Ectonucleotide pyrophosphatase/phosphodiesterase 3
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Summary
Ectonucleotide pyrophosphatase/phosphodiesterase 3 is a protein[1]. It is known by 11 alternative names across languages and contexts.[2]
Key Facts
- Part of: Somatomedin B-like domain superfamily[3], Alkaline-phosphatase-like, core domain superfamily[4], Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase[5], Somatomedin B[6], Extracellular Endonuclease, subunit A, protein family[7], DNA/RNA non-specific endonuclease family[8]
- Has part(s): DNA/RNA non-specific endonuclease[9], Extracellular Endonuclease, subunit A[10], Somatomedin B domain[11]
- Molecular function: nucleoside-triphosphate diphosphatase activity[12], nucleotide diphosphatase activity[13], phosphodiesterase I activity[14], polysaccharide binding[15], metal ion binding[16], scavenger receptor activity[17], NADH pyrophosphatase activity[18], catalytic activity[19], nucleic acid binding[20], hydrolase activity[21], calcium ion binding[22], zinc ion binding[23]
- Cell component: integral component of membrane[24], membrane[25], integral component of plasma membrane[26], extracellular region[27], perinuclear region of cytoplasm[28], extracellular exosome[29], plasma membrane[30], external side of plasma membrane[31], apical plasma membrane[32]
- Biological process: nucleoside triphosphate catabolic process[33], receptor-mediated endocytosis[34], immune response[35], phosphate-containing compound metabolic process[36], metabolism[37], inorganic diphosphate transport[38], nucleic acid phosphodiester bond hydrolysis[39], basophil activation involved in immune response[40], pyrimidine nucleotide metabolic process[41], negative regulation of mast cell activation involved in immune response[42], ATP metabolic process[43], negative regulation of inflammatory response[44], negative regulation of mast cell proliferation[45], vesicle-mediated transport[46]
- Encoded by: ENPP3[47]
- Found in taxon: Homo sapiens[48]
- Exact match: https://identifiers.org/uniprot:O14638[49], http://purl.uniprot.org/uniprot/O14638[50], https://www.ncbi.nlm.nih.gov/protein/O14638[51]