body, extracellular space
- Encoded by
- IAPP
- Found in taxon
- Homo sapiens
- Has parts
- Calcitonin, conserved site, Calcitonin peptide-like
- Molecular function
- signaling receptor binding, hormone activity, identical protein binding, amyloid-beta binding, protein binding, identical protein binding
🏷️ Also known as
en Islet amyloid polypeptide (diabetes-associated peptide; amylin)
en IAPP
en insulinoma amyloid peptide
en islet amyloid polypeptide
en amylin
en DAP
en diabetes-associated peptide
ar عديد الببتيد النشواني الجزيري
ar أميلين
cs IAPP
es Amilina
fa آمیلین (هورمون)
fr Amyline
fr IAPP
he אמלין
id Amilin
ja アミリン
pl Amylina
uk Амілін
zh 胰淀素
🔖 Identifiers · 11
- OpenAlex ID
- C2780705028
- Ensembl protein ID
- ENSP00000240652, ENSP00000437357, ENSP00000437559, ENSP00000445711, ENSP00000445980
- Exact match
- purl.uniprot.org
- Freebase ID
- /m/05gtc8
- MeSH descriptor ID
- D058228
- MeSH tree code
- D06.472.699.587.334, D12.644.548.586.234, D12.776.049.407.500
- Microsoft Academic ID (discontinued)
- 2780705028
- RefSeq protein ID
- NP_000406, NP_001316130
- UniProt protein ID
- P10997
- WikiSkripta article ID
- 71656
🔗 Connections
Biological process 3
Cell component 3
Found in taxon 1
Instance of 1
Molecular function 1
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Summary
islet amyloid polypeptide is a protein[1].