Fas cell surface death receptor
mammalian protein found in Homo sapiens
Facts
9 properties- Instance of
- protein
- Part of
- fas receptor, Death-like domain superfamily, Fas receptor, death domain, protein family, Death domain, protein family, Fas receptor, N-terminal domain, protein family, TNFR/NGFR cysteine-rich region, protein family[2][3][4][5][6][7]
- Biological process
- renal system process, activation-induced cell death of T cells, tumor necrosis factor-mediated signaling pathway, T cell homeostasis, positive regulation of extrinsic apoptotic signaling pathway in absence of ligand, cellular response to mechanical stimulus, circadian rhythm, apoptotic signaling pathway, positive regulation of extrinsic apoptotic signaling pathway, regulation of extrinsic apoptotic signaling pathway via death domain receptors, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, spleen development, negative thymic T cell selection, regulation of lymphocyte differentiation, necroptotic signaling pathway, motor neuron apoptotic process, inflammatory response, regulation of myeloid cell differentiation, protein homooligomerization, response to toxic substance, B cell mediated immunity, neuron apoptotic process, positive regulation of protein homooligomerization, cellular response to lithium ion, positive regulation of lymphocyte apoptotic process, negative regulation of apoptotic process, immune response, gene expression, cellular response to hyperoxia, negative regulation of B cell activation, response to glucocorticoid, extrinsic apoptotic signaling pathway in absence of ligand, inflammatory cell apoptotic process, immunoglobulin production, signal transduction, hepatocyte apoptotic process, response to lipopolysaccharide, extrinsic apoptotic signaling pathway, regulation of apoptotic process, positive regulation of apoptotic process, regulation of cell population proliferation, negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, multicellular organism development, extrinsic apoptotic signaling pathway via death domain receptors, positive regulation of protein phosphorylation, regulation of stress-activated MAPK cascade, cellular response to amino acid starvation, Fas signaling pathway, positive regulation of apoptotic signaling pathway, positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, immune response, negative regulation of apoptotic process, protein-containing complex assembly, apoptotic signaling pathway, extrinsic apoptotic signaling pathway, necroptotic signaling pathway
- Cell component
- CD95 death-inducing signaling complex, membrane, extracellular region, cell surface, extracellular exosome, integral component of membrane, plasma membrane, integral component of plasma membrane, external side of plasma membrane, death-inducing signaling complex, membrane raft, cytosol, nuclear body, mitochondrion, cell surface, CD95 death-inducing signaling complex, extracellular exosome
- Encoded by
- FAS
- Found in taxon
- Homo sapiens
- Has part(s)
- death domain, TNFR/NGFR cysteine-rich region, Fas receptor, N-terminal, Fas receptor, death domain[8][9][10][11]
- Has parts
- death domain, TNFR/NGFR cysteine-rich region, Fas receptor, N-terminal, Fas receptor, death domain
- Molecular function
- kinase binding, protein binding, transmembrane signaling receptor activity, signal transducer activity, identical protein binding, tumor necrosis factor-activated receptor activity, tumor necrosis factor binding, calmodulin binding, signaling receptor activity
🏷️ Also known as
en Fas (TNF receptor superfamily, member 6)
en mutant tumor necrosis receptor superfamily member 6
en TNF receptor superfamily member 6
en tumor necrosis factor receptor superfamily member 6
en tumor necrosis factor receptor superfamily, member 6
en Apo-1 antigen
en APO-1 cell surface antigen
en apoptosis antigen 1
en apoptosis-mediating surface antigen FAS
en apoptosis signaling receptor FAS
en CD95 antigen
en FAS
en Fas AMA
en Fas cell surface death receptor
en FASLG receptor
cs Apo-1
cs CD95
cs FasR
cs Fas receptor
de Fas-Rezeptor
🔖 Identifiers · 7
- OpenAlex ID
- C3031857
- Ensembl protein ID
- ENSP00000347426, ENSP00000347979, ENSP00000349896, ENSP00000420975, ENSP00000422453, ENSP00000423755, ENSP00000424113, ENSP00000425159, ENSP00000345601, ENSP00000477997, ENSP00000498466
- Freebase ID
- /m/026cdwv
- Microsoft Academic ID (discontinued)
- 3031857
- RefSeq protein ID
- NP_000034, NP_001307548, NP_690610, NP_690611, XP_006717882, XP_011538066, XP_011538067, XP_011538068, XP_011538069
- UniProt protein ID
- P25445
🔗 Connections
Cell component 7
Biological process 6
Found in taxon 1
Instance of 1
Molecular function 1
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Summary
Fas cell surface death receptor is a protein[1].