Forkhead box A2

mammalian protein found in Rattus norvegicus

Protein protein Q28558433

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Forkhead box A2

Summary

Forkhead box A2 is a protein^[1].

Key Facts

Forkhead box A2's instance of is recorded as protein^[2].
Forkhead box A2's subclass of is recorded as protein^[3].
Forkhead box A2's UniProt protein ID is recorded as P32182^[4].
Forkhead box A2's part of is recorded as winged helix DNA-binding domain superfamily^[5].
Forkhead box A2's part of is recorded as Winged helix-like DNA-binding domain superfamily^[6].
Forkhead box A2's part of is recorded as Fork-head N-terminal domain, protein family^[7].
Forkhead box A2's part of is recorded as Forkhead box protein, C-terminal domain, protein family^[8].
Forkhead box A2's part of is recorded as Fork head domain, protein family^[9].
Forkhead box A2's part of is recorded as Fork head domain conserved site1, protein family^[10].
Forkhead box A2's part of is recorded as Fork head domain conserved site 2, protein family^[11].
Forkhead box A2's has part is recorded as Fork head domain^[12].
Forkhead box A2's has part is recorded as Fork head domain conserved site1^[13].
Forkhead box A2's has part is recorded as Forkhead box protein, C-terminal^[14].
Forkhead box A2's has part is recorded as Fork head domain conserved site 2^[15].
Forkhead box A2's has part is recorded as Fork-head N-terminal^[16].
Forkhead box A2's RefSeq protein ID is recorded as NP_036875^[17].
Forkhead box A2's RefSeq protein ID is recorded as XP_006235201^[18].
Forkhead box A2's RefSeq protein ID is recorded as NP_001386014^[19].
Forkhead box A2's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding^[20].
Forkhead box A2's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific^[21].
Forkhead box A2's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[22].
Forkhead box A2's molecular function is recorded as DNA binding^[23].
Forkhead box A2's molecular function is recorded as double-stranded DNA binding^[24].
Forkhead box A2's molecular function is recorded as DNA-binding transcription factor activity^[25].
Forkhead box A2's molecular function is recorded as protein binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of winged helix DNA-binding domain superfamily, Winged helix-like DNA-binding domain superfamily, Fork-head N-terminal domain, protein family, Forkhead box protein, C-terminal domain, protein family, Fork head domain, protein family, Fork head domain conserved site1, protein family, Fork head domain conserved site 2, protein family

Properties

Biological process cell fate specification, chromatin organization, regulation of transcription, DNA-templated, regulation of transcription by RNA polymerase II, multicellular organism development, adult locomotory behavior, anatomical structure morphogenesis, cell differentiation, response to insulin, positive regulation of embryonic development, positive regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II, dopaminergic neuron differentiation, primitive streak formation, positive regulation of gastrulation

Cell component nucleus, cytoplasm

Encoded by Foxa2

Found in taxon brown rat

Has part(s) Fork head domain, Fork head domain conserved site1, Forkhead box protein, C-terminal, Fork head domain conserved site 2, Fork-head N-terminal

Imported from wholeness_audit_2026-05-02

Molecular function RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA binding, double-stranded DNA binding, DNA-binding transcription factor activity, protein binding, transcription factor binding, kinase binding, protein domain specific binding, sequence-specific DNA binding, SMAD binding

External References (3)

Ensembl protein id ENSRNOP00000017742

Refseq protein id NP_036875, XP_006235201, NP_001386014

Uniprot protein id P32182

🏷️ Also known as

en Forkhead box A2 en forkhead box protein A2 en Foxa2 en hepatocyte nuclear factor 3-beta en HNF-3B en HNF-3-beta

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Forkhead box A2 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Forkhead box A2 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Forkhead box A2 — UniProt protein ID (P352): P32182. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Forkhead box A2 — part of (P361): winged helix DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Forkhead box A2 — part of (P361): Winged helix-like DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Forkhead box A2 — part of (P361): Fork-head N-terminal domain, protein family. wikidata.org.
[8] ↑ Forkhead box A2 — part of (P361): Forkhead box protein, C-terminal domain, protein family. wikidata.org.
[9] ↑ Forkhead box A2 — part of (P361): Fork head domain, protein family. wikidata.org.
[10] ↑ Forkhead box A2 — part of (P361): Fork head domain conserved site1, protein family. wikidata.org.
[11] ↑ Forkhead box A2 — part of (P361): Fork head domain conserved site 2, protein family. wikidata.org.
[12] ↑ Forkhead box A2 — has part(s) (P527): Fork head domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Forkhead box A2 — has part(s) (P527): Fork head domain conserved site1. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Forkhead box A2 — has part(s) (P527): Forkhead box protein, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Forkhead box A2 — has part(s) (P527): Fork head domain conserved site 2. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Forkhead box A2 — has part(s) (P527): Fork-head N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Forkhead box A2 — RefSeq protein ID (P637): NP_036875. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ Forkhead box A2 — RefSeq protein ID (P637): XP_006235201. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ Forkhead box A2 — RefSeq protein ID (P637): NP_001386014. Q20641742. Retrieved 2022-01-09. wikidata.org.
[20] ↑ Forkhead box A2 — molecular function (P680): RNA polymerase II cis-regulatory region sequence-specific DNA binding. Hepatocyte nuclear factor-4α interacts with other hepatocyte nuclear factors in regulating transthyretin gene expression. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Forkhead box A2 — molecular function (P680): DNA-binding transcription factor activity, RNA polymerase II-specific. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Forkhead box A2 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. Upstream region of rat serum albumin gene promoter contributes to promoter activity: presence of functional binding site for hepatocyte nuclear factor-3. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Forkhead box A2 — molecular function (P680): DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Forkhead box A2 — molecular function (P680): double-stranded DNA binding. Transcriptional regulation of the distal promoter of the rat pyruvate carboxylase gene by hepatocyte nuclear factor 3beta/Foxa2 and upstream stimulatory factors in insulinoma cells. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Forkhead box A2 — molecular function (P680): DNA-binding transcription factor activity. Transcriptional regulation of the distal promoter of the rat pyruvate carboxylase gene by hepatocyte nuclear factor 3beta/Foxa2 and upstream stimulatory factors in insulinoma cells. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Forkhead box A2 — molecular function (P680): protein binding. Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3beta. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Forkhead box A2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Forkhead box A2. Retrieved May 3, 2026, from https://4ort.xyz/entity/forkhead-box-a2-q28558433

MLA

“Forkhead box A2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/forkhead-box-a2-q28558433.

BibTeX

@misc{4ortxyz_forkhead-box-a2-q28558433_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Forkhead box A2}}, year = {2026}, url = {https://4ort.xyz/entity/forkhead-box-a2-q28558433}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Forkhead box A2 — https://4ort.xyz/entity/forkhead-box-a2-q28558433 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/forkhead-box-a2-q28558433 · Last refreshed: May 3, 2026