G protein-coupled receptor kinase 3

mammalian protein found in Homo sapiens
Protein protein Q21112691
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Summary

G protein-coupled receptor kinase 3 is a protein[1]. It is known by 6 alternative names across languages and contexts.[2]

Key Facts

  • Physically interacts with: balanol[3]
  • Part of: GPCR kinase[4], Protein kinase-like domain superfamily[5], PH-like domain superfamily[6], RGS domain superfamily[7], pleckstrin homology domain, protein family[8], regulator of G protein signalling[9], AGC-kinase, C-terminal domain, protein family[10], Protein kinase domain, protein family[11], Protein kinase, ATP binding site, protein family[12], Serine/threonine-protein kinase, active site, protein family[13]
  • Has part(s): RGS domain[14], AGC-kinase, C-terminal[15], pleckstrin homology domain[16], protein kinase, ATP binding site[17], protein kinase domain[18], serine/threonine-protein kinase, active site[19]
  • Molecular function: G protein-coupled receptor kinase activity[20], ATP binding[21], transferase activity[22], protein kinase activity[23], nucleotide binding[24], protein serine/threonine kinase activity[25], kinase activity[26], beta-adrenergic receptor kinase activity[27]
  • Cell component: plasma membrane[28], cytosol[29]
  • Biological process: protein phosphorylation[30], receptor internalization[31], phosphorylation[32], signal transduction[33], G protein-coupled receptor signaling pathway[34]
  • Encoded by: GRK3[35]
  • Found in taxon: Homo sapiens[36]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . wikidata.org.
  10. [12] ↑ . wikidata.org.
  11. [13] ↑ . wikidata.org.
  12. [14] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Molecular cloning, functional expression and mRNA analysis of human beta-adrenergic receptor kinase 2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . Molecular cloning, functional expression and mRNA analysis of human beta-adrenergic receptor kinase 2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . UniProt. Retrieved . wikidata.org.
  34. [36] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). G protein-coupled receptor kinase 3. Retrieved May 3, 2026, from https://4ort.xyz/entity/g-protein-coupled-receptor-kinase-3
MLA “G protein-coupled receptor kinase 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/g-protein-coupled-receptor-kinase-3.
BibTeX @misc{4ortxyz_g-protein-coupled-receptor-kinase-3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{G protein-coupled receptor kinase 3}}, year = {2026}, url = {https://4ort.xyz/entity/g-protein-coupled-receptor-kinase-3}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Found in taxon → Homo sapiens
    Physically interacts with → balanol
    Wikidata description → mammalian protein found in Homo sapiens
    Mesh tree code → D08.811.913.696.620.682.700.364.049.300, D12.776.476.563.364.049.300
    + 14 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 2.7.11.15, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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