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Iodothyronine deiodinase 2

mammalian protein found in Homo sapiens
Protein protein Q21120665
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Iodothyronine deiodinase 2

Summary

Iodothyronine deiodinase 2 is a protein[1]. It is known by 13 alternative names across languages and contexts.[2]

Key Facts

  • Iodothyronine deiodinase 2's instance of is recorded as protein[3].
  • Iodothyronine deiodinase 2 is part of Thioredoxin-like superfamily[4].
  • Iodothyronine deiodinase 2 is part of Iodothyronine deiodinase[5].
  • Iodothyronine deiodinase 2 is part of Iodothyronine deiodinase, active site, protein family[6].
  • Iodothyronine deiodinase 2 comprises Iodothyronine deiodinase, active site[7].
  • Iodothyronine deiodinase 2's molecular function is recorded as oxidoreductase activity[8].
  • Iodothyronine deiodinase 2's molecular function is recorded as selenium binding[9].
  • Iodothyronine deiodinase 2's molecular function is recorded as thyroxine 5'-deiodinase activity[10].
  • Iodothyronine deiodinase 2's molecular function is recorded as ubiquitin protein ligase binding[11].
  • Iodothyronine deiodinase 2's molecular function is recorded as thyroxine 5'-deiodinase activity[12].
  • Iodothyronine deiodinase 2's cell component is recorded as integral component of membrane[13].
  • Iodothyronine deiodinase 2's cell component is recorded as plasma membrane[14].
  • Iodothyronine deiodinase 2's cell component is recorded as membrane[15].
  • Iodothyronine deiodinase 2's biological process is recorded as thyroid hormone metabolic process[16].
  • Iodothyronine deiodinase 2's biological process is recorded as thyroid hormone generation[17].
  • Iodothyronine deiodinase 2's biological process is recorded as selenocysteine incorporation[18].
  • Iodothyronine deiodinase 2's biological process is recorded as hormone biosynthetic process[19].
  • Iodothyronine deiodinase 2's biological process is recorded as thyroid hormone metabolic process[20].
  • Iodothyronine deiodinase 2's biological process is recorded as positive regulation of cold-induced thermogenesis[21].
  • Iodothyronine deiodinase 2's encoded by is recorded as DIO2[22].
  • Iodothyronine deiodinase 2's found in taxon is recorded as Homo sapiens[23].

Why It Matters

Iodothyronine deiodinase 2 is known by 13 alternative names across languages and contexts.[2]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . Q905695. Retrieved . wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . The 3'-untranslated region of human type 2 iodothyronine deiodinase mRNA contains a functional selenocysteine insertion sequence element. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . The 3'-untranslated region of human type 2 iodothyronine deiodinase mRNA contains a functional selenocysteine insertion sequence element. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . The 3'-untranslated region of human type 2 iodothyronine deiodinase mRNA contains a functional selenocysteine insertion sequence element. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . The 3'-untranslated region of human type 2 iodothyronine deiodinase mRNA contains a functional selenocysteine insertion sequence element. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . Q905695. Retrieved . wikidata.org.
  21. [23] ↑ . Q905695. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Iodothyronine deiodinase 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/iodothyronine-deiodinase-2
MLA “Iodothyronine deiodinase 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/iodothyronine-deiodinase-2.
BibTeX @misc{4ortxyz_iodothyronine-deiodinase-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Iodothyronine deiodinase 2}}, year = {2026}, url = {https://4ort.xyz/entity/iodothyronine-deiodinase-2}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 11w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → DIO2
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → oxidoreductase activity, selenium binding, thyroxine 5'-deiodinase activity +2
    + 12 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 1.21.99.4, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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