Glial cell derived neurotrophic factor

mammalian protein found in Homo sapiens
Protein protein Q3064188
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Glial cell derived neurotrophic factor

Summary

Glial cell derived neurotrophic factor is a protein[1].

Key Facts

  • Glial cell derived neurotrophic factor's instance of is recorded as protein[2].
  • Glial cell derived neurotrophic factor is part of glial cell line-derived neurotrophic factor[3].
  • Glial cell derived neurotrophic factor is part of Cystine-knot cytokine[4].
  • Glial cell derived neurotrophic factor is part of Transforming growth factor-beta, C-terminal domain, protein family[5].
  • Glial cell derived neurotrophic factor comprises Transforming growth factor-beta, C-terminal[6].
  • Glial cell derived neurotrophic factor's molecular function is recorded as protein homodimerization activity[7].
  • Glial cell derived neurotrophic factor's molecular function is recorded as protein binding[8].
  • Glial cell derived neurotrophic factor's molecular function is recorded as growth factor activity[9].
  • Glial cell derived neurotrophic factor's molecular function is recorded as signaling receptor binding[10].
  • Glial cell derived neurotrophic factor's molecular function is recorded as chemoattractant activity involved in axon guidance[11].
  • Glial cell derived neurotrophic factor's molecular function is recorded as growth factor activity[12].
  • Glial cell derived neurotrophic factor's cell component is recorded as extracellular region[13].
  • Glial cell derived neurotrophic factor's cell component is recorded as intracellular anatomical structure[14].
  • Glial cell derived neurotrophic factor's cell component is recorded as extracellular space[15].
  • Glial cell derived neurotrophic factor's biological process is recorded as peristalsis[16].
  • Glial cell derived neurotrophic factor's biological process is recorded as ureteric bud development[17].
  • Glial cell derived neurotrophic factor's biological process is recorded as regulation of dopamine uptake involved in synaptic transmission[18].
  • Glial cell derived neurotrophic factor's biological process is recorded as peripheral nervous system development[19].
  • Glial cell derived neurotrophic factor's biological process is recorded as sympathetic nervous system development[20].
  • Glial cell derived neurotrophic factor's biological process is recorded as organ induction[21].
  • Glial cell derived neurotrophic factor's biological process is recorded as adult locomotory behavior[22].
  • Glial cell derived neurotrophic factor's biological process is recorded as positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis[23].
  • Glial cell derived neurotrophic factor's biological process is recorded as regulation of stem cell differentiation[24].
  • Glial cell derived neurotrophic factor's biological process is recorded as regulation of morphogenesis of a branching structure[25].
  • Glial cell derived neurotrophic factor's biological process is recorded as mesenchymal to epithelial transition involved in metanephros morphogenesis[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [8] . A proteome-scale map of the human interactome network. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . Binding of GDNF and neurturin to human GDNF family receptor alpha 1 and 2. Influence of cRET and cooperative interactions. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . gdnf activates midline repulsion by Semaphorin3B via NCAM during commissural axon guidance. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . Glial cell line-derived neurotrophic factor up-regulates the expression of tyrosine hydroxylase gene in human neuroblastoma cell lines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Calcitriol Imparts Neuroprotection In Vitro to Midbrain Dopaminergic Neurons by Upregulating GDNF Expression. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Glial cell derived neurotrophic factor. Retrieved May 3, 2026, from https://4ort.xyz/entity/glial-cell-derived-neurotrophic-factor
MLA “Glial cell derived neurotrophic factor.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/glial-cell-derived-neurotrophic-factor.
BibTeX @misc{4ortxyz_glial-cell-derived-neurotrophic-factor_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Glial cell derived neurotrophic factor}}, year = {2026}, url = {https://4ort.xyz/entity/glial-cell-derived-neurotrophic-factor}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Glial cell derived neurotrophic factor — https://4ort.xyz/entity/glial-cell-derived-neurotrophic-factor (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 18d ago · Twofivesixbot bot · 2026-05-19 view diff on Wikidata ↗
    Instance of protein
    Wikidata description mammalian protein found in Homo sapiens
    Molecular function protein homodimerization activity, protein binding, growth factor activity +3
    Encoded by GDNF
    + 13 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-update-qualifiers:1||1|6 */ [[Property:P2347]]: 38878, mv to monolingual text names on YSO statements"
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