Fibroblast growth factor 19

mammalian protein found in Homo sapiens
Protein protein Q21172797
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Fibroblast growth factor 19

Summary

Fibroblast growth factor 19 is a protein[1].

Key Facts

  • Fibroblast growth factor 19's instance of is recorded as protein[2].
  • Fibroblast growth factor 19's subclass of is recorded as protein[3].
  • Fibroblast growth factor 19's UniProt protein ID is recorded as O95750[4].
  • Fibroblast growth factor 19's part of is recorded as Cytokine IL1/FGF[5].
  • Fibroblast growth factor 19's RefSeq protein ID is recorded as NP_005108[6].
  • Fibroblast growth factor 19's PDB structure ID is recorded as 1PWA[7].
  • Fibroblast growth factor 19's PDB structure ID is recorded as 2P23[8].
  • Fibroblast growth factor 19's molecular function is recorded as fibroblast growth factor receptor binding[9].
  • Fibroblast growth factor 19's molecular function is recorded as protein binding[10].
  • Fibroblast growth factor 19's molecular function is recorded as growth factor activity[11].
  • Fibroblast growth factor 19's molecular function is recorded as phosphatidylinositol-4,5-bisphosphate 3-kinase activity[12].
  • Fibroblast growth factor 19's molecular function is recorded as 1-phosphatidylinositol-3-kinase activity[13].
  • Fibroblast growth factor 19's cell component is recorded as extracellular region[14].
  • Fibroblast growth factor 19's cell component is recorded as intracellular anatomical structure[15].
  • Fibroblast growth factor 19's biological process is recorded as positive regulation of glucose import[16].
  • Fibroblast growth factor 19's biological process is recorded as positive regulation of protein phosphorylation[17].
  • Fibroblast growth factor 19's biological process is recorded as positive regulation of JNK cascade[18].
  • Fibroblast growth factor 19's biological process is recorded as negative regulation of gene expression[19].
  • Fibroblast growth factor 19's biological process is recorded as nervous system development[20].
  • Fibroblast growth factor 19's biological process is recorded as MAPK cascade[21].
  • Fibroblast growth factor 19's biological process is recorded as fibroblast growth factor receptor signaling pathway[22].
  • Fibroblast growth factor 19's biological process is recorded as positive regulation of cell population proliferation[23].
  • Fibroblast growth factor 19's biological process is recorded as positive regulation of ERK1 and ERK2 cascade[24].
  • Fibroblast growth factor 19's biological process is recorded as phosphatidylinositol phosphate biosynthetic process[25].
  • Fibroblast growth factor 19's biological process is recorded as phosphatidylinositol-3-phosphate biosynthetic process[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . Q905695. Retrieved . wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . Q20641742. Retrieved . wikidata.org.
  6. [7] . Q905695. Retrieved . wikidata.org.
  7. [8] . Q905695. Retrieved . wikidata.org.
  8. [9] . Liver-specific activities of FGF19 require Klotho beta. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Liver-specific activities of FGF19 require Klotho beta. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Fibroblast growth factor 19. Retrieved May 3, 2026, from https://4ort.xyz/entity/fibroblast-growth-factor-19
MLA “Fibroblast growth factor 19.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/fibroblast-growth-factor-19.
BibTeX @misc{4ortxyz_fibroblast-growth-factor-19_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Fibroblast growth factor 19}}, year = {2026}, url = {https://4ort.xyz/entity/fibroblast-growth-factor-19}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Fibroblast growth factor 19 — https://4ort.xyz/entity/fibroblast-growth-factor-19 (retrieved 2026-05-03)

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