Insulin degrading enzyme

mammalian protein found in Homo sapiens
Protein protein Q1225690
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Summary

Insulin degrading enzyme is a protein[1]. It has Wikipedia articles in 5 language editions, a strong signal of global cultural recognition.[2]

Key Facts

  • Insulin degrading enzyme's instance of is recorded as protein[3].
  • Insulin degrading enzyme's physically interacts with is recorded as Viroporin 3a[4].
  • Insulin degrading enzyme is part of metalloenzyme, LuxS/M16 peptidase-like[5].
  • Insulin degrading enzyme is part of Peptidase M16, N-terminal domain, protein family[6].
  • Insulin degrading enzyme is part of Peptidase M16, middle/third domain, protein family[7].
  • Insulin degrading enzyme is part of Peptidase M16, C-terminal domain, protein family[8].
  • Insulin degrading enzyme is part of Peptidase M16, zinc-binding site, protein family[9].
  • Insulin degrading enzyme comprises Peptidase M16, middle/third domain[10].
  • Insulin degrading enzyme comprises peptidase M16, N-terminal[11].
  • Insulin degrading enzyme comprises peptidase M16, zinc-binding site[12].
  • Insulin degrading enzyme comprises peptidase M16, C-terminal[13].
  • Insulin degrading enzyme's molecular function is recorded as nucleotide binding[14].
  • Insulin degrading enzyme's molecular function is recorded as protein homodimerization activity[15].
  • Insulin degrading enzyme's molecular function is recorded as virus receptor activity[16].
  • Insulin degrading enzyme's molecular function is recorded as peptide binding[17].
  • Insulin degrading enzyme's molecular function is recorded as zinc ion binding[18].
  • Insulin degrading enzyme's molecular function is recorded as amyloid-beta binding[19].
  • Insulin degrading enzyme's molecular function is recorded as insulin binding[20].
  • Insulin degrading enzyme's molecular function is recorded as metal ion binding[21].
  • Insulin degrading enzyme's molecular function is recorded as protein binding[22].
  • Insulin degrading enzyme's molecular function is recorded as peptide hormone binding[23].
  • Insulin degrading enzyme's molecular function is recorded as peptidase activity[24].
  • Insulin degrading enzyme's molecular function is recorded as ATPase activity[25].
  • Insulin degrading enzyme's molecular function is recorded as beta-endorphin binding[26].
  • Insulin degrading enzyme's molecular function is recorded as catalytic activity[27].

Why It Matters

Insulin degrading enzyme has Wikipedia articles in 5 language editions, a strong signal of global cultural recognition.[2] It is known by 6 alternative names across languages and contexts.[28]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . UniProt. Retrieved . wikidata.org.
  2. [4] ↑ . BioGRID. Retrieved . thebiogrid.org. Provenance: wikidata.org.
  3. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . wikidata.org.
  8. [10] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . In vitro degradation of insulin-like peptide 3 by insulin-degrading enzyme. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . In vitro degradation of insulin-like peptide 3 by insulin-degrading enzyme. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . Insulin degrading enzyme is a cellular receptor mediating varicella-zoster virus infection and cell-to-cell spread. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata sitelinks. wikidata.org.
  2. [28] ↑ . Wikidata aliases. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Insulin degrading enzyme. Retrieved October 11, 2026, from https://4ort.xyz/entity/insulin-degrading-enzyme
MLA “Insulin degrading enzyme.” 4ort.xyz Knowledge Graph, 4ort.xyz, 11 Oct. 2026, https://4ort.xyz/entity/insulin-degrading-enzyme.
BibTeX @misc{4ortxyz_insulin-degrading-enzyme_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Insulin degrading enzyme}}, year = {2026}, url = {https://4ort.xyz/entity/insulin-degrading-enzyme}, note = {Accessed: 2026-10-11}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Insulin degrading enzyme — https://4ort.xyz/entity/insulin-degrading-enzyme (retrieved 2026-10-11)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 11w ago · Boghog · 2026-07-22 view diff on Wikidata ↗
    Instance of → —
    Part of → —
    Encoded by → IDE
    Biological process → negative regulation of proteolysis, insulin receptor signaling pathway, insulin metabolic process +27
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 3.4.24.56, #quickstatements; #temporary_batch_1784744182951"
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