Insulin receptor substrate 2

mammalian protein found in Homo sapiens
Protein protein Q21173765
Press Enter · cited answer in seconds

Insulin receptor substrate 2

Summary

Insulin receptor substrate 2 is a protein[1].

Key Facts

  • Insulin receptor substrate 2's instance of is recorded as protein[2].
  • Insulin receptor substrate 2's subclass of is recorded as protein[3].
  • Insulin receptor substrate 2's UniProt protein ID is recorded as Q9Y4H2[4].
  • Insulin receptor substrate 2's RefSeq protein ID is recorded as NP_003740[5].
  • Insulin receptor substrate 2's PDB structure ID is recorded as 3FQW[6].
  • Insulin receptor substrate 2's PDB structure ID is recorded as 3FQX[7].
  • Insulin receptor substrate 2's molecular function is recorded as insulin receptor binding[8].
  • Insulin receptor substrate 2's molecular function is recorded as 14-3-3 protein binding[9].
  • Insulin receptor substrate 2's molecular function is recorded as phosphatidylinositol 3-kinase binding[10].
  • Insulin receptor substrate 2's molecular function is recorded as protein binding[11].
  • Insulin receptor substrate 2's molecular function is recorded as protein kinase binding[12].
  • Insulin receptor substrate 2's molecular function is recorded as phosphatidylinositol-4,5-bisphosphate 3-kinase activity[13].
  • Insulin receptor substrate 2's molecular function is recorded as 1-phosphatidylinositol-3-kinase activity[14].
  • Insulin receptor substrate 2's molecular function is recorded as signal transducer activity[15].
  • Insulin receptor substrate 2's molecular function is recorded as protein phosphatase binding[16].
  • Insulin receptor substrate 2's molecular function is recorded as protein domain specific binding[17].
  • Insulin receptor substrate 2's cell component is recorded as cytoplasm[18].
  • Insulin receptor substrate 2's cell component is recorded as cytosol[19].
  • Insulin receptor substrate 2's cell component is recorded as plasma membrane[20].
  • Insulin receptor substrate 2's cell component is recorded as protein-containing complex[21].
  • Insulin receptor substrate 2's biological process is recorded as positive regulation of fatty acid beta-oxidation[22].
  • Insulin receptor substrate 2's biological process is recorded as positive regulation of glucose import[23].
  • Insulin receptor substrate 2's biological process is recorded as positive regulation of glycogen biosynthetic process[24].
  • Insulin receptor substrate 2's biological process is recorded as cellular response to peptide[25].
  • Insulin receptor substrate 2's biological process is recorded as positive regulation of cell migration[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . Q905695. Retrieved . wikidata.org.
  4. [5] . Q20641742. Retrieved . wikidata.org.
  5. [6] . Q905695. Retrieved . wikidata.org.
  6. [7] . Q905695. Retrieved . wikidata.org.
  7. [8] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . Role of IRS-2 in insulin and cytokine signalling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Activation of the insulin receptor by insulin and a synthetic peptide leads to divergent metabolic and mitogenic signaling and responses. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Insulin receptor substrate 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/insulin-receptor-substrate-2
MLA “Insulin receptor substrate 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/insulin-receptor-substrate-2.
BibTeX @misc{4ortxyz_insulin-receptor-substrate-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Insulin receptor substrate 2}}, year = {2026}, url = {https://4ort.xyz/entity/insulin-receptor-substrate-2}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Insulin receptor substrate 2 — https://4ort.xyz/entity/insulin-receptor-substrate-2 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/insulin-receptor-substrate-2 · Last refreshed: