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Hydroxysteroid 17-beta dehydrogenase 2

mammalian protein found in Homo sapiens
Protein protein Q21117482
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Summary

Hydroxysteroid 17-beta dehydrogenase 2 is a protein[1]. It is known by 12 alternative names across languages and contexts.[2]

Key Facts

  • Part of: NAD(P)-binding domain superfamily[3], Short-chain dehydrogenase/reductase SDR[4], Short-chain dehydrogenase/reductase, conserved site, protein family[5]
  • Has part(s): Short-chain dehydrogenase/reductase, conserved site[6]
  • EC enzyme number: 1.1.1.239[7]
  • Molecular function: oxidoreductase activity[8], testosterone dehydrogenase (NAD+) activity[9], 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity[10], estradiol 17-beta-dehydrogenase activity[11]
  • Cell component: integral component of membrane[12], endoplasmic reticulum membrane[13], membrane[14]
  • Biological process: in utero embryonic development[15], response to retinoic acid[16], steroid biosynthetic process[17], placenta development[18], lipid metabolism[19], estrogen biosynthetic process[20]
  • Encoded by: HSD17B2[21]
  • Found in taxon: Homo sapiens[22]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . Swiss-Prot. Retrieved . uniprot.org. Provenance: wikidata.org.
  6. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . Regulation of 17-beta hydroxysteroid dehydrogenase type 2 in human placental endothelial cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . Regulation of 17-beta hydroxysteroid dehydrogenase type 2 in human placental endothelial cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . UniProt. Retrieved . wikidata.org.
  20. [22] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Hydroxysteroid 17-beta dehydrogenase 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/hydroxysteroid-17-beta-dehydrogenase-2-q21117482
MLA “Hydroxysteroid 17-beta dehydrogenase 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/hydroxysteroid-17-beta-dehydrogenase-2-q21117482.
BibTeX @misc{4ortxyz_hydroxysteroid-17-beta-dehydrogenase-2-q21117482_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Hydroxysteroid 17-beta dehydrogenase 2}}, year = {2026}, url = {https://4ort.xyz/entity/hydroxysteroid-17-beta-dehydrogenase-2-q21117482}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Hydroxysteroid 17-beta dehydrogenase 2 — https://4ort.xyz/entity/hydroxysteroid-17-beta-dehydrogenase-2-q21117482 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/hydroxysteroid-17-beta-dehydrogenase-2-q21117482 · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Ec enzyme number → 1.1.1.239
    Imported from → —
    Wikidata description → mammalian protein found in Homo sapiens
    Encoded by → HSD17B2
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 1.1.1.62, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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