Hyaluronidase 2

mammalian protein found in Homo sapiens
Protein protein Q21103082
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Hyaluronidase 2

Summary

Hyaluronidase 2 is a protein[1]. It is known by 11 alternative names across languages and contexts.[2]

Key Facts

  • Hyaluronidase 2's instance of is recorded as protein[3].
  • Hyaluronidase 2 is part of hyaluronidase[4].
  • Hyaluronidase 2 is part of glycoside hydrolase superfamily[5].
  • Hyaluronidase 2 is part of TIM barrel[6].
  • Hyaluronidase 2's molecular function is recorded as transcription coactivator activity[7].
  • Hyaluronidase 2's molecular function is recorded as hyaluronoglucuronidase activity[8].
  • Hyaluronidase 2's molecular function is recorded as catalytic activity[9].
  • Hyaluronidase 2's molecular function is recorded as virus receptor activity[10].
  • Hyaluronidase 2's molecular function is recorded as hyalurononglucosaminidase activity[11].
  • Hyaluronidase 2's molecular function is recorded as receptor tyrosine kinase binding[12].
  • Hyaluronidase 2's molecular function is recorded as hydrolase activity, acting on glycosyl bonds[13].
  • Hyaluronidase 2's molecular function is recorded as protein binding[14].
  • Hyaluronidase 2's molecular function is recorded as hyaluronic acid binding[15].
  • Hyaluronidase 2's molecular function is recorded as enzyme binding[16].
  • Hyaluronidase 2's molecular function is recorded as receptor signaling protein tyrosine kinase inhibitor activity[17].
  • Hyaluronidase 2's molecular function is recorded as hydrolase activity[18].
  • Hyaluronidase 2's molecular function is recorded as transforming growth factor beta binding[19].
  • Hyaluronidase 2's cell component is recorded as cytoplasm[20].
  • Hyaluronidase 2's cell component is recorded as cytosol[21].
  • Hyaluronidase 2's cell component is recorded as membrane[22].
  • Hyaluronidase 2's cell component is recorded as anchored component of plasma membrane[23].
  • Hyaluronidase 2's cell component is recorded as Golgi membrane[24].
  • Hyaluronidase 2's cell component is recorded as plasma membrane[25].
  • Hyaluronidase 2's cell component is recorded as endocytic vesicle[26].
  • Hyaluronidase 2's cell component is recorded as microvillus[27].

Why It Matters

Hyaluronidase 2 is known by 11 alternative names across languages and contexts.[2]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] . Ultraviolet‐B Irradiation Induces Differential Regulations of Hyaluronidase Expression and Activity in Normal Human Keratinocytes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] . Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirus. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirus. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . Platelet-derived hyaluronidase 2 cleaves hyaluronan into fragments that trigger monocyte-mediated production of proinflammatory cytokines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirus. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . CD44-dependent intracellular and extracellular catabolism of hyaluronic acid by hyaluronidase-1 and -2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . Hyal2 is a glycosylphosphatidylinositol-anchored, lipid raft-associated hyaluronidase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Hyaluronidase 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/hyaluronidase-2
MLA “Hyaluronidase 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/hyaluronidase-2.
BibTeX @misc{4ortxyz_hyaluronidase-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Hyaluronidase 2}}, year = {2026}, url = {https://4ort.xyz/entity/hyaluronidase-2}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Hyaluronidase 2 — https://4ort.xyz/entity/hyaluronidase-2 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 7w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from
    Encoded by HYAL2
    Wikidata description mammalian protein found in Homo sapiens
    Molecular function transcription coactivator activity, hyaluronoglucuronidase activity, catalytic activity +10
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 3.2.1.35, [[:toollabs:quickstatements/#/batch/261488|batch #261488]]"
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