General transcription factor IIH subunit 2

mammalian protein found in Homo sapiens

Protein protein Q22676916

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Summary

General transcription factor IIH subunit 2 is a protein^[1].

Key Facts

General transcription factor IIH subunit 2's instance of is recorded as protein^[2].
General transcription factor IIH subunit 2's subclass of is recorded as protein^[3].
General transcription factor IIH subunit 2's UniProt protein ID is recorded as Luchino Visconti^[4].
General transcription factor IIH subunit 2's part of is recorded as TFIIH subunit Ssl1/p44^[5].
General transcription factor IIH subunit 2's part of is recorded as von Willebrand factor A-like domain superfamily^[6].
General transcription factor IIH subunit 2's part of is recorded as Zinc finger, RING/FYVE/PHD-type^[7].
General transcription factor IIH subunit 2's part of is recorded as Zinc finger C2H2-type, protein family^[8].
General transcription factor IIH subunit 2's part of is recorded as von Willebrand factor, type A, protein family^[9].
General transcription factor IIH subunit 2's part of is recorded as Ssl1-like domain, protein family^[10].
General transcription factor IIH subunit 2's part of is recorded as TFIIH C1-like domain, protein family^[11].
General transcription factor IIH subunit 2's has part is recorded as Ssl1-like^[12].
General transcription factor IIH subunit 2's has part is recorded as TFIIH C1-like domain^[13].
General transcription factor IIH subunit 2's has part is recorded as von Willebrand factor, type A^[14].
General transcription factor IIH subunit 2's has part is recorded as Zinc finger C2H2-type^[15].
General transcription factor IIH subunit 2's RefSeq protein ID is recorded as NP_001506^[16].
General transcription factor IIH subunit 2's RefSeq protein ID is recorded as XP_016864892^[17].
General transcription factor IIH subunit 2's RefSeq protein ID is recorded as XP_016864893^[18].
General transcription factor IIH subunit 2's RefSeq protein ID is recorded as XP_016864895^[19].
General transcription factor IIH subunit 2's RefSeq protein ID is recorded as XP_024301805^[20].
General transcription factor IIH subunit 2's RefSeq protein ID is recorded as NP_001351496^[21].
General transcription factor IIH subunit 2's RefSeq protein ID is recorded as NP_001351497^[22].
General transcription factor IIH subunit 2's RefSeq protein ID is recorded as NP_001351498^[23].
General transcription factor IIH subunit 2's RefSeq protein ID is recorded as NP_001351499^[24].
General transcription factor IIH subunit 2's RefSeq protein ID is recorded as NP_001351500^[25].
General transcription factor IIH subunit 2's RefSeq protein ID is recorded as NP_001351501^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of TFIIH subunit Ssl1/p44, von Willebrand factor A-like domain superfamily, Zinc finger, RING/FYVE/PHD-type, Zinc finger C2H2-type, protein family, von Willebrand factor, type A, protein family, Ssl1-like domain, protein family, TFIIH C1-like domain, protein family

Properties

Biological process termination of RNA polymerase I transcription, G protein-coupled receptor internalization, regulation of transcription, DNA-templated, transcription initiation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, 7-methylguanosine mRNA capping, transcription by RNA polymerase II, transcription, DNA-templated, cellular response to DNA damage stimulus, global genome nucleotide-excision repair, transcription-coupled nucleotide-excision repair, transcription initiation from RNA polymerase II promoter, nucleotide-excision repair, DNA incision, response to UV, nucleotide-excision repair, preincision complex assembly, DNA repair, protein biosynthesis, nucleotide-excision repair, DNA incision, 5'-to lesion, nucleotide-excision repair, preincision complex stabilization, protein phosphorylation, nucleotide-excision repair, regulation of transcription by RNA polymerase II, positive regulation of DNA helicase activity, nucleotide-excision repair, DNA duplex unwinding, nucleotide-excision repair, DNA incision, 3'-to lesion, transcription elongation from RNA polymerase I promoter

Cell component nucleoplasm, transcription factor TFIIH holo complex, transcription factor TFIIH core complex, core TFIIH complex portion of holo TFIIH complex, nucleus, transcription factor TFIID complex, nuclear speck, transcription factor TFIIH core complex, transcription factor TFIIH holo complex

Encoded by GTF2H2

Found in taxon Homo sapiens

Has part(s) Ssl1-like, TFIIH C1-like domain, von Willebrand factor, type A, Zinc finger C2H2-type

Imported from wholeness_audit_2026-05-02

Molecular function protein kinase activity, ATP-dependent activity, acting on DNA, protein N-terminus binding, DNA-binding transcription factor activity, zinc ion binding, translation factor activity, RNA binding, metal ion binding, protein binding, RNA polymerase II CTD heptapeptide repeat kinase activity, nucleic acid binding, nucleic acid binding, RNA polymerase II general transcription initiation factor activity

External References (4)

Ensembl protein id ENSP00000274400, ENSP00000328901, ENSP00000480548, ENSP00000479262, ENSP00000477954, ENSP00000486014, ENSP00000480983, ENSP00000479821, ENSP00000473333, ENSP00000473362, ENSP00000394164, ENSP00000480417, ENSP00000483350, ENSP00000487533, ENSP00000429057, ENSP00000487055, ENSP00000428718, ENSP00000485816

Pdb structure id 1Z60, 5IVW, 5IY9, 5IY8, 5IY7, 5IY6

Refseq protein id NP_001506, XP_016864892, XP_016864893, XP_016864895, XP_024301805, NP_001351496, NP_001351497, NP_001351498, NP_001351499, NP_001351500, NP_001351501, NP_001351502

Uniprot protein id Luchino Visconti

🏷️ Also known as

en basic transcription factor 2 44 kDa subunit en BTF2 p44 en general transcription factor IIH polypeptide 2 en general transcription factor IIH, polypeptide 2, 44kDa en general transcription factor IIH, polypeptide 2, 44kD subunit en General transcription factor IIH subunit 2 en GTF2H2 en TFIIH basal transcription factor complex p44 subunit

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ General transcription factor IIH subunit 2 — instance of (P31): protein. UniProt. Retrieved 2019-11-13. wikidata.org.
[3] ↑ General transcription factor IIH subunit 2 — subclass of (P279): protein. UniProt. Retrieved 2016-12-01. wikidata.org.
[4] ↑ General transcription factor IIH subunit 2 — UniProt protein ID (P352): Luchino Visconti. UniProt. Retrieved 2019-11-13. wikidata.org.
[5] ↑ General transcription factor IIH subunit 2 — part of (P361): TFIIH subunit Ssl1/p44. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ General transcription factor IIH subunit 2 — part of (P361): von Willebrand factor A-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ General transcription factor IIH subunit 2 — part of (P361): Zinc finger, RING/FYVE/PHD-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ General transcription factor IIH subunit 2 — part of (P361): Zinc finger C2H2-type, protein family. wikidata.org.
[9] ↑ General transcription factor IIH subunit 2 — part of (P361): von Willebrand factor, type A, protein family. wikidata.org.
[10] ↑ General transcription factor IIH subunit 2 — part of (P361): Ssl1-like domain, protein family. wikidata.org.
[11] ↑ General transcription factor IIH subunit 2 — part of (P361): TFIIH C1-like domain, protein family. wikidata.org.
[12] ↑ General transcription factor IIH subunit 2 — has part(s) (P527): Ssl1-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ General transcription factor IIH subunit 2 — has part(s) (P527): TFIIH C1-like domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ General transcription factor IIH subunit 2 — has part(s) (P527): von Willebrand factor, type A. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ General transcription factor IIH subunit 2 — has part(s) (P527): Zinc finger C2H2-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ General transcription factor IIH subunit 2 — RefSeq protein ID (P637): NP_001506. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ General transcription factor IIH subunit 2 — RefSeq protein ID (P637): XP_016864892. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ General transcription factor IIH subunit 2 — RefSeq protein ID (P637): XP_016864893. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ General transcription factor IIH subunit 2 — RefSeq protein ID (P637): XP_016864895. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ General transcription factor IIH subunit 2 — RefSeq protein ID (P637): XP_024301805. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ General transcription factor IIH subunit 2 — RefSeq protein ID (P637): NP_001351496. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ General transcription factor IIH subunit 2 — RefSeq protein ID (P637): NP_001351497. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ General transcription factor IIH subunit 2 — RefSeq protein ID (P637): NP_001351498. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ General transcription factor IIH subunit 2 — RefSeq protein ID (P637): NP_001351499. Q20641742. Retrieved 2020-05-30. wikidata.org.
[25] ↑ General transcription factor IIH subunit 2 — RefSeq protein ID (P637): NP_001351500. Q20641742. Retrieved 2020-05-30. wikidata.org.
[26] ↑ General transcription factor IIH subunit 2 — RefSeq protein ID (P637): NP_001351501. Q20641742. Retrieved 2020-05-30. wikidata.org.

Class ancestry

[1] ↑ General transcription factor IIH subunit 2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

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BibTeX

@misc{4ortxyz_general-transcription-factor-iih-subunit-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{General transcription factor IIH subunit 2}}, year = {2026}, url = {https://4ort.xyz/entity/general-transcription-factor-iih-subunit-2}, note = {Accessed: 2026-05-03}}

LLM prompt

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