Eukaryotic translation initiation factor 4A3

mammalian protein found in Homo sapiens
Protein protein Q21131475
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Summary

Eukaryotic translation initiation factor 4A3 is a protein[1]. It is known by 15 alternative names across languages and contexts.[2]

Key Facts

  • Part of: P-loop containing nucleoside triphosphate hydrolase[3], P-P-bond-hydrolysis-driven transporter[4], Helicase superfamily 1/2, ATP-binding domain, protein family[5], Helicase, C-terminal domain, protein family[6], DEAD/DEAH box helicase[7], RNA helicase, DEAD-box type, Q motif, protein family[8], ATP-dependent RNA helicase DEAD-box, conserved site, protein family[9]
  • Has part(s): RNA helicase, DEAD-box type, Q motif[10], Helicase superfamily 1/2, ATP-binding domain[11], DEAD/DEAH box helicase domain[12], ATP-dependent RNA helicase DEAD-box, conserved site[13], Helicase, C-terminal[14]
  • Molecular function: nucleotide binding[15], selenocysteine insertion sequence binding[16], helicase activity[17], poly(A) binding[18], RNA stem-loop binding[19], protein binding[20], nucleic acid binding[21], ribonucleoprotein complex binding[22], hydrolase activity[23], ATP binding[24], mRNA binding[25], RNA binding[26], translation regulator activity[27]
  • Cell component: cytoplasm[28], cytosol[29], nuclear speck[30], catalytic step 2 spliceosome[31], membrane[32], exon-exon junction complex[33], soma[34], dendrite[35], spliceosomal complex[36], nucleus[37], nucleoplasm[38], nucleolus[39], glutamatergic synapse[40], postsynaptic cytosol[41]
  • Biological process: nuclear-transcribed mRNA poly(A) tail shortening[42], mRNA transport[43], negative regulation of translation[44], associative learning[45], response to organic cyclic compound[46], regulation of mRNA binding[47], mRNA processing[48], positive regulation of translation[49], negative regulation of gene expression[50], negative regulation of excitatory postsynaptic potential[51], cellular response to brain-derived neurotrophic factor stimulus[52], cellular response to selenite ion[53], exploration behavior[54], RNA secondary structure unwinding[55]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . Retrieved . wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . wikidata.org.
  8. [10] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . Defining the membrane proteome of NK cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  34. [36] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  35. [37] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  36. [38] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  37. [39] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  38. [40] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  39. [41] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  40. [42] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  41. [43] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  42. [44] ↑ . Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  43. [45] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  44. [46] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  45. [47] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  46. [48] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  47. [49] ↑ . SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  48. [50] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  49. [51] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  50. [52] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  51. [53] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  52. [54] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  53. [55] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Eukaryotic translation initiation factor 4A3. Retrieved May 3, 2026, from https://4ort.xyz/entity/eukaryotic-translation-initiation-factor-4a3-q21131475
MLA “Eukaryotic translation initiation factor 4A3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/eukaryotic-translation-initiation-factor-4a3-q21131475.
BibTeX @misc{4ortxyz_eukaryotic-translation-initiation-factor-4a3-q21131475_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Eukaryotic translation initiation factor 4A3}}, year = {2026}, url = {https://4ort.xyz/entity/eukaryotic-translation-initiation-factor-4a3-q21131475}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → EIF4A3
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → nucleotide binding, selenocysteine insertion sequence binding, helicase activity +11
    + 12 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 3.6.4.13, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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