Glycyl-tRNA synthetase 1

mammalian protein found in Homo sapiens
Protein protein Q5572591
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Summary

Glycyl-tRNA synthetase 1 is a protein[1]. It is known by 13 alternative names across languages and contexts.[2]

Key Facts

  • Part of: Glycyl-tRNA synthetase[3], Anticodon-binding domain superfamily[4], S15/NS1, RNA-binding[5], Aminoacyl-tRNA synthetase, class II (G/ P/ S/T), protein family[6], Glycyl-tRNA synthetase-like core domain, protein family[7], Aminoacyl tRNA synthetases, class II[8], WHEP-TRS domain, protein family[9]
  • Has part(s): Glycyl-tRNA synthetase-like core domain[10], Anticodon-binding[11], WHEP-TRS domain[12], Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)[13], Aminoacyl-tRNA synthetase, class II domain[14]
  • Molecular function: aminoacyl-tRNA ligase activity[15], nucleotide binding[16], ligase activity[17], protein dimerization activity[18], ATP binding[19], bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity[20], hydrolase activity[21], protein binding[22], identical protein binding[23], glycine-tRNA ligase activity[24], transferase activity[25]
  • Cell component: axon[26], mitochondrial matrix[27], cell projection[28], secretory granule[29], cytosol[30], extracellular exosome[31], extracellular region[32], cytoplasm[33], mitochondrion[34]
  • Biological process: diadenosine tetraphosphate biosynthetic process[35], protein biosynthesis[36], glycyl-tRNA aminoacylation[37], mitochondrial glycyl-tRNA aminoacylation[38], tRNA aminoacylation for protein translation[39]
  • Encoded by: GARS1[40]
  • Found in taxon: Homo sapiens[41]
  • Exact match: http://purl.uniprot.org/uniprot/P41250[42]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . wikidata.org.
  8. [10] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . Charcot-Marie-Tooth disease-associated mutant tRNA synthetases linked to altered dimer interface and neurite distribution defect.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Charcot-Marie-Tooth disease-associated mutant tRNA synthetases linked to altered dimer interface and neurite distribution defect.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . Primary structure and functional expression of human Glycyl-tRNA synthetase, an autoantigen in myositis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . Crystal structures and biochemical analyses suggest a unique mechanism and role for human glycyl-tRNA synthetase in Ap4A homeostasis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  34. [36] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  35. [37] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  36. [38] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  37. [39] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  38. [40] ↑ . UniProt. Retrieved . wikidata.org.
  39. [41] ↑ . UniProt. Retrieved . wikidata.org.
  40. [42] ↑ . Identifiers.org. wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Glycyl-tRNA synthetase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/glycyl-trna-synthetase-1
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BibTeX @misc{4ortxyz_glycyl-trna-synthetase-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Glycyl-tRNA synthetase 1}}, year = {2026}, url = {https://4ort.xyz/entity/glycyl-trna-synthetase-1}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-23 view diff on Wikidata ↗
    Uniprot protein id → P41250
    Umls cui → C0017983
    Exact match → http://purl.uniprot.org/uniprot/P41250
    Imported from → —
    + 16 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 6.1.1.14, [[:toollabs:quickstatements/#/batch/261457|batch #261457]]"
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