Hepcidin antimicrobial peptide

mammalian protein found in Mus musculus
Protein protein Q21981175
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Hepcidin antimicrobial peptide

Summary

Hepcidin antimicrobial peptide is a protein[1].

Key Facts

  • Hepcidin antimicrobial peptide's instance of is recorded as protein[2].
  • Hepcidin antimicrobial peptide's subclass of is recorded as protein[3].
  • Hepcidin antimicrobial peptide's UniProt protein ID is recorded as Q9EQ21[4].
  • Hepcidin antimicrobial peptide's part of is recorded as Hepcidins[5].
  • Hepcidin antimicrobial peptide's part of is recorded as auxiliary protein involved in transmembrane transport[6].
  • Hepcidin antimicrobial peptide's RefSeq protein ID is recorded as NP_115930[7].
  • Hepcidin antimicrobial peptide's molecular function is recorded as copper ion binding[8].
  • Hepcidin antimicrobial peptide's molecular function is recorded as hormone activity[9].
  • Hepcidin antimicrobial peptide's cell component is recorded as extracellular region[10].
  • Hepcidin antimicrobial peptide's cell component is recorded as nucleus[11].
  • Hepcidin antimicrobial peptide's cell component is recorded as extracellular space[12].
  • Hepcidin antimicrobial peptide's cell component is recorded as extracellular space[13].
  • Hepcidin antimicrobial peptide's biological process is recorded as cellular response to extracellular stimulus[14].
  • Hepcidin antimicrobial peptide's biological process is recorded as myeloid cell homeostasis[15].
  • Hepcidin antimicrobial peptide's biological process is recorded as iron ion homeostasis[16].
  • Hepcidin antimicrobial peptide's biological process is recorded as receptor signaling pathway via JAK-STAT[17].
  • Hepcidin antimicrobial peptide's biological process is recorded as positive regulation of macrophage activation[18].
  • Hepcidin antimicrobial peptide's biological process is recorded as negative regulation of transcription by RNA polymerase II[19].
  • Hepcidin antimicrobial peptide's biological process is recorded as defense response to bacterium[20].
  • Hepcidin antimicrobial peptide's biological process is recorded as negative regulation of inflammatory response[21].
  • Hepcidin antimicrobial peptide's biological process is recorded as defense response to fungus[22].
  • Hepcidin antimicrobial peptide's biological process is recorded as positive regulation of transcription by RNA polymerase II[23].
  • Hepcidin antimicrobial peptide's biological process is recorded as cellular iron ion homeostasis[24].
  • Hepcidin antimicrobial peptide's biological process is recorded as negative regulation of bone resorption[25].
  • Hepcidin antimicrobial peptide's biological process is recorded as negative regulation of iron ion transmembrane transport[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . Q905695. Retrieved . wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . Retrieved . wikidata.org.
  6. [7] . Q20641742. Retrieved . wikidata.org.
  7. [8] . Characterization of the transition-metal-binding properties of hepcidin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . Quantitation of hepcidin from human and mouse serum using liquid chromatography tandem mass spectrometry. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . Bmp6 expression in murine liver non parenchymal cells: a mechanism to control their high iron exporter activity and protect hepatocytes from iron overload?. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Role of hepcidin in the setting of hypoferremia during acute inflammation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . Hepcidin destabilizes atherosclerotic plaque via overactivating macrophages after erythrophagocytosis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . Suppression of hepcidin expression and iron overload mediate Salmonella susceptibility in ankyrin 1 ENU-induced mutant. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . Structure and exon to protein domain relationships of the mouse carbonic anhydrase II gene. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . Hepcidin deficiency undermines bone load-bearing capacity through inducing iron overload. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblasts. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Hepcidin antimicrobial peptide. Retrieved May 3, 2026, from https://4ort.xyz/entity/hepcidin-antimicrobial-peptide-q21981175
MLA “Hepcidin antimicrobial peptide.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/hepcidin-antimicrobial-peptide-q21981175.
BibTeX @misc{4ortxyz_hepcidin-antimicrobial-peptide-q21981175_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Hepcidin antimicrobial peptide}}, year = {2026}, url = {https://4ort.xyz/entity/hepcidin-antimicrobial-peptide-q21981175}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Hepcidin antimicrobial peptide — https://4ort.xyz/entity/hepcidin-antimicrobial-peptide-q21981175 (retrieved 2026-05-03)

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