FURIN

protein-coding gene in the species Homo sapiens
Gene gene Q14916427
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FURIN

Summary

FURIN is a gene[1]. FURIN ranks in the top 0.88% of gene entities by monthly Wikipedia readership (177 views/month, #48 of 5,469).[2]

Key Facts

  • FURIN's instance of is recorded as gene[3].
  • FURIN is a type of protein-coding gene[4].
  • FURIN's Commons category is recorded as Furin[5].
  • FURIN's HomoloGene ID is recorded as 1930[6].
  • FURIN's genomic start is recorded as 91411822[7].
  • FURIN's genomic start is recorded as 90868588[8].
  • FURIN's genomic end is recorded as 90883458[9].
  • FURIN's genomic end is recorded as 91426688[10].
  • FURIN's molecular function is recorded as protease binding[11].
  • FURIN's molecular function is recorded as endopeptidase activity[12].
  • FURIN's molecular function is recorded as serine-type endopeptidase activity[13].
  • FURIN's molecular function is recorded as serine-type endopeptidase inhibitor activity[14].
  • FURIN's molecular function is recorded as protein binding[15].
  • FURIN's molecular function is recorded as peptidase activity[16].
  • FURIN's molecular function is recorded as serine-type peptidase activity[17].
  • FURIN's molecular function is recorded as hydrolase activity[18].
  • FURIN's molecular function is recorded as peptide binding[19].
  • FURIN's molecular function is recorded as metal ion binding[20].
  • FURIN's molecular function is recorded as nerve growth factor binding[21].
  • FURIN's cell component is recorded as Golgi membrane[22].
  • FURIN's cell component is recorded as extracellular space[23].
  • FURIN's cell component is recorded as endoplasmic reticulum[24].
  • FURIN's cell component is recorded as Golgi apparatus[25].
  • FURIN's cell component is recorded as Golgi lumen[26].
  • FURIN's cell component is recorded as trans-Golgi network[27].

Why It Matters

FURIN ranks in the top 0.88% of gene entities by monthly Wikipedia readership (177 views/month, #48 of 5,469).[2] FURIN has Wikipedia articles in 12 language editions, a strong signal of global cultural recognition.[28] FURIN is known by 8 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Ensembl Release 99. wikidata.org.
  2. [4] . Ensembl Release 87. wikidata.org.
  3. [5] . wikidata.org.
  4. [6] . Q20641742. Retrieved . wikidata.org.
  5. [7] . Ensembl Release 99. wikidata.org.
  6. [8] . Ensembl Release 99. wikidata.org.
  7. [9] . Ensembl Release 99. wikidata.org.
  8. [10] . Ensembl Release 99. wikidata.org.
  9. [11] . Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi network. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi network. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). FURIN. Retrieved May 3, 2026, from https://4ort.xyz/entity/furin
MLA “FURIN.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/furin.
BibTeX @misc{4ortxyz_furin_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{FURIN}}, year = {2026}, url = {https://4ort.xyz/entity/furin}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): FURIN — https://4ort.xyz/entity/furin (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/furin · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 13d ago · Mathieu Kappler · 2026-05-20 view diff on Wikidata ↗
    Biological process signal peptide processing, proteolysis, transforming growth factor beta receptor signaling pathway +25
    Subclass of
    Cell component Golgi membrane, extracellular space, endoplasmic reticulum +13
    Chromosome human chromosome 15
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||gsw */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/32527|batch #32527]]: human gene name and description in Alemannic"
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