Forkhead box A1

mammalian protein found in Homo sapiens

Protein protein Q21107407

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Forkhead box A1

Summary

Forkhead box A1 is a protein^[1].

Key Facts

Forkhead box A1's instance of is recorded as protein^[2].
Forkhead box A1's UniProt protein ID is recorded as P55317^[3].
Forkhead box A1's part of is recorded as winged helix DNA-binding domain superfamily^[4].
Forkhead box A1's part of is recorded as Winged helix-like DNA-binding domain superfamily^[5].
Forkhead box A1's part of is recorded as Fork-head N-terminal domain, protein family^[6].
Forkhead box A1's part of is recorded as Forkhead box protein, C-terminal domain, protein family^[7].
Forkhead box A1's part of is recorded as Fork head domain, protein family^[8].
Forkhead box A1's part of is recorded as Fork head domain conserved site1, protein family^[9].
Forkhead box A1's part of is recorded as Fork head domain conserved site 2, protein family^[10].
Forkhead box A1's MeSH descriptor ID is recorded as D051541^[11].
Forkhead box A1's has part is recorded as Fork-head N-terminal^[12].
Forkhead box A1's has part is recorded as Forkhead box protein, C-terminal^[13].
Forkhead box A1's has part is recorded as Fork head domain^[14].
Forkhead box A1's has part is recorded as Fork head domain conserved site1^[15].
Forkhead box A1's has part is recorded as Fork head domain conserved site 2^[16].
Forkhead box A1's RefSeq protein ID is recorded as NP_004487^[17].
Forkhead box A1's RefSeq protein ID is recorded as XP_016876735^[18].
Forkhead box A1's MeSH tree code is recorded as D12.776.260.262.750^[19].
Forkhead box A1's MeSH tree code is recorded as D12.776.260.950.249.500^[20].
Forkhead box A1's MeSH tree code is recorded as D12.776.660.352.750^[21].
Forkhead box A1's MeSH tree code is recorded as D12.776.930.318.750^[22].
Forkhead box A1's MeSH tree code is recorded as D12.776.930.977.249.500^[23].
Forkhead box A1's molecular function is recorded as sequence-specific DNA binding^[24].
Forkhead box A1's molecular function is recorded as protein domain specific binding^[25].
Forkhead box A1's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[26].

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Quick Facts

Instance of protein

Part of winged helix DNA-binding domain superfamily, Winged helix-like DNA-binding domain superfamily, Fork-head N-terminal domain, protein family, Forkhead box protein, C-terminal domain, protein family, Fork head domain, protein family, Fork head domain conserved site1, protein family, Fork head domain conserved site 2, protein family

Properties

Biological process Notch signaling pathway, prostate gland stromal morphogenesis, dopaminergic neuron differentiation, positive regulation of intracellular estrogen receptor signaling pathway, response to estradiol, regulation of transcription, DNA-templated, lung morphogenesis, glucose homeostasis, positive regulation of smoothened signaling pathway, lung development, regulation of transcription by RNA polymerase II, neuron fate specification, anatomical structure formation involved in morphogenesis, positive regulation of mitotic cell cycle, positive regulation of DNA-binding transcription factor activity, negative regulation of transcription by RNA polymerase II, transcription by RNA polymerase II, tube morphogenesis, secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development, transcription, DNA-templated, regulation of cell cycle, multicellular organism development, prostate gland epithelium morphogenesis, connective tissue development, positive regulation of neuron differentiation, epithelial cell maturation involved in prostate gland development, regulation of gene expression, lung epithelial cell differentiation, dorsal/ventral neural tube patterning, epithelial-mesenchymal signaling involved in prostate gland development, epithelial tube branching involved in lung morphogenesis, respiratory basal cell differentiation, hormone metabolic process, alveolar secondary septum development, negative regulation of epithelial to mesenchymal transition, positive regulation of cell-cell adhesion mediated by cadherin, positive regulation of transcription by RNA polymerase II, chromatin remodeling, anatomical structure morphogenesis, positive regulation of apoptotic process, chromatin organization, regulation of transcription by RNA polymerase II, cell differentiation

Cell component microvillus, nucleus, fibrillar center, nucleoplasm, nucleus

Encoded by FOXA1

Found in taxon Homo sapiens

Has part(s) Fork-head N-terminal, Forkhead box protein, C-terminal, Fork head domain, Fork head domain conserved site1, Fork head domain conserved site 2

Imported from wholeness_audit_2026-05-02

Molecular function sequence-specific DNA binding, protein domain specific binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription activator activity, RNA polymerase II-specific, transcription factor binding, DNA-binding transcription factor activity, DNA binding, protein binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription activator activity, RNA polymerase II-specific

External References (6)

Ensembl protein id ENSP00000250448, ENSP00000451704

Mesh descriptor id D051541

Mesh tree code D12.776.260.262.750, D12.776.260.950.249.500, D12.776.660.352.750, D12.776.930.318.750, D12.776.930.977.249.500

Refseq protein id NP_004487, XP_016876735

Umls cui C0082859

Uniprot protein id P55317

🏷️ Also known as

en Forkhead box A1 en forkhead box protein A1 en FOXA1 en hepatocyte nuclear factor 3-alpha en HNF-3A en HNF-3-alpha en TCF-3A en transcription factor 3A

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Forkhead box A1 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Forkhead box A1 — UniProt protein ID (P352): P55317. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Forkhead box A1 — part of (P361): winged helix DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Forkhead box A1 — part of (P361): Winged helix-like DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Forkhead box A1 — part of (P361): Fork-head N-terminal domain, protein family. wikidata.org.
[7] ↑ Forkhead box A1 — part of (P361): Forkhead box protein, C-terminal domain, protein family. wikidata.org.
[8] ↑ Forkhead box A1 — part of (P361): Fork head domain, protein family. wikidata.org.
[9] ↑ Forkhead box A1 — part of (P361): Fork head domain conserved site1, protein family. wikidata.org.
[10] ↑ Forkhead box A1 — part of (P361): Fork head domain conserved site 2, protein family. wikidata.org.
[11] ↑ Forkhead box A1 — MeSH descriptor ID (P486): D051541. wikidata.org.
[12] ↑ Forkhead box A1 — has part(s) (P527): Fork-head N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Forkhead box A1 — has part(s) (P527): Forkhead box protein, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Forkhead box A1 — has part(s) (P527): Fork head domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Forkhead box A1 — has part(s) (P527): Fork head domain conserved site1. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Forkhead box A1 — has part(s) (P527): Fork head domain conserved site 2. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Forkhead box A1 — RefSeq protein ID (P637): NP_004487. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ Forkhead box A1 — RefSeq protein ID (P637): XP_016876735. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ Forkhead box A1 — MeSH tree code (P672): D12.776.260.262.750. wikidata.org.
[20] ↑ Forkhead box A1 — MeSH tree code (P672): D12.776.260.950.249.500. wikidata.org.
[21] ↑ Forkhead box A1 — MeSH tree code (P672): D12.776.660.352.750. wikidata.org.
[22] ↑ Forkhead box A1 — MeSH tree code (P672): D12.776.930.318.750. wikidata.org.
[23] ↑ Forkhead box A1 — MeSH tree code (P672): D12.776.930.977.249.500. wikidata.org.
[24] ↑ Forkhead box A1 — molecular function (P680): sequence-specific DNA binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Forkhead box A1 — molecular function (P680): protein domain specific binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Forkhead box A1 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Forkhead box A1 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Forkhead box A1. Retrieved May 3, 2026, from https://4ort.xyz/entity/forkhead-box-a1

MLA “Forkhead box A1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/forkhead-box-a1.

BibTeX

@misc{4ortxyz_forkhead-box-a1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Forkhead box A1}}, year = {2026}, url = {https://4ort.xyz/entity/forkhead-box-a1}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Forkhead box A1 — https://4ort.xyz/entity/forkhead-box-a1 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/forkhead-box-a1 · Last refreshed: May 3, 2026