imipramine
tricyclic antidepressant medication
Facts
14 properties- Instance of
- type of chemical entity
- Subclass of
- chemical compound[10]
- Has use
- medication[11]
- Active ingredient in
- Tofranil
- Canonical SMILES
- CN(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31[8]
- Chemical formula
- C₁₉H₂₄N₂[9]
- LiverTox likelihood score
- LiverTox toxicity likelihood category B
- Mass
- 280.194
- Medical condition treated
- attention deficit hyperactivity disorder, pain, panic disorder, neurotic disorder, depression (1984–present)
- Physically interacts with
- Potassium inwardly-rectifying channel, subfamily J, member 6, Potassium inwardly-rectifying channel, subfamily J, member 5, Potassium voltage-gated channel subfamily H member 1, Cholinergic receptor muscarinic 2, Solute carrier family 6 member 2, solute carrier family 6 member 4[2][3][4][5][6][7]
- Pregnancy category
- Australian pregnancy category C, US pregnancy category N
- Significant drug interaction
- isocarboxazid, phenelzine, procarbazine, (±)-deprenyl, tranylcypromine, loxapine, amitriptyline, (S)-duloxetine, paroxetine, sertraline, fluvoxamine, fluoxetine, nabumetone, naproxen, celecoxib, Diclofenac, piroxicam, meloxicam, (RS)-fenoprofen, (±)-flurbiprofen, ibuprofen, indomethacin, (RS)-ketoprofen, (RS)-etodolac, sulindac, parecoxib, aceclofenac, tenoxicam, (RS)-citalopram, clomipramine, amitriptyline, phenelzine, droperidol, pimozide, haloperidol, quetiapine, verapamil, diltiazem, guanfacine, propranolol, sotalol, labetalol, clonidine, zuclopenthixol, chlorpromazine, clomipramine, clozapine, lithium, droperidol, droperidol, droperidol, droperidol, haloperidol, haloperidol, haloperidol, haloperidol, disopyramide, disopyramide, disopyramide, disopyramide, sotalol, sotalol, sotalol, sotalol, (±)-promethazine, chlorpromazine, clomipramine, pimozide, quetiapine, zuclopenthixol, clozapine, (RS)-hydroxyzine, pethidine, tapentadol, tramadol, fentanyl, phenelzine, phenelzine, phenelzine, phenelzine, linezolid, linezolid, linezolid, linezolid, moclobemide, moclobemide, moclobemide, moclobemide, vortioxetine, vortioxetine, vortioxetine, vortioxetine, nabumetone, naproxen, celecoxib, Diclofenac, piroxicam, meloxicam, (RS)-fenoprofen, (±)-flurbiprofen, ibuprofen, indomethacin, (RS)-ketoprofen, (RS)-etodolac, sulindac, parecoxib, aceclofenac, tenoxicam, norepinephrine, norepinephrine, norepinephrine, epinephrine, epinephrine, epinephrine, propranolol, (RS)-nefopam, (S)-duloxetine, (S)-duloxetine, (S)-duloxetine, paroxetine, bupropion, fluoxetine, loxapine, loxapine, loxapine, loxapine, fluvoxamine, fluvoxamine, fluvoxamine, labetalol, labetalol, labetalol, verapamil, verapamil, verapamil, venlafaxine, venlafaxine, venlafaxine, (RS)-methadone, (RS)-methadone, diltiazem, diltiazem, tryptophan, tryptophan, tryptophan, tryptophan, tryptophan
- Subject has role
- selective serotonin reuptake inhibitor, adrenergic uptake inhibitors, tricyclic antidepressant
- World Health Organisation international non-proprietary name
- imipramine
🏷️ Also known as
en N-(γ-dimethylaminopropyl)iminodibenzyl
en melipramine
en 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine
en N-(gamma-Dimethylaminopropyl)iminodibenzyl
en 3-(5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
en 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine
en imipramine
ar Imipramine
ar إيميبرامين
de Imipramin
el Ιμιπραμίνη
es Tofranil
es imipramina
es Trofanil
fa ایمی پرامین
fa ایمیپرامین
fa ایمیپرامین
fi imipramiini
fi Tofranil
he אימיפראמין
🔖 Identifiers · 48
- OpenAlex ID
- C2779145073
- ATC code
- N06AA02
- CAS Registry Number
- 50-49-7
- ChEBI ID
- 47499
- ChEMBL ID
- CHEMBL11
- ChemSpider ID
- 3568
- DSSTOX compound identifier
- DTXCID9023881
- DSSTox substance ID
- DTXSID1043881
- DeCS ID
- 7280
- DrugBank ID
- DB00458
- DrugCentral ID
- 1427
- EC number
- 200-042-1
Show all 48 identifiers +36
- ECHA Substance Infocard ID
- 100.000.039
- Elhuyar ZTH ID
- 025615
- Encyclopædia Britannica Online ID
- science/imipramine
- Freebase ID
- /m/03ztdf
- Gmelin number
- 1572523
- Guide to Pharmacology Ligand ID
- 357
- HSDB ID
- 3100
- Human Metabolome Database ID
- HMDB0001848
- InChIKey
- BCGWQEUPMDMJNV-UHFFFAOYSA-N
- KEGG ID
- D08070
- LiverTox ID
- Imipramine
- MassBank accession ID
- MSBNK-Athens_Univ-AU150806, MSBNK-Fac_Eng_Univ_Tokyo-JP003874, MSBNK-Waters-WA000794, MSBNK-Waters-WA000795, MSBNK-Waters-WA000796, MSBNK-Waters-WA000797, MSBNK-Waters-WA000798
- MeSH concept ID
- M0011056
- MeSH descriptor ID
- D007099
- MeSH tree code
- D03.633.300.240.485
- MedlinePlus drug identifier
- a682389
- Microsoft Academic ID (discontinued)
- 2779145073
- NDF-RT ID
- N0000147875
- NMRShiftDB structure ID
- 20147315
- NSC number
- 169866
- PDB ligand ID
- IXX
- PDB structure ID
- 2Q72
- Probes And Drugs ID
- PD010016
- PubChem CID
- 3696
- Reaxys registry number
- 256892
- RxNorm CUI
- 5691
- SPLASH
- splash10-0019-7490000000-3fb4d40b6a219f088ec8, splash10-0543-8890000000-6cf8e84f007ce7c750f2, splash10-0ab9-9432000000-033c51459b692622ee7d, splash10-000i-9000000000-eb3c0ecdffc5d9d95e33, splash10-000i-9000000000-55d924fd00e5b357ce9e
- Store medisinske leksikon ID
- imipramin
- SureChEMBL ID
- 34282
- UMLS CUI
- C0020934
- UNII
- OGG85SX4E4
- UniChem compound ID
- 239673
- Wellcome Collection concept ID
- udnjerga
- WikiProjectMed ID
- Imipramine
- WordNet 3.1 Synset ID
- 03567069-n
🔗 Connections
Significant drug interaction 146
lithium,
epinephrine,
epinephrine,
epinephrine,
ibuprofen,
ibuprofen,
norepinephrine,
norepinephrine
+138 more
← Significant drug interaction 142
lithium,
epinephrine,
epinephrine,
epinephrine,
ibuprofen,
ibuprofen,
norepinephrine,
norepinephrine
+134 more
Medical condition treated 4
Subject has role 3
← Drug or therapy used for treatment 3
Has use 1
Physically interacts with 1
Subclass of 1
← Physically interacts with 1
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Summary
imipramine is a type of chemical entity[1].