interferon alpha 2

mammalian protein found in Homo sapiens
Protein protein Q22677926
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interferon alpha 2

Summary

interferon alpha 2 is a protein[1].

Key Facts

  • interferon alpha 2's instance of is recorded as protein[2].
  • interferon alpha 2's instance of is recorded as protein fragment[3].
  • interferon alpha 2 is part of interferon alpha/beta/delta[4].
  • interferon alpha 2 is part of four-helical cytokine-like, core[5].
  • interferon alpha 2 is part of prepro-interferon alpha-2[6].
  • interferon alpha 2's said to be the same as is recorded as interferon Alfa-2a, recombinant[7].
  • interferon alpha 2's molecular function is recorded as cytokine activity[8].
  • interferon alpha 2's molecular function is recorded as type I interferon receptor binding[9].
  • interferon alpha 2's molecular function is recorded as protein binding[10].
  • interferon alpha 2's molecular function is recorded as cytokine receptor binding[11].
  • interferon alpha 2's molecular function is recorded as type I interferon receptor binding[12].
  • interferon alpha 2's cell component is recorded as extracellular region[13].
  • interferon alpha 2's cell component is recorded as extracellular space[14].
  • interferon alpha 2's cell component is recorded as collagen-containing extracellular matrix[15].
  • interferon alpha 2's biological process is recorded as apoptotic process[16].
  • interferon alpha 2's biological process is recorded as defense response[17].
  • interferon alpha 2's biological process is recorded as negative regulation of viral entry into host cell[18].
  • interferon alpha 2's biological process is recorded as response to exogenous dsRNA[19].
  • interferon alpha 2's biological process is recorded as cell-cell signaling[20].
  • interferon alpha 2's biological process is recorded as negative regulation of T-helper 2 cell cytokine production[21].
  • interferon alpha 2's biological process is recorded as blood coagulation[22].
  • interferon alpha 2's biological process is recorded as positive regulation of peptidyl-serine phosphorylation of STAT protein[23].
  • interferon alpha 2's biological process is recorded as negative regulation of gene expression[24].
  • interferon alpha 2's biological process is recorded as positive regulation of transcription, DNA-templated[25].
  • interferon alpha 2's biological process is recorded as natural killer cell activation involved in immune response[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . wikidata.org.
  6. [7] . wikidata.org.
  7. [8] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] . At least three human type alpha interferons: structure of alpha 2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . Soluble and membrane-anchored forms of the human IFN-alpha/beta receptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . At least three human type alpha interferons: structure of alpha 2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Recombinant IFN-alpha (2b) increases the expression of apoptosis receptor CD95 and chemokine receptors CCR1 and CCR3 in monocytoid cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . The Sin3a repressor complex is a master regulator of STAT transcriptional activity. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . Recombinant IFN-alpha (2b) increases the expression of apoptosis receptor CD95 and chemokine receptors CCR1 and CCR3 in monocytoid cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . HCV NS5A inhibits interferon-alpha signaling through suppression of STAT1 phosphorylation in hepatocyte-derived cell lines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). interferon alpha 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/interferon-alpha-2
MLA “interferon alpha 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/interferon-alpha-2.
BibTeX @misc{4ortxyz_interferon-alpha-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{interferon alpha 2}}, year = {2026}, url = {https://4ort.xyz/entity/interferon-alpha-2}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 5w ago · MatSuBot bot · 2026-06-13 view diff on Wikidata ↗
    Part of interferon alpha/beta/delta, four-helical cytokine-like, core, prepro-interferon alpha-2
    Exact match https://www.uniprot.org/uniprot/P01563#PRO_0000016360
    Pdb structure id 1RH2, 3S9D, 1ITF +7
    Wikidata description mammalian protein found in Homo sapiens
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaimvalue:1| */ [[Property:P361]]: [[Q6046488]], fix redirect [[Q24780046]] → [[Q6046488]] ([[:toollabs:editgroups/b/CB/e90e8a1319ef|details]])"
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