IGHG1

gene in the species Homo sapiens
Gene gene Q18027713
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Key Facts

  • Part of: Immunoglobulin-like fold[1], Immunoglobulin-like domain superfamily[2]
  • Has part(s): Immunoglobulin/major histocompatibility complex, conserved site[3], immunoglobulin C1-set[4], immunoglobulin-like domain[5]
  • Genomic start: 105736343[6]
  • Genomic end: 105743071[7]
  • Molecular function: antigen binding[8], serine-type endopeptidase activity[9], protein binding[10], immunoglobulin receptor binding[11]
  • Cell component: extracellular region[12], extracellular space[13], plasma membrane[14], external side of plasma membrane[15], membrane[16], immunoglobulin complex, circulating[17], extracellular exosome[18], blood microparticle[19], immunoglobulin complex[20]
  • Biological process: adaptive immune response[21], immune system process[22], proteolysis[23], phagocytosis, recognition[24], phagocytosis, engulfment[25], complement activation[26], complement activation, classical pathway[27], cytokine-mediated signaling pathway[28], regulation of complement activation[29], Fc-gamma receptor signaling pathway involved in phagocytosis[30], defense response to bacterium[31], innate immune response[32], B cell receptor signaling pathway[33], positive regulation of B cell activation[34]
  • Found in taxon: Homo sapiens[35]
  • Chromosome: human chromosome 14[36]
  • Strand orientation: reverse strand[37]
  • Exact match: http://identifiers.org/ncbigene/3500[38]
  • Cytogenetic location: 14q32.33[39]
  • Expressed in: spleen[40], lymph node[41], appendix[42], bone marrow cell[43], gallbladder[44], olfactory zone of nasal mucosa[45], duodenum[46], right coronary artery[47], rectum[48], upper lobe of left lung[49]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [1] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [2] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [6] ↑ . ensembl Release 106. wikidata.org.
  7. [7] ↑ . ensembl Release 106. wikidata.org.
  8. [8] ↑ . The nucleotide sequence of a human immnnoglobulin Cγlgene. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [10] ↑ . Crystal structure of the HSV-1 Fc receptor bound to Fc reveals a mechanism for antibody bipolar bridging. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [11] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [13] ↑ . Human neutrophils secrete bioactive paucimannosidic proteins from azurophilic granules into pathogen-infected sputum. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [15] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [17] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [18] ↑ . In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [19] ↑ . Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [24] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [25] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [30] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [31] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [32] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [33] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  34. [34] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  35. [35] ↑ . ensembl Release 106. wikidata.org.
  36. [36] ↑ . ensembl Release 106. wikidata.org.
  37. [37] ↑ . ensembl Release 106. wikidata.org.
  38. [38] ↑ . Identifiers.org. ebi.ac.uk. Provenance: wikidata.org.
  39. [39] ↑ . NCBI Gene. Retrieved . wikidata.org.
  40. [40] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  41. [41] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  42. [42] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  43. [43] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  44. [44] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  45. [45] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  46. [46] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  47. [47] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  48. [48] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  49. [49] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.

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APA 4ort.xyz Knowledge Graph. (2026). IGHG1. Retrieved October 26, 2026, from https://4ort.xyz/entity/ighg1
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BibTeX @misc{4ortxyz_ighg1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{IGHG1}}, year = {2026}, url = {https://4ort.xyz/entity/ighg1}, note = {Accessed: 2026-10-26}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 22w ago · Mathieu Kappler · 2026-05-20 view diff on Wikidata ↗
    Hgnc gene symbol → IGHG1
    Exact match → http://identifiers.org/ncbigene/3500
    Biological process → adaptive immune response, immune system process, proteolysis +11
    Omim id → 147100
    + 20 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||gsw */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/32527|batch #32527]]: human gene name and description in Alemannic"
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