E2F transcription factor 8

mammalian protein found in Homo sapiens
Protein protein Q21112258
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Summary

E2F transcription factor 8 is a protein[1].

Key Facts

  • E2F transcription factor 8's instance of is recorded as protein[2].
  • E2F transcription factor 8's UniProt protein ID is recorded as A0AVK6[3].
  • E2F transcription factor 8's part of is recorded as winged helix DNA-binding domain superfamily[4].
  • E2F transcription factor 8's part of is recorded as Winged helix-like DNA-binding domain superfamily[5].
  • E2F transcription factor 8's part of is recorded as E2F family[6].
  • E2F transcription factor 8's part of is recorded as E2F/DP family, winged-helix DNA-binding domain, protein family[7].
  • E2F transcription factor 8's has part is recorded as E2F/DP family, winged-helix DNA-binding domain[8].
  • E2F transcription factor 8's RefSeq protein ID is recorded as NP_001243300[9].
  • E2F transcription factor 8's RefSeq protein ID is recorded as NP_001243301[10].
  • E2F transcription factor 8's RefSeq protein ID is recorded as NP_078956[11].
  • E2F transcription factor 8's RefSeq protein ID is recorded as XP_011518669[12].
  • E2F transcription factor 8's PDB structure ID is recorded as 4YO2[13].
  • E2F transcription factor 8's molecular function is recorded as DNA binding[14].
  • E2F transcription factor 8's molecular function is recorded as protein homodimerization activity[15].
  • E2F transcription factor 8's molecular function is recorded as DNA-binding transcription factor activity[16].
  • E2F transcription factor 8's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding[17].
  • E2F transcription factor 8's molecular function is recorded as DNA-binding transcription repressor activity, RNA polymerase II-specific[18].
  • E2F transcription factor 8's molecular function is recorded as protein binding[19].
  • E2F transcription factor 8's molecular function is recorded as identical protein binding[20].
  • E2F transcription factor 8's molecular function is recorded as transcription corepressor activity[21].
  • E2F transcription factor 8's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific[22].
  • E2F transcription factor 8's molecular function is recorded as cis-regulatory region sequence-specific DNA binding[23].
  • E2F transcription factor 8's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific[24].
  • E2F transcription factor 8's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific[25].
  • E2F transcription factor 8's molecular function is recorded as DNA-binding transcription repressor activity, RNA polymerase II-specific[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . UniProt. Retrieved . wikidata.org.
  2. [3] ↑ . UniProt. Retrieved . wikidata.org.
  3. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] ↑ . wikidata.org.
  7. [8] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . Q20641742. Retrieved . wikidata.org.
  9. [10] ↑ . Q20641742. Retrieved . wikidata.org.
  10. [11] ↑ . Q20641742. Retrieved . wikidata.org.
  11. [12] ↑ . Q20641742. Retrieved . wikidata.org.
  12. [13] ↑ . UniProt. Retrieved . wikidata.org.
  13. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . A proteome-scale map of the human interactome network. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] ↑ . A census of human transcription factors: function, expression and evolution. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] ↑ . E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] ↑ . A census of human transcription factors: function, expression and evolution. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] ↑ . Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). E2F transcription factor 8. Retrieved May 3, 2026, from https://4ort.xyz/entity/e2f-transcription-factor-8-q21112258
MLA “E2F transcription factor 8.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/e2f-transcription-factor-8-q21112258.
BibTeX @misc{4ortxyz_e2f-transcription-factor-8-q21112258_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{E2F transcription factor 8}}, year = {2026}, url = {https://4ort.xyz/entity/e2f-transcription-factor-8-q21112258}, note = {Accessed: 2026-05-03}}
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