FMS-like tyrosine kinase 1

mammalian protein found in Mus musculus

Protein protein Q21990307

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FMS-like tyrosine kinase 1

Summary

FMS-like tyrosine kinase 1 is a protein^[1].

Key Facts

FMS-like tyrosine kinase 1's instance of is recorded as protein^[2].
FMS-like tyrosine kinase 1's UniProt protein ID is recorded as P35969^[3].
FMS-like tyrosine kinase 1's part of is recorded as vascular endothelial growth factor receptor 1 (VEGFR1)^[4].
FMS-like tyrosine kinase 1's part of is recorded as Immunoglobulin-like fold^[5].
FMS-like tyrosine kinase 1's part of is recorded as Protein kinase-like domain superfamily^[6].
FMS-like tyrosine kinase 1's part of is recorded as Immunoglobulin-like domain superfamily^[7].
FMS-like tyrosine kinase 1's part of is recorded as membrane protein^[8].
FMS-like tyrosine kinase 1's part of is recorded as Immunoglobulin I-set, protein family^[9].
FMS-like tyrosine kinase 1's part of is recorded as Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family^[10].
FMS-like tyrosine kinase 1's part of is recorded as immunoglobulin subtype, protein family^[11].
FMS-like tyrosine kinase 1's part of is recorded as Immunoglobulin subtype 2, protein family^[12].
FMS-like tyrosine kinase 1's part of is recorded as Protein kinase domain, protein family^[13].
FMS-like tyrosine kinase 1's part of is recorded as immunoglobulin-like domain, protein family^[14].
FMS-like tyrosine kinase 1's part of is recorded as Protein kinase, ATP binding site, protein family^[15].
FMS-like tyrosine kinase 1's part of is recorded as Tyrosine-protein kinase, catalytic domain, protein family^[16].
FMS-like tyrosine kinase 1's part of is recorded as Tyrosine-protein kinase, receptor class III, conserved site, protein family^[17].
FMS-like tyrosine kinase 1's part of is recorded as Tyrosine-protein kinase, active site, protein family^[18].
FMS-like tyrosine kinase 1's has part is recorded as immunoglobulin subtype^[19].
FMS-like tyrosine kinase 1's has part is recorded as tyrosine-protein kinase, receptor class III, conserved site^[20].
FMS-like tyrosine kinase 1's has part is recorded as immunoglobulin subtype 2^[21].
FMS-like tyrosine kinase 1's has part is recorded as tyrosine-protein kinase, catalytic domain^[22].
FMS-like tyrosine kinase 1's has part is recorded as tyrosine-protein kinase, active site^[23].
FMS-like tyrosine kinase 1's has part is recorded as serine-threonine/tyrosine-protein kinase, catalytic domain^[24].
FMS-like tyrosine kinase 1's has part is recorded as immunoglobulin-like domain^[25].
FMS-like tyrosine kinase 1's has part is recorded as protein kinase, ATP binding site^[26].

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Quick Facts

Instance of protein

Part of vascular endothelial growth factor receptor 1 (VEGFR1), Immunoglobulin-like fold, Protein kinase-like domain superfamily, Immunoglobulin-like domain superfamily, membrane protein, Immunoglobulin I-set, protein family, Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family, immunoglobulin subtype, protein family, Immunoglobulin subtype 2, protein family, Protein kinase domain, protein family, immunoglobulin-like domain, protein family, Protein kinase, ATP binding site, protein family, Tyrosine-protein kinase, catalytic domain, protein family, Tyrosine-protein kinase, receptor class III, conserved site, protein family, Tyrosine-protein kinase, active site, protein family

Properties

Biological process post-embryonic camera-type eye morphogenesis, phosphorylation, positive regulation of phosphatidylinositol 3-kinase signaling, vascular endothelial growth factor receptor-1 signaling pathway, embryonic morphogenesis, sprouting angiogenesis, multicellular organism development, chemotaxis, monocyte chemotaxis, response to hypoxia, positive regulation of phospholipase C activity, cell differentiation, branching involved in blood vessel morphogenesis, blood vessel morphogenesis, positive regulation of phosphatidylinositol 3-kinase activity, protein phosphorylation, positive regulation of cell migration, positive regulation of vascular endothelial growth factor receptor signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, positive regulation of MAPK cascade, positive regulation of MAP kinase activity, cellular response to vascular endothelial growth factor stimulus, positive regulation of hematopoietic progenitor cell differentiation, positive regulation of angiogenesis, peptidyl-tyrosine phosphorylation, angiogenesis, vascular endothelial growth factor receptor signaling pathway, cell migration, protein autophosphorylation, vascular endothelial growth factor signaling pathway, negative regulation of vascular endothelial cell proliferation, negative regulation of signal transduction, cell differentiation, negative regulation of apoptotic process, positive regulation of ERK1 and ERK2 cascade, sprouting angiogenesis, transmembrane receptor protein tyrosine kinase signaling pathway, positive regulation of cell population proliferation, positive regulation of phosphatidylinositol 3-kinase signaling, cell migration, positive regulation of MAPK cascade, positive regulation of angiogenesis, vascular endothelial growth factor receptor signaling pathway

Cell component receptor complex, nucleus, endosome, integral component of membrane, membrane, integral component of plasma membrane, extracellular space, plasma membrane, actin cytoskeleton, cytoplasm, integral component of plasma membrane, receptor complex

Encoded by Flt1

Found in taxon house mouse

Has part(s) immunoglobulin subtype, tyrosine-protein kinase, receptor class III, conserved site, immunoglobulin subtype 2, tyrosine-protein kinase, catalytic domain, tyrosine-protein kinase, active site, serine-threonine/tyrosine-protein kinase, catalytic domain, immunoglobulin-like domain, protein kinase, ATP binding site, immunoglobulin I-set, protein kinase domain

Imported from wholeness_audit_2026-05-02

Molecular function nucleotide binding, transmembrane receptor protein tyrosine kinase activity, protein kinase activity, kinase activity, ATP binding, transferase activity, growth factor binding, identical protein binding, placental growth factor-activated receptor activity, protein tyrosine kinase activity, vascular endothelial growth factor-activated receptor activity, protein homodimerization activity, receptor tyrosine kinase, transmembrane signaling receptor activity, transmembrane receptor protein tyrosine kinase activity, vascular endothelial growth factor-activated receptor activity, protein binding, vascular endothelial growth factor binding

External References (3)

Ensembl protein id ENSMUSP00000031653, ENSMUSP00000106158

Refseq protein id NP_034358, XP_006504864, XP_006504865, XP_006504866, XP_011239302, NP_001350064, XP_036020680, XP_036020681

Uniprot protein id P35969

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ FMS-like tyrosine kinase 1 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ FMS-like tyrosine kinase 1 — UniProt protein ID (P352): P35969. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ FMS-like tyrosine kinase 1 — part of (P361): vascular endothelial growth factor receptor 1 (VEGFR1). InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ FMS-like tyrosine kinase 1 — part of (P361): Immunoglobulin-like fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ FMS-like tyrosine kinase 1 — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ FMS-like tyrosine kinase 1 — part of (P361): Immunoglobulin-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ FMS-like tyrosine kinase 1 — part of (P361): membrane protein. wikidata.org.
[9] ↑ FMS-like tyrosine kinase 1 — part of (P361): Immunoglobulin I-set, protein family. wikidata.org.
[10] ↑ FMS-like tyrosine kinase 1 — part of (P361): Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[11] ↑ FMS-like tyrosine kinase 1 — part of (P361): immunoglobulin subtype, protein family. wikidata.org.
[12] ↑ FMS-like tyrosine kinase 1 — part of (P361): Immunoglobulin subtype 2, protein family. wikidata.org.
[13] ↑ FMS-like tyrosine kinase 1 — part of (P361): Protein kinase domain, protein family. wikidata.org.
[14] ↑ FMS-like tyrosine kinase 1 — part of (P361): immunoglobulin-like domain, protein family. wikidata.org.
[15] ↑ FMS-like tyrosine kinase 1 — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[16] ↑ FMS-like tyrosine kinase 1 — part of (P361): Tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[17] ↑ FMS-like tyrosine kinase 1 — part of (P361): Tyrosine-protein kinase, receptor class III, conserved site, protein family. wikidata.org.
[18] ↑ FMS-like tyrosine kinase 1 — part of (P361): Tyrosine-protein kinase, active site, protein family. wikidata.org.
[19] ↑ FMS-like tyrosine kinase 1 — has part(s) (P527): immunoglobulin subtype. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ FMS-like tyrosine kinase 1 — has part(s) (P527): tyrosine-protein kinase, receptor class III, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ FMS-like tyrosine kinase 1 — has part(s) (P527): immunoglobulin subtype 2. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ FMS-like tyrosine kinase 1 — has part(s) (P527): tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ FMS-like tyrosine kinase 1 — has part(s) (P527): tyrosine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ FMS-like tyrosine kinase 1 — has part(s) (P527): serine-threonine/tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ FMS-like tyrosine kinase 1 — has part(s) (P527): immunoglobulin-like domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ FMS-like tyrosine kinase 1 — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ FMS-like tyrosine kinase 1 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

“FMS-like tyrosine kinase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/fms-like-tyrosine-kinase-1.

BibTeX

@misc{4ortxyz_fms-like-tyrosine-kinase-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{FMS-like tyrosine kinase 1}}, year = {2026}, url = {https://4ort.xyz/entity/fms-like-tyrosine-kinase-1}, note = {Accessed: 2026-05-03}}

LLM prompt

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