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Iodothyronine deiodinase 1

mammalian protein found in Homo sapiens
Protein protein Q21131597
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Summary

Iodothyronine deiodinase 1 is a protein[1]. It is known by 11 alternative names across languages and contexts.[2]

Key Facts

  • Part of: Thioredoxin-like superfamily[3], Iodothyronine deiodinase I/III[4], Iodothyronine deiodinase, active site, protein family[5]
  • Has part(s): Iodothyronine deiodinase, active site[6]
  • Molecular function: selenium binding[7], oxidoreductase activity[8], thyroxine 5'-deiodinase activity[9]
  • Cell component: endoplasmic reticulum membrane[10], plasma membrane[11], membrane[12], integral component of membrane[13], endoplasmic reticulum[14]
  • Biological process: thyroid hormone generation[15], hormone biosynthetic process[16], thyroid hormone metabolic process[17]
  • Encoded by: DIO1[18]
  • Found in taxon: Homo sapiens[19]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . UniProt. Retrieved . wikidata.org.
  17. [19] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Iodothyronine deiodinase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/iodothyronine-deiodinase-1
MLA “Iodothyronine deiodinase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/iodothyronine-deiodinase-1.
BibTeX @misc{4ortxyz_iodothyronine-deiodinase-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Iodothyronine deiodinase 1}}, year = {2026}, url = {https://4ort.xyz/entity/iodothyronine-deiodinase-1}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Iodothyronine deiodinase 1 — https://4ort.xyz/entity/iodothyronine-deiodinase-1 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 11w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → DIO1
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → selenium binding, oxidoreductase activity, thyroxine 5'-deiodinase activity +1
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 1.21.99.3, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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