F-box protein 7

mammalian protein found in Homo sapiens

Protein protein Q21101386

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Summary

F-box protein 7 is a protein^[1].

Key Facts

F-box protein 7's instance of is recorded as protein^[2].
F-box protein 7's UniProt protein ID is recorded as Q9Y3I1^[3].
F-box protein 7's part of is recorded as Ubiquitin-like domain superfamily^[4].
F-box protein 7's part of is recorded as F-box-like domain superfamily^[5].
F-box protein 7's part of is recorded as PI31 proteasome regulator, N-terminal domain, protein family^[6].
F-box protein 7's part of is recorded as F-box protein^[7].
F-box protein 7's has part is recorded as PI31 proteasome regulator, N-terminal^[8].
F-box protein 7's has part is recorded as F-box domain^[9].
F-box protein 7's RefSeq protein ID is recorded as NP_001028196^[10].
F-box protein 7's RefSeq protein ID is recorded as NP_001244919^[11].
F-box protein 7's RefSeq protein ID is recorded as NP_036311^[12].
F-box protein 7's RefSeq protein ID is recorded as XP_011528408^[13].
F-box protein 7's RefSeq protein ID is recorded as XP_024307975^[14].
F-box protein 7's PDB structure ID is recorded as 4L9C^[15].
F-box protein 7's PDB structure ID is recorded as 4L9H^[16].
F-box protein 7's molecular function is recorded as protein binding^[17].
F-box protein 7's molecular function is recorded as ubiquitin-protein transferase activity^[18].
F-box protein 7's molecular function is recorded as protein kinase binding^[19].
F-box protein 7's molecular function is recorded as ubiquitin protein ligase binding^[20].
F-box protein 7's molecular function is recorded as ubiquitin binding^[21].
F-box protein 7's molecular function is recorded as protein heterodimerization activity^[22].
F-box protein 7's molecular function is recorded as protein kinase binding^[23].
F-box protein 7's molecular function is recorded as ubiquitin-protein transferase activity^[24].
F-box protein 7's cell component is recorded as cytoplasm^[25].
F-box protein 7's cell component is recorded as ubiquitin ligase complex^[26].

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Quick Facts

Instance of protein

Part of Ubiquitin-like domain superfamily, F-box-like domain superfamily, PI31 proteasome regulator, N-terminal domain, protein family, F-box protein

Properties

Biological process negative regulation of G1/S transition of mitotic cell cycle, protein targeting to mitochondrion, negative regulation of lymphocyte differentiation, autophagy of mitochondrion, regulation of protein stability, negative regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of locomotion, protein polyubiquitination, regulation of neuron projection development, protein ubiquitination, negative regulation of oxidative stress-induced neuron death, negative regulation of neuron death, positive regulation of autophagy of mitochondrion, negative regulation of hydrogen peroxide-induced neuron death, post-translational protein modification, ubiquitin-dependent protein catabolic process, negative regulation of oxidative stress-induced neuron death, positive regulation of autophagy of mitochondrion

Cell component cytoplasm, ubiquitin ligase complex, mitochondrion, nucleus, cytosol, SCF ubiquitin ligase complex, glial cytoplasmic inclusion, classical Lewy body, Lewy neurite, Lewy body core, Lewy body corona, protein-containing complex

Encoded by FBXO7

Found in taxon Homo sapiens

Has part(s) PI31 proteasome regulator, N-terminal, F-box domain

Imported from wholeness_audit_2026-05-02

Molecular function protein binding, ubiquitin-protein transferase activity, protein kinase binding, ubiquitin protein ligase binding, ubiquitin binding, protein heterodimerization activity, protein kinase binding, ubiquitin-protein transferase activity

External References (4)

Ensembl protein id ENSP00000266087, ENSP00000380571, ENSP00000388547, ENSP00000395823, ENSP00000404388, ENSP00000406155

Pdb structure id 4L9C, 4L9H

Refseq protein id NP_001028196, NP_001244919, NP_036311, XP_011528408, XP_024307975

Uniprot protein id Q9Y3I1

🏷️ Also known as

en F-box only protein 7 en F-box protein 7 en FBXO7

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ F-box protein 7 — instance of (P31): protein. UniProt. Retrieved 2019-11-13. wikidata.org.
[3] ↑ F-box protein 7 — UniProt protein ID (P352): Q9Y3I1. UniProt. Retrieved 2019-11-13. wikidata.org.
[4] ↑ F-box protein 7 — part of (P361): Ubiquitin-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ F-box protein 7 — part of (P361): F-box-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ F-box protein 7 — part of (P361): PI31 proteasome regulator, N-terminal domain, protein family. wikidata.org.
[7] ↑ F-box protein 7 — part of (P361): F-box protein. wikidata.org.
[8] ↑ F-box protein 7 — has part(s) (P527): PI31 proteasome regulator, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ F-box protein 7 — has part(s) (P527): F-box domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ F-box protein 7 — RefSeq protein ID (P637): NP_001028196. Q20641742. Retrieved 2020-05-30. wikidata.org.
[11] ↑ F-box protein 7 — RefSeq protein ID (P637): NP_001244919. Q20641742. Retrieved 2020-05-30. wikidata.org.
[12] ↑ F-box protein 7 — RefSeq protein ID (P637): NP_036311. Q20641742. Retrieved 2020-05-30. wikidata.org.
[13] ↑ F-box protein 7 — RefSeq protein ID (P637): XP_011528408. Q20641742. Retrieved 2020-05-30. wikidata.org.
[14] ↑ F-box protein 7 — RefSeq protein ID (P637): XP_024307975. Q20641742. Retrieved 2020-05-30. wikidata.org.
[15] ↑ F-box protein 7 — PDB structure ID (P638): 4L9C. UniProt. Retrieved 2016-08-09. wikidata.org.
[16] ↑ F-box protein 7 — PDB structure ID (P638): 4L9H. UniProt. Retrieved 2016-08-09. wikidata.org.
[17] ↑ F-box protein 7 — molecular function (P680): protein binding. Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ F-box protein 7 — molecular function (P680): ubiquitin-protein transferase activity. GOA. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ F-box protein 7 — molecular function (P680): protein kinase binding. Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor. Retrieved 2018-02-27. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ F-box protein 7 — molecular function (P680): ubiquitin protein ligase binding. The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ F-box protein 7 — molecular function (P680): ubiquitin binding. FBXO7 Y52C polymorphism as a potential protective factor in Parkinson's disease. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ F-box protein 7 — molecular function (P680): protein heterodimerization activity. Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ F-box protein 7 — molecular function (P680): protein kinase binding. Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ F-box protein 7 — molecular function (P680): ubiquitin-protein transferase activity. Identification of a family of human F-box proteins. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ F-box protein 7 — cell component (P681): cytoplasm. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ F-box protein 7 — cell component (P681): ubiquitin ligase complex. Identification of a family of human F-box proteins. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ F-box protein 7 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). F-box protein 7. Retrieved May 3, 2026, from https://4ort.xyz/entity/f-box-protein-7-q21101386

MLA

“F-box protein 7.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/f-box-protein-7-q21101386.

BibTeX

@misc{4ortxyz_f-box-protein-7-q21101386_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{F-box protein 7}}, year = {2026}, url = {https://4ort.xyz/entity/f-box-protein-7-q21101386}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): F-box protein 7 — https://4ort.xyz/entity/f-box-protein-7-q21101386 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/f-box-protein-7-q21101386 · Last refreshed: May 3, 2026