High mobility group AT-hook 2

mammalian protein found in Mus musculus

Protein protein Q21982345

Press Enter · cited answer in seconds

High mobility group AT-hook 2

Summary

High mobility group AT-hook 2 is a protein^[1].

Key Facts

High mobility group AT-hook 2's instance of is recorded as protein^[2].
High mobility group AT-hook 2's subclass of is recorded as protein^[3].
High mobility group AT-hook 2's UniProt protein ID is recorded as P52927^[4].
High mobility group AT-hook 2's part of is recorded as hgh mobility group protein HMGA^[5].
High mobility group AT-hook 2's part of is recorded as AT hook, DNA-binding motif, protein family^[6].
High mobility group AT-hook 2's has part is recorded as AT hook, DNA-binding motif^[7].
High mobility group AT-hook 2's RefSeq protein ID is recorded as NP_001334099^[8].
High mobility group AT-hook 2's RefSeq protein ID is recorded as NP_034571^[9].
High mobility group AT-hook 2's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[10].
High mobility group AT-hook 2's molecular function is recorded as DNA-binding transcription repressor activity, RNA polymerase II-specific^[11].
High mobility group AT-hook 2's molecular function is recorded as nucleosomal DNA binding^[12].
High mobility group AT-hook 2's molecular function is recorded as cAMP response element binding^[13].
High mobility group AT-hook 2's molecular function is recorded as DNA-dependent protein kinase activity^[14].
High mobility group AT-hook 2's molecular function is recorded as MH1 domain binding^[15].
High mobility group AT-hook 2's molecular function is recorded as minor groove of adenine-thymine-rich DNA binding^[16].
High mobility group AT-hook 2's molecular function is recorded as C2H2 zinc finger domain binding^[17].
High mobility group AT-hook 2's molecular function is recorded as protein binding^[18].
High mobility group AT-hook 2's molecular function is recorded as DNA-(apurinic or apyrimidinic site) endonuclease activity^[19].
High mobility group AT-hook 2's molecular function is recorded as DNA binding, bending^[20].
High mobility group AT-hook 2's molecular function is recorded as DNA binding^[21].
High mobility group AT-hook 2's molecular function is recorded as 5'-deoxyribose-5-phosphate lyase activity^[22].
High mobility group AT-hook 2's molecular function is recorded as MH2 domain binding^[23].
High mobility group AT-hook 2's molecular function is recorded as enzyme binding^[24].
High mobility group AT-hook 2's cell component is recorded as nuclear chromosome^[25].
High mobility group AT-hook 2's cell component is recorded as chromatin^[26].

⭐ Popularity Graph

0/100 long tail

Quick Facts

Instance of protein

Subclass of protein

Part of hgh mobility group protein HMGA, AT hook, DNA-binding motif, protein family

Properties

Biological process positive regulation of transcription regulatory region DNA binding, endodermal cell differentiation, negative regulation of DNA binding, negative regulation of Wnt signaling pathway, mesenchymal cell differentiation, positive regulation of cellular senescence, spermatogenesis, positive regulation of multicellular organism growth, cell cycle, cell population proliferation, mitotic G2 DNA damage checkpoint signaling, regulation of peptide hormone secretion, lung epithelium development, cell proliferation in forebrain, chromosome breakage, fat pad development, negative regulation of astrocyte differentiation, regulation of transcription, DNA-templated, regulation of stem cell population maintenance, transcription, DNA-templated, negative regulation of double-strand break repair via nonhomologous end joining, positive regulation of response to DNA damage stimulus, regulation of cell cycle process, male gonad development, positive regulation of epithelial cell proliferation involved in lung morphogenesis, chondrocyte differentiation, regulation of cellular response to drug, negative regulation of apoptotic process, heterochromatin assembly, oncogene-induced cell senescence, negative regulation by host of viral transcription, regulation of growth hormone secretion, meiosis, chondrocyte proliferation, epithelial to mesenchymal transition, adipose tissue development, negative regulation of transcription, DNA-templated, positive regulation of stem cell proliferation, fat cell differentiation, pituitary gland development, mitotic cell cycle, somatic stem cell population maintenance, positive regulation of cellular response to X-ray, adrenal gland development, cell division, positive regulation of gene expression, chromosome condensation, positive regulation of cell population proliferation, positive regulation of apoptotic process, mesodermal cell differentiation, regulation of growth, epithelial tube branching involved in lung morphogenesis, base-excision repair, positive regulation of transcription by RNA polymerase II, negative regulation of single stranded viral RNA replication via double stranded DNA intermediate, mesodermal-endodermal cell signaling, positive regulation of DNA-binding transcription factor activity, negative regulation of transcription by RNA polymerase II, negative regulation of intracellular steroid hormone receptor signaling pathway, transcription by RNA polymerase II, negative regulation of receptor signaling pathway via JAK-STAT, signal transduction

Cell component nuclear chromosome, chromatin, SMAD protein complex, senescence-associated heterochromatin focus, protein-DNA complex, nucleus

Encoded by Hmga2

Found in taxon house mouse

Has part(s) AT hook, DNA-binding motif

Imported from wholeness_audit_2026-05-02

Molecular function DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, nucleosomal DNA binding, cAMP response element binding, DNA-dependent protein kinase activity, MH1 domain binding, minor groove of adenine-thymine-rich DNA binding, C2H2 zinc finger domain binding, protein binding, DNA-(apurinic or apyrimidinic site) endonuclease activity, DNA binding, bending, DNA binding, 5'-deoxyribose-5-phosphate lyase activity, MH2 domain binding, enzyme binding

External References (3)

Ensembl protein id ENSMUSP00000072556, ENSMUSP00000123998

Refseq protein id NP_001334099, NP_034571

Uniprot protein id P52927

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ High mobility group AT-hook 2 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ High mobility group AT-hook 2 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ High mobility group AT-hook 2 — UniProt protein ID (P352): P52927. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ High mobility group AT-hook 2 — part of (P361): hgh mobility group protein HMGA. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ High mobility group AT-hook 2 — part of (P361): AT hook, DNA-binding motif, protein family. wikidata.org.
[7] ↑ High mobility group AT-hook 2 — has part(s) (P527): AT hook, DNA-binding motif. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ High mobility group AT-hook 2 — RefSeq protein ID (P637): NP_001334099. Q20641742. Retrieved 2022-03-20. wikidata.org.
[9] ↑ High mobility group AT-hook 2 — RefSeq protein ID (P637): NP_034571. Q20641742. Retrieved 2022-03-20. wikidata.org.
[10] ↑ High mobility group AT-hook 2 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. Q905695. Retrieved 2016-08-09. wikidata.org.
[11] ↑ High mobility group AT-hook 2 — molecular function (P680): DNA-binding transcription repressor activity, RNA polymerase II-specific. Q905695. Retrieved 2016-08-09. wikidata.org.
[12] ↑ High mobility group AT-hook 2 — molecular function (P680): nucleosomal DNA binding. Q905695. Retrieved 2016-08-09. wikidata.org.
[13] ↑ High mobility group AT-hook 2 — molecular function (P680): cAMP response element binding. Q905695. Retrieved 2016-08-09. wikidata.org.
[14] ↑ High mobility group AT-hook 2 — molecular function (P680): DNA-dependent protein kinase activity. Q905695. Retrieved 2016-08-09. wikidata.org.
[15] ↑ High mobility group AT-hook 2 — molecular function (P680): MH1 domain binding. Q905695. Retrieved 2016-08-09. wikidata.org.
[16] ↑ High mobility group AT-hook 2 — molecular function (P680): minor groove of adenine-thymine-rich DNA binding. Q905695. Retrieved 2016-08-09. wikidata.org.
[17] ↑ High mobility group AT-hook 2 — molecular function (P680): C2H2 zinc finger domain binding. Q905695. Retrieved 2016-08-09. wikidata.org.
[18] ↑ High mobility group AT-hook 2 — molecular function (P680): protein binding. Q905695. Retrieved 2016-08-09. wikidata.org.
[19] ↑ High mobility group AT-hook 2 — molecular function (P680): DNA-(apurinic or apyrimidinic site) endonuclease activity. Q905695. Retrieved 2016-08-09. wikidata.org.
[20] ↑ High mobility group AT-hook 2 — molecular function (P680): DNA binding, bending. Q905695. Retrieved 2016-08-09. wikidata.org.
[21] ↑ High mobility group AT-hook 2 — molecular function (P680): DNA binding. Q905695. Retrieved 2016-08-09. wikidata.org.
[22] ↑ High mobility group AT-hook 2 — molecular function (P680): 5'-deoxyribose-5-phosphate lyase activity. Q905695. Retrieved 2016-08-09. wikidata.org.
[23] ↑ High mobility group AT-hook 2 — molecular function (P680): MH2 domain binding. Q905695. Retrieved 2016-08-09. wikidata.org.
[24] ↑ High mobility group AT-hook 2 — molecular function (P680): enzyme binding. Q905695. Retrieved 2016-08-09. wikidata.org.
[25] ↑ High mobility group AT-hook 2 — cell component (P681): nuclear chromosome. Large-scale identification of mammalian proteins localized to nuclear sub-compartments. Retrieved 2017-09-16. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ High mobility group AT-hook 2 — cell component (P681): chromatin. GOA. Retrieved 2017-09-16. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ High mobility group AT-hook 2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). High mobility group AT-hook 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/high-mobility-group-at-hook-2-q21982345

MLA

“High mobility group AT-hook 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/high-mobility-group-at-hook-2-q21982345.

BibTeX

@misc{4ortxyz_high-mobility-group-at-hook-2-q21982345_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{High mobility group AT-hook 2}}, year = {2026}, url = {https://4ort.xyz/entity/high-mobility-group-at-hook-2-q21982345}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): High mobility group AT-hook 2 — https://4ort.xyz/entity/high-mobility-group-at-hook-2-q21982345 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/high-mobility-group-at-hook-2-q21982345 · Last refreshed: May 3, 2026