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givinostat

chemical compound
Class type of: anti-inflammatory drug, angiogenesis inhibitor Q426257

Facts

10 properties
Instance of
type of chemical entity
Subclass of
anti-inflammatory drug, angiogenesis inhibitor[13][14]
Has use
medication[15]
Canonical SMILES
CCN(CC)CC1=CC2=C(C=C1)C=C(C=C2)COC(=O)NC3=CC=C(C=C3)C(=O)NO[11]
Chemical formula
C₂₄H₂₇N₃O₄[12]
Inhibitor of
growth, growth[20]
Mass
+421.200156[17]
Physically interacts with
histone deacetylase 1, histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 4, Histone deacetylase 5, Histone deacetylase 6, Histone deacetylase 7, Histone deacetylase 8, Histone deacetylase 9[2][3][4][5][6][7][8][9][10]
Route of administration
oral administration[16]
World Health Organisation international non-proprietary name
givinostat, givinostatum[18][19]
🏷️ Also known as
en {6-[(diethylamino)methyl]naphthalen-2-yl}methyl [4-(hydroxycarbamoyl)phenyl]carbamate en gavinostat en givinostat en Givinostat en ITF-2357 en ITF2357 fa جیوینوستات ja ジビノスタット pt Gavinostat
🔖 Identifiers · 23
CAS Registry Number
497833-27-9
ChEBI ID
94187
ChEMBL ID
CHEMBL1213492
ChemSpider ID
7980752
DSSTOX compound identifier
DTXCID50120540
DSSTox substance ID
DTXSID70198049
DrugBank ID
DB12645
EC number
823-729-3
ECHA Substance Infocard ID
100.258.524
Freebase ID
/m/0ddbwzg
Guide to Pharmacology Ligand ID
7490
Human Metabolome Database ID
HMDB0252732
Show all 23 identifiers +11
InChI
InChI=1S/C24H27N3O4/c1-3-27(4-2)15-17-5-7-21-14-18(6-8-20(21)13-17)16-31-24(29)25-22-11-9-19(10-12-22)23(28)26-30/h5-14,30H,3-4,15-16H2,1-2H3,(H,25,29)(H,26,28)
InChIKey
YALNUENQHAQXEA-UHFFFAOYSA-N
Microsoft Academic ID (discontinued)
2776414255
PDB ligand ID
QCM
Probes And Drugs ID
PD046520
PubChem CID
9804992
SureChEMBL ID
1555814
UK Parliament thesaurus ID
551799
UNII
5P60F84FBH
UniChem compound ID
651980
World Health Organisation international non-proprietary name numeric ID
9132

Report an error or request removal Lineage (PROV-JSON)

🔗 Connections
Inhibitor of 2
growth, growth
Has use 1
medication
Physically interacts with 1
Histone deacetylase 4
Route of administration 1
oral administration
Subclass of 1
angiogenesis inhibitor
← FactGrid item ID 1
Udvar
← Physically interacts with 1
Histone deacetylase 4
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Summary

givinostat is a type of chemical entity[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  2. [3] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [4] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  4. [5] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  5. [6] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  6. [7] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  7. [8] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  8. [9] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  9. [10] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  10. [11] ↑ . PubChem. Retrieved . wikidata.org.
  11. [12] ↑ . PubChem. Retrieved . wikidata.org.
  12. [13] ↑ . PubChem. Retrieved . wikidata.org.
  13. [14] ↑ . PubChem. Retrieved . wikidata.org.
  14. [15] ↑ . wikidata.org.
  15. [16] ↑ . Calibr ReFrame Drug repurposing library. Retrieved . wikidata.org.
  16. [17] ↑ . PubChem. Retrieved . wikidata.org.
  17. [18] ↑ . Recommended INN: List 63. wikidata.org.
  18. [19] ↑ . Recommended INN: List 63. wikidata.org.
  19. [20] ↑ . Calibr ReFrame Drug repurposing library. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). givinostat. Retrieved November 10, 2026, from https://4ort.xyz/entity/givinostat
MLA “givinostat.” 4ort.xyz Knowledge Graph, 4ort.xyz, 10 Nov. 2026, https://4ort.xyz/entity/givinostat.
BibTeX @misc{4ortxyz_givinostat_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{givinostat}}, year = {2026}, url = {https://4ort.xyz/entity/givinostat}, note = {Accessed: 2026-11-10}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): givinostat — https://4ort.xyz/entity/givinostat (retrieved 2026-11-10)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 20w ago · Nabbegat · 2026-06-19 view diff on Wikidata ↗
    Instance of → type of chemical entity
    Subclass of → anti-inflammatory drug, angiogenesis inhibitor
    Inhibitor of → growth
    Physically interacts with → histone deacetylase 1, histone deacetylase 2, Histone deacetylase 3 +1
    + 3 other properties edited (see Wikidata diff for full list)
    "Changed [tr] labels, descriptions or aliases: QuickStatements 3.0 batch #37300"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.