Epidermal growth factor

mammalian protein found in Mus musculus

Protein protein Q14864699

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Epidermal growth factor

Summary

Epidermal growth factor is a protein^[1].

Key Facts

Epidermal growth factor's instance of is recorded as protein^[2].
Epidermal growth factor's UniProt protein ID is recorded as P01132^[3].
Epidermal growth factor's part of is recorded as Six-bladed beta-propeller, TolB-like^[4].
Epidermal growth factor's part of is recorded as Pro-epidermal growth factor^[5].
Epidermal growth factor's part of is recorded as Growth factor receptor cysteine-rich domain superfamily^[6].
Epidermal growth factor's part of is recorded as membrane protein^[7].
Epidermal growth factor's part of is recorded as EGF-like calcium-binding domain, protein family^[8].
Epidermal growth factor's part of is recorded as EGF-like domain, protein family^[9].
Epidermal growth factor's part of is recorded as EGF-like, conserved site, protein family^[10].
Epidermal growth factor's part of is recorded as LDLR class B repeat, protein family^[11].
Epidermal growth factor's part of is recorded as EGF-like calcium-binding, conserved site, protein family^[12].
Epidermal growth factor's has part is recorded as EGF-like calcium-binding, conserved site^[13].
Epidermal growth factor's has part is recorded as EGF-like calcium-binding domain^[14].
Epidermal growth factor's has part is recorded as LDLR class B repeat^[15].
Epidermal growth factor's has part is recorded as EGF-like, conserved site^[16].
Epidermal growth factor's has part is recorded as EGF-type aspartate/asparagine hydroxylation site^[17].
Epidermal growth factor's has part is recorded as EGF-like domain^[18].
Epidermal growth factor's RefSeq protein ID is recorded as NP_001297666^[19].
Epidermal growth factor's RefSeq protein ID is recorded as NP_001316523^[20].
Epidermal growth factor's RefSeq protein ID is recorded as NP_034243^[21].
Epidermal growth factor's RefSeq protein ID is recorded as XP_006501053^[22].
Epidermal growth factor's RefSeq protein ID is recorded as XP_011238312^[23].
Epidermal growth factor's RefSeq protein ID is recorded as XP_011238313^[24].
Epidermal growth factor's PDB structure ID is recorded as 1A3P^[25].
Epidermal growth factor's PDB structure ID is recorded as 1EGF^[26].

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Quick Facts

Instance of protein

Part of Six-bladed beta-propeller, TolB-like, Pro-epidermal growth factor, Growth factor receptor cysteine-rich domain superfamily, membrane protein, EGF-like calcium-binding domain, protein family, EGF-like domain, protein family, EGF-like, conserved site, protein family, LDLR class B repeat, protein family, EGF-like calcium-binding, conserved site, protein family

Properties

Biological process positive regulation of epidermal growth factor-activated receptor activity, regulation of protein transport, positive regulation of MAP kinase activity, regulation of protein localization to cell surface, ERK1 and ERK2 cascade, regulation of calcium ion import, mammary gland alveolus development, positive regulation of transcription, DNA-templated, negative regulation of secretion, positive regulation of hyaluronan biosynthetic process, positive regulation of peptidyl-threonine phosphorylation, positive regulation of ubiquitin-dependent protein catabolic process, angiogenesis, Wnt signaling pathway involved in dorsal/ventral axis specification, positive regulation of cell population proliferation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of cerebellar granule cell precursor proliferation, canonical Wnt signaling pathway, negative regulation of cholesterol efflux, peptidyl-tyrosine phosphorylation, positive regulation of DNA binding, positive regulation of phosphorylation, positive regulation of mitotic nuclear division, branching morphogenesis of an epithelial tube, regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein tyrosine kinase activity, positive regulation of receptor internalization, embryonic retina morphogenesis in camera-type eye, positive regulation of gene expression, positive regulation of cell migration, regulation of receptor signaling pathway via JAK-STAT, positive regulation of canonical Wnt signaling pathway, epidermal growth factor receptor signaling pathway, positive regulation of fibroblast proliferation, regulation of protein secretion, positive regulation of DNA biosynthetic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of protein localization to early endosome, positive regulation of protein localization to early endosome

Cell component integral component of membrane, membrane, receptor complex, plasma membrane, extracellular region, extracellular exosome, intracellular anatomical structure, extracellular space, plasma membrane

Encoded by Egf

Found in taxon house mouse

Has part(s) EGF-like calcium-binding, conserved site, EGF-like calcium-binding domain, LDLR class B repeat, EGF-like, conserved site, EGF-type aspartate/asparagine hydroxylation site, EGF-like domain

Imported from wholeness_audit_2026-05-02

Molecular function calcium ion binding, Wnt-protein binding, protein binding, Wnt-activated receptor activity, growth factor activity, protein tyrosine kinase activity, epidermal growth factor receptor binding

External References (4)

Ensembl protein id ENSMUSP00000029653, ENSMUSP00000142497, ENSMUSP00000143075, ENSMUSP00000143108

Pdb structure id 1A3P, 1EGF, 1EPG, 1EPH, 1EPI, 1EPJ, 3EGF, 1GK5

Refseq protein id NP_001297666, NP_001316523, NP_034243, XP_006501053, XP_011238312, XP_011238313

Uniprot protein id P01132

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Epidermal growth factor — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Epidermal growth factor — UniProt protein ID (P352): P01132. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ Epidermal growth factor — part of (P361): Six-bladed beta-propeller, TolB-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Epidermal growth factor — part of (P361): Pro-epidermal growth factor. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Epidermal growth factor — part of (P361): Growth factor receptor cysteine-rich domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Epidermal growth factor — part of (P361): membrane protein. wikidata.org.
[8] ↑ Epidermal growth factor — part of (P361): EGF-like calcium-binding domain, protein family. wikidata.org.
[9] ↑ Epidermal growth factor — part of (P361): EGF-like domain, protein family. wikidata.org.
[10] ↑ Epidermal growth factor — part of (P361): EGF-like, conserved site, protein family. wikidata.org.
[11] ↑ Epidermal growth factor — part of (P361): LDLR class B repeat, protein family. wikidata.org.
[12] ↑ Epidermal growth factor — part of (P361): EGF-like calcium-binding, conserved site, protein family. wikidata.org.
[13] ↑ Epidermal growth factor — has part(s) (P527): EGF-like calcium-binding, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Epidermal growth factor — has part(s) (P527): EGF-like calcium-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Epidermal growth factor — has part(s) (P527): LDLR class B repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Epidermal growth factor — has part(s) (P527): EGF-like, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Epidermal growth factor — has part(s) (P527): EGF-type aspartate/asparagine hydroxylation site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Epidermal growth factor — has part(s) (P527): EGF-like domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Epidermal growth factor — RefSeq protein ID (P637): NP_001297666. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ Epidermal growth factor — RefSeq protein ID (P637): NP_001316523. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ Epidermal growth factor — RefSeq protein ID (P637): NP_034243. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Epidermal growth factor — RefSeq protein ID (P637): XP_006501053. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Epidermal growth factor — RefSeq protein ID (P637): XP_011238312. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Epidermal growth factor — RefSeq protein ID (P637): XP_011238313. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Epidermal growth factor — PDB structure ID (P638): 1A3P. Q905695. Retrieved 2016-08-09. wikidata.org.
[26] ↑ Epidermal growth factor — PDB structure ID (P638): 1EGF. Q905695. Retrieved 2016-08-09. wikidata.org.

Class ancestry

[1] ↑ Epidermal growth factor is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Epidermal growth factor. Retrieved May 3, 2026, from https://4ort.xyz/entity/epidermal-growth-factor-q14864699

MLA

“Epidermal growth factor.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/epidermal-growth-factor-q14864699.

BibTeX

@misc{4ortxyz_epidermal-growth-factor-q14864699_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Epidermal growth factor}}, year = {2026}, url = {https://4ort.xyz/entity/epidermal-growth-factor-q14864699}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Epidermal growth factor — https://4ort.xyz/entity/epidermal-growth-factor-q14864699 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/epidermal-growth-factor-q14864699 · Last refreshed: May 3, 2026