Inositol 1,4,5-trisphosphate receptor type 3

mammalian protein found in Homo sapiens

Protein protein Q21107806

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Inositol 1,4,5-trisphosphate receptor type 3

Summary

Inositol 1,4,5-trisphosphate receptor type 3 is a protein^[1].

Key Facts

Inositol 1,4,5-trisphosphate receptor type 3's instance of is recorded as protein^[2].
Inositol 1,4,5-trisphosphate receptor type 3's subclass of is recorded as inositol trisphosphate receptor type 3^[3].
Inositol 1,4,5-trisphosphate receptor type 3's UniProt protein ID is recorded as Meggen^[4].
Inositol 1,4,5-trisphosphate receptor type 3's part of is recorded as Mir domain superfamily^[5].
Inositol 1,4,5-trisphosphate receptor type 3's part of is recorded as RyR/IP3 receptor binding core, RIH domain superfamily^[6].
Inositol 1,4,5-trisphosphate receptor type 3's part of is recorded as inositol 1,4,5-trisphosphate receptors^[7].
Inositol 1,4,5-trisphosphate receptor type 3's part of is recorded as Inositol 1,4,5-trisphosphate/ryanodine receptor domain, protein family^[8].
Inositol 1,4,5-trisphosphate receptor type 3's part of is recorded as Ion transport domain, protein family^[9].
Inositol 1,4,5-trisphosphate receptor type 3's part of is recorded as MIR motif domain, protein family^[10].
Inositol 1,4,5-trisphosphate receptor type 3's part of is recorded as RyR/IP3R Homology associated domain, protein family^[11].
Inositol 1,4,5-trisphosphate receptor type 3's part of is recorded as RIH domain, protein family^[12].
Inositol 1,4,5-trisphosphate receptor type 3's has part is recorded as Ion transport domain^[13].
Inositol 1,4,5-trisphosphate receptor type 3's has part is recorded as MIR motif^[14].
Inositol 1,4,5-trisphosphate receptor type 3's has part is recorded as RyR/IP3R Homology associated domain^[15].
Inositol 1,4,5-trisphosphate receptor type 3's has part is recorded as Inositol 1,4,5-trisphosphate/ryanodine receptor domain^[16].
Inositol 1,4,5-trisphosphate receptor type 3's has part is recorded as RIH domain^[17].
Inositol 1,4,5-trisphosphate receptor type 3's RefSeq protein ID is recorded as NP_002215^[18].
Inositol 1,4,5-trisphosphate receptor type 3's RefSeq protein ID is recorded as XP_011512879^[19].
Inositol 1,4,5-trisphosphate receptor type 3's RefSeq protein ID is recorded as XP_016866321^[20].
Inositol 1,4,5-trisphosphate receptor type 3's PDB structure ID is recorded as 3JRR^[21].
Inositol 1,4,5-trisphosphate receptor type 3's molecular function is recorded as calcium channel activity^[22].
Inositol 1,4,5-trisphosphate receptor type 3's molecular function is recorded as inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity^[23].
Inositol 1,4,5-trisphosphate receptor type 3's molecular function is recorded as ion channel activity^[24].
Inositol 1,4,5-trisphosphate receptor type 3's molecular function is recorded as protein binding^[25].
Inositol 1,4,5-trisphosphate receptor type 3's molecular function is recorded as inositol 1,3,4,5 tetrakisphosphate binding^[26].

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Quick Facts

Instance of protein

Subclass of inositol trisphosphate receptor type 3

Part of Mir domain superfamily, RyR/IP3 receptor binding core, RIH domain superfamily, inositol 1,4,5-trisphosphate receptors, Inositol 1,4,5-trisphosphate/ryanodine receptor domain, protein family, Ion transport domain, protein family, MIR motif domain, protein family, RyR/IP3R Homology associated domain, protein family, RIH domain, protein family

Properties

Biological process sensory perception of umami taste, calcium ion transport into cytosol, regulation of cardiac conduction, regulation of insulin secretion, memory, ion transport, platelet activation, response to calcium ion, sensory perception of bitter taste, calcium ion transmembrane transport, transmembrane transport, sensory perception of sweet taste, inositol phosphate-mediated signaling, calcium ion transport, long-term potentiation, G protein-coupled receptor signaling pathway, positive regulation of cytosolic calcium ion concentration, protein homooligomerization, protein heterooligomerization, release of sequestered calcium ion into cytosol, transport, release of sequestered calcium ion into cytosol

Cell component cytoplasm, integral component of membrane, endoplasmic reticulum membrane, membrane, receptor complex, plasma membrane, apical part of cell, integral component of plasma membrane, nucleoplasm, nucleolus, platelet dense tubular network membrane, endoplasmic reticulum, brush border, nucleus, nuclear outer membrane, myelin sheath, soma, endoplasmic reticulum membrane, plasma membrane, membrane, sarcoplasmic reticulum, cytoplasmic vesicle membrane, secretory granule membrane

Encoded by ITPR3

Found in taxon Homo sapiens

Has part(s) Ion transport domain, MIR motif, RyR/IP3R Homology associated domain, Inositol 1,4,5-trisphosphate/ryanodine receptor domain, RIH domain

Imported from wholeness_audit_2026-05-02

Molecular function calcium channel activity, inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity, ion channel activity, protein binding, inositol 1,3,4,5 tetrakisphosphate binding, calcium-release channel activity, inositol hexakisphosphate binding, inositol 1,4,5 trisphosphate binding, calcium ion binding, phosphatidylinositol binding, inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity, phosphatidylinositol binding, inositol 1,4,5 trisphosphate binding

External References (5)

Ensembl protein id ENSP00000363435, ENSP00000475177

Pdb structure id 3JRR

Refseq protein id NP_002215, XP_011512879, XP_016866321

Transporter classification database id 1.A.3.2.5

Uniprot protein id Meggen

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — subclass of (P279): inositol trisphosphate receptor type 3. wikidata.org.
[4] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — UniProt protein ID (P352): Meggen. Q905695. Retrieved 2019-11-13. wikidata.org.
[5] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — part of (P361): Mir domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — part of (P361): RyR/IP3 receptor binding core, RIH domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — part of (P361): inositol 1,4,5-trisphosphate receptors. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — part of (P361): Inositol 1,4,5-trisphosphate/ryanodine receptor domain, protein family. wikidata.org.
[9] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — part of (P361): Ion transport domain, protein family. wikidata.org.
[10] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — part of (P361): MIR motif domain, protein family. wikidata.org.
[11] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — part of (P361): RyR/IP3R Homology associated domain, protein family. wikidata.org.
[12] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — part of (P361): RIH domain, protein family. wikidata.org.
[13] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — has part(s) (P527): Ion transport domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — has part(s) (P527): MIR motif. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — has part(s) (P527): RyR/IP3R Homology associated domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — has part(s) (P527): Inositol 1,4,5-trisphosphate/ryanodine receptor domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — has part(s) (P527): RIH domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — RefSeq protein ID (P637): NP_002215. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — RefSeq protein ID (P637): XP_011512879. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — RefSeq protein ID (P637): XP_016866321. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — PDB structure ID (P638): 3JRR. Swiss-Prot. Retrieved 2015-11-09. uniprot.org. Provenance: wikidata.org.
[22] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — molecular function (P680): calcium channel activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — molecular function (P680): inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity. GOA. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — molecular function (P680): ion channel activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — molecular function (P680): protein binding. TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Inositol 1,4,5-trisphosphate receptor type 3 — molecular function (P680): inositol 1,3,4,5 tetrakisphosphate binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Inositol 1,4,5-trisphosphate receptor type 3 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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BibTeX

@misc{4ortxyz_inositol-1-4-5-trisphosphate-receptor-type-3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Inositol 1,4,5-trisphosphate receptor type 3}}, year = {2026}, url = {https://4ort.xyz/entity/inositol-1-4-5-trisphosphate-receptor-type-3}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Inositol 1,4,5-trisphosphate receptor type 3 — https://4ort.xyz/entity/inositol-1-4-5-trisphosphate-receptor-type-3 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/inositol-1-4-5-trisphosphate-receptor-type-3 · Last refreshed: May 3, 2026