Interleukin 3

mammalian protein found in Mus musculus
Protein protein Q21495866
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Interleukin 3

Summary

Interleukin 3 is a protein[1].

Key Facts

  • Interleukin 3's instance of is recorded as protein[2].
  • Interleukin 3's subclass of is recorded as protein[3].
  • Interleukin 3's UniProt protein ID is recorded as P01586[4].
  • Interleukin 3's part of is recorded as interleukin-3[5].
  • Interleukin 3's part of is recorded as four-helical cytokine-like, core[6].
  • Interleukin 3's RefSeq protein ID is recorded as NP_034686[7].
  • Interleukin 3's PDB structure ID is recorded as 2L3O[8].
  • Interleukin 3's molecular function is recorded as growth factor activity[9].
  • Interleukin 3's molecular function is recorded as interleukin-1 receptor binding[10].
  • Interleukin 3's molecular function is recorded as cytokine activity[11].
  • Interleukin 3's molecular function is recorded as interleukin-3 receptor binding[12].
  • Interleukin 3's cell component is recorded as extracellular region[13].
  • Interleukin 3's cell component is recorded as extracellular space[14].
  • Interleukin 3's biological process is recorded as positive regulation of protein phosphorylation[15].
  • Interleukin 3's biological process is recorded as response to hypoxia[16].
  • Interleukin 3's biological process is recorded as interleukin-3-mediated signaling pathway[17].
  • Interleukin 3's biological process is recorded as cytokine-mediated signaling pathway[18].
  • Interleukin 3's biological process is recorded as negative regulation of mast cell apoptotic process[19].
  • Interleukin 3's biological process is recorded as regulation of protein dephosphorylation[20].
  • Interleukin 3's biological process is recorded as negative regulation of apoptotic process[21].
  • Interleukin 3's biological process is recorded as positive regulation of JNK cascade[22].
  • Interleukin 3's biological process is recorded as monocyte differentiation[23].
  • Interleukin 3's biological process is recorded as regulation of glycolytic process[24].
  • Interleukin 3's biological process is recorded as positive regulation of myeloid leukocyte differentiation[25].
  • Interleukin 3's biological process is recorded as positive regulation of mast cell proliferation[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . Q905695. Retrieved . wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . Q20641742. Retrieved . wikidata.org.
  7. [8] . Q905695. Retrieved . wikidata.org.
  8. [9] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . A new isoform of interleukin-3 receptor {alpha} with novel differentiation activity and high affinity binding mode. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . Stat5 expression is critical for mast cell development and survival. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . A new isoform of interleukin-3 receptor {alpha} with novel differentiation activity and high affinity binding mode. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Stat5a is essential for the proliferation and survival of murine mast cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Interleukin 3. Retrieved May 3, 2026, from https://4ort.xyz/entity/interleukin-3-q21495866
MLA “Interleukin 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/interleukin-3-q21495866.
BibTeX @misc{4ortxyz_interleukin-3-q21495866_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Interleukin 3}}, year = {2026}, url = {https://4ort.xyz/entity/interleukin-3-q21495866}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Interleukin 3 — https://4ort.xyz/entity/interleukin-3-q21495866 (retrieved 2026-05-03)

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