Insulin receptor substrate 2

mammalian protein found in Mus musculus
Protein protein Q21986028
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Summary

Insulin receptor substrate 2 is a protein[1].

Key Facts

  • Insulin receptor substrate 2's instance of is recorded as protein[2].
  • Insulin receptor substrate 2's subclass of is recorded as protein[3].
  • Insulin receptor substrate 2's UniProt protein ID is recorded as P81122[4].
  • Insulin receptor substrate 2's RefSeq protein ID is recorded as NP_001074681[5].
  • Insulin receptor substrate 2's PDB structure ID is recorded as 3BU3[6].
  • Insulin receptor substrate 2's PDB structure ID is recorded as 3BU5[7].
  • Insulin receptor substrate 2's PDB structure ID is recorded as 3BU6[8].
  • Insulin receptor substrate 2's molecular function is recorded as protein kinase binding[9].
  • Insulin receptor substrate 2's molecular function is recorded as protein binding[10].
  • Insulin receptor substrate 2's molecular function is recorded as signal transducer activity[11].
  • Insulin receptor substrate 2's molecular function is recorded as insulin receptor binding[12].
  • Insulin receptor substrate 2's molecular function is recorded as protein phosphatase binding[13].
  • Insulin receptor substrate 2's molecular function is recorded as protein domain specific binding[14].
  • Insulin receptor substrate 2's molecular function is recorded as phosphatidylinositol 3-kinase binding[15].
  • Insulin receptor substrate 2's molecular function is recorded as 14-3-3 protein binding[16].
  • Insulin receptor substrate 2's molecular function is recorded as phosphatidylinositol 3-kinase binding[17].
  • Insulin receptor substrate 2's cell component is recorded as cytosol[18].
  • Insulin receptor substrate 2's cell component is recorded as plasma membrane[19].
  • Insulin receptor substrate 2's cell component is recorded as cytoplasm[20].
  • Insulin receptor substrate 2's cell component is recorded as protein-containing complex[21].
  • Insulin receptor substrate 2's cell component is recorded as cytosol[22].
  • Insulin receptor substrate 2's cell component is recorded as plasma membrane[23].
  • Insulin receptor substrate 2's biological process is recorded as positive regulation of glucose metabolic process[24].
  • Insulin receptor substrate 2's biological process is recorded as regulation of lipid metabolic process[25].
  • Insulin receptor substrate 2's biological process is recorded as cellular response to insulin stimulus[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . UniProt. Retrieved . wikidata.org.
  2. [3] ↑ . UniProt. Retrieved . wikidata.org.
  3. [4] ↑ . UniProt. Retrieved . wikidata.org.
  4. [5] ↑ . Q20641742. Retrieved . wikidata.org.
  5. [6] ↑ . UniProt. Retrieved . wikidata.org.
  6. [7] ↑ . UniProt. Retrieved . wikidata.org.
  7. [8] ↑ . UniProt. Retrieved . wikidata.org.
  8. [9] ↑ . Insulin signaling and glucose homeostasis in mice lacking protein tyrosine phosphatase alpha. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . CDK4 is an essential insulin effector in adipocytes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . Subcellular localization of insulin receptor substrate family proteins associated with phosphatidylinositol 3-kinase activity and alterations in lipolysis in primary mouse adipocytes from IRS-1 null mice. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] ↑ . CDK4 is an essential insulin effector in adipocytes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] ↑ . Subcellular localization of insulin receptor substrate family proteins associated with phosphatidylinositol 3-kinase activity and alterations in lipolysis in primary mouse adipocytes from IRS-1 null mice. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Insulin receptor substrate 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/insulin-receptor-substrate-2-q21986028
MLA “Insulin receptor substrate 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/insulin-receptor-substrate-2-q21986028.
BibTeX @misc{4ortxyz_insulin-receptor-substrate-2-q21986028_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Insulin receptor substrate 2}}, year = {2026}, url = {https://4ort.xyz/entity/insulin-receptor-substrate-2-q21986028}, note = {Accessed: 2026-05-03}}
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