Eukaryotic translation initiation factor 4E

mammalian protein found in Homo sapiens

Protein protein Q21172259

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Eukaryotic translation initiation factor 4E

Summary

Eukaryotic translation initiation factor 4E is a protein^[1].

Key Facts

Eukaryotic translation initiation factor 4E's instance of is recorded as protein^[2].
Eukaryotic translation initiation factor 4E's subclass of is recorded as protein^[3].
Eukaryotic translation initiation factor 4E's UniProt protein ID is recorded as P06730^[4].
Eukaryotic translation initiation factor 4E's part of is recorded as Translation Initiation factor eIF- 4e^[5].
Eukaryotic translation initiation factor 4E's part of is recorded as Translation Initiation factor eIF- 4e-like^[6].
Eukaryotic translation initiation factor 4E's part of is recorded as Eukaryotic translation initiation factor 4E (eIF-4E), conserved site, protein family^[7].
Eukaryotic translation initiation factor 4E's MeSH descriptor ID is recorded as C000632169^[8].
Eukaryotic translation initiation factor 4E's has part is recorded as Eukaryotic translation initiation factor 4E (eIF-4E), conserved site^[9].
Eukaryotic translation initiation factor 4E's RefSeq protein ID is recorded as NP_001124150^[10].
Eukaryotic translation initiation factor 4E's RefSeq protein ID is recorded as NP_001124151^[11].
Eukaryotic translation initiation factor 4E's RefSeq protein ID is recorded as NP_001317946^[12].
Eukaryotic translation initiation factor 4E's RefSeq protein ID is recorded as NP_001959^[13].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 1IPB^[14].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 1IPC^[15].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 1WKW^[16].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 2GPQ^[17].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 2V8W^[18].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 2V8X^[19].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 2V8Y^[20].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 2W97^[21].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 3AM7^[22].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 3TF2^[23].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 3U7X^[24].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 4AZA^[25].
Eukaryotic translation initiation factor 4E's PDB structure ID is recorded as 4BEA^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of Translation Initiation factor eIF- 4e, Translation Initiation factor eIF- 4e-like, Eukaryotic translation initiation factor 4E (eIF-4E), conserved site, protein family

Properties

Biological process nuclear-transcribed mRNA poly(A) tail shortening, negative regulation of translation, negative regulation of neuron differentiation, lung development, G1 phase, positive regulation of mitotic cell cycle, behavioral fear response, mRNA export from nucleus, stem cell population maintenance, translational initiation, viral process, regulation of translation, RNA export from nucleus, protein biosynthesis, negative regulation of autophagy, cellular response to dexamethasone stimulus, G1/S transition of mitotic cell cycle, regulation of translation at postsynapse, modulating synaptic transmission

Cell component cytoplasm, chromatoid body, RISC complex, P-body, mRNA cap binding complex, perinuclear region of cytoplasm, cytoplasmic stress granule, eukaryotic translation initiation factor 4F complex, extracellular exosome, cytosol, cytoplasmic ribonucleoprotein granule, eukaryotic translation initiation factor 4F complex, protein-containing complex, extracellular exosome, postsynapse, glutamatergic synapse, postsynaptic cytosol

Encoded by EIF4E

Found in taxon Homo sapiens

Has part(s) Eukaryotic translation initiation factor 4E (eIF-4E), conserved site

Imported from wholeness_audit_2026-05-02

Molecular function translation initiation factor activity, eukaryotic initiation factor 4G binding, protein binding, enzyme binding, RNA cap binding, RNA 7-methylguanosine cap binding, RNA binding, RNA 7-methylguanosine cap binding, RNA binding, translation initiation factor activity, translation regulator activity

External References (6)

Ensembl protein id ENSP00000280892, ENSP00000389624, ENSP00000425561, ENSP00000421287, ENSP00000423977, ENSP00000426602

Mesh descriptor id C000632169

Pdb structure id 1IPB, 1IPC, 1WKW, 2GPQ, 2V8W, 2V8X, 2V8Y, 2W97, 3AM7, 3TF2, 3U7X, 4AZA, 4BEA, 4DT6, 4DUM, 4TPW, 4TQB, 4TQC, 4UED, 5ABI

Refseq protein id NP_001124150, NP_001124151, NP_001317946, NP_001959

Umls cui C5197377

Uniprot protein id P06730

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Eukaryotic translation initiation factor 4E — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Eukaryotic translation initiation factor 4E — subclass of (P279): protein. Q905695. Retrieved 2016-12-01. wikidata.org.
[4] ↑ Eukaryotic translation initiation factor 4E — UniProt protein ID (P352): P06730. Q905695. Retrieved 2019-11-13. wikidata.org.
[5] ↑ Eukaryotic translation initiation factor 4E — part of (P361): Translation Initiation factor eIF- 4e. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Eukaryotic translation initiation factor 4E — part of (P361): Translation Initiation factor eIF- 4e-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Eukaryotic translation initiation factor 4E — part of (P361): Eukaryotic translation initiation factor 4E (eIF-4E), conserved site, protein family. wikidata.org.
[8] ↑ Eukaryotic translation initiation factor 4E — MeSH descriptor ID (P486): C000632169. wikidata.org.
[9] ↑ Eukaryotic translation initiation factor 4E — has part(s) (P527): Eukaryotic translation initiation factor 4E (eIF-4E), conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Eukaryotic translation initiation factor 4E — RefSeq protein ID (P637): NP_001124150. Q20641742. Retrieved 2020-05-30. wikidata.org.
[11] ↑ Eukaryotic translation initiation factor 4E — RefSeq protein ID (P637): NP_001124151. Q20641742. Retrieved 2020-05-30. wikidata.org.
[12] ↑ Eukaryotic translation initiation factor 4E — RefSeq protein ID (P637): NP_001317946. Q20641742. Retrieved 2020-05-30. wikidata.org.
[13] ↑ Eukaryotic translation initiation factor 4E — RefSeq protein ID (P637): NP_001959. Q20641742. Retrieved 2020-05-30. wikidata.org.
[14] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 1IPB. Q905695. Retrieved 2016-08-09. wikidata.org.
[15] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 1IPC. Q905695. Retrieved 2016-08-09. wikidata.org.
[16] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 1WKW. Q905695. Retrieved 2016-08-09. wikidata.org.
[17] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 2GPQ. Q905695. Retrieved 2016-08-09. wikidata.org.
[18] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 2V8W. Q905695. Retrieved 2016-08-09. wikidata.org.
[19] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 2V8X. Q905695. Retrieved 2016-08-09. wikidata.org.
[20] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 2V8Y. Q905695. Retrieved 2016-08-09. wikidata.org.
[21] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 2W97. Q905695. Retrieved 2016-08-09. wikidata.org.
[22] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 3AM7. Q905695. Retrieved 2016-08-09. wikidata.org.
[23] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 3TF2. Q905695. Retrieved 2016-08-09. wikidata.org.
[24] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 3U7X. Q905695. Retrieved 2016-08-09. wikidata.org.
[25] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 4AZA. Q905695. Retrieved 2016-08-09. wikidata.org.
[26] ↑ Eukaryotic translation initiation factor 4E — PDB structure ID (P638): 4BEA. Q905695. Retrieved 2016-08-09. wikidata.org.

Class ancestry

[1] ↑ Eukaryotic translation initiation factor 4E is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Eukaryotic translation initiation factor 4E. Retrieved May 3, 2026, from https://4ort.xyz/entity/eukaryotic-translation-initiation-factor-4e-q21172259

MLA

“Eukaryotic translation initiation factor 4E.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/eukaryotic-translation-initiation-factor-4e-q21172259.

BibTeX

@misc{4ortxyz_eukaryotic-translation-initiation-factor-4e-q21172259_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Eukaryotic translation initiation factor 4E}}, year = {2026}, url = {https://4ort.xyz/entity/eukaryotic-translation-initiation-factor-4e-q21172259}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Eukaryotic translation initiation factor 4E — https://4ort.xyz/entity/eukaryotic-translation-initiation-factor-4e-q21172259 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/eukaryotic-translation-initiation-factor-4e-q21172259 · Last refreshed: May 3, 2026