E2F transcription factor 7

mammalian protein found in Mus musculus

Protein protein Q21984214

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E2F transcription factor 7

Summary

E2F transcription factor 7 is a protein^[1].

Key Facts

E2F transcription factor 7's instance of is recorded as protein^[2].
E2F transcription factor 7's subclass of is recorded as protein^[3].
E2F transcription factor 7's UniProt protein ID is recorded as Q6S7F2^[4].
E2F transcription factor 7's part of is recorded as winged helix DNA-binding domain superfamily^[5].
E2F transcription factor 7's part of is recorded as Winged helix-like DNA-binding domain superfamily^[6].
E2F transcription factor 7's part of is recorded as E2F family^[7].
E2F transcription factor 7's part of is recorded as E2F/DP family, winged-helix DNA-binding domain, protein family^[8].
E2F transcription factor 7's has part is recorded as E2F/DP family, winged-helix DNA-binding domain^[9].
E2F transcription factor 7's RefSeq protein ID is recorded as NP_848724^[10].
E2F transcription factor 7's RefSeq protein ID is recorded as NP_001345489^[11].
E2F transcription factor 7's RefSeq protein ID is recorded as XP_036011784^[12].
E2F transcription factor 7's molecular function is recorded as DNA binding^[13].
E2F transcription factor 7's molecular function is recorded as RNA polymerase II transcription regulatory region sequence-specific DNA binding^[14].
E2F transcription factor 7's molecular function is recorded as transcription corepressor activity^[15].
E2F transcription factor 7's molecular function is recorded as DNA-binding transcription factor activity^[16].
E2F transcription factor 7's molecular function is recorded as DNA-binding transcription repressor activity, RNA polymerase II-specific^[17].
E2F transcription factor 7's molecular function is recorded as identical protein binding^[18].
E2F transcription factor 7's molecular function is recorded as protein binding^[19].
E2F transcription factor 7's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding^[20].
E2F transcription factor 7's molecular function is recorded as cis-regulatory region sequence-specific DNA binding^[21].
E2F transcription factor 7's molecular function is recorded as cis-regulatory region sequence-specific DNA binding^[22].
E2F transcription factor 7's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific^[23].
E2F transcription factor 7's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[24].
E2F transcription factor 7's molecular function is recorded as DNA-binding transcription repressor activity, RNA polymerase II-specific^[25].
E2F transcription factor 7's molecular function is recorded as transcription factor binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of winged helix DNA-binding domain superfamily, Winged helix-like DNA-binding domain superfamily, E2F family, E2F/DP family, winged-helix DNA-binding domain, protein family

Properties

Biological process trophoblast giant cell differentiation, regulation of transcription, DNA-templated, chorionic trophoblast cell differentiation, negative regulation of transcription involved in G1/S transition of mitotic cell cycle, placenta development, DNA damage response, signal transduction by p53 class mediator, hepatocyte differentiation, sprouting angiogenesis, negative regulation of transcription by RNA polymerase II, transcription, DNA-templated, cellular response to DNA damage stimulus, negative regulation of G1/S transition of mitotic cell cycle, cell cycle, negative regulation of cytokinesis, positive regulation of DNA endoreduplication, positive regulation of transcription by RNA polymerase II, negative regulation of cell population proliferation, negative regulation of transcription by RNA polymerase II, positive regulation of transcription by RNA polymerase II, regulation of cell cycle

Cell component transcription regulator complex, nucleus, nuclear speck, RNA polymerase II transcription regulator complex, nucleus

Encoded by E2f7

Found in taxon house mouse

Has part(s) E2F/DP family, winged-helix DNA-binding domain

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, transcription corepressor activity, DNA-binding transcription factor activity, DNA-binding transcription repressor activity, RNA polymerase II-specific, identical protein binding, protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, cis-regulatory region sequence-specific DNA binding, cis-regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, transcription factor binding, sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, DNA binding, DNA-binding transcription factor activity

External References (3)

Ensembl protein id ENSMUSP00000073453, ENSMUSP00000133494, ENSMUSP00000133801, ENSMUSP00000133813, ENSMUSP00000134039

Refseq protein id NP_848724, NP_001345489, XP_036011784

Uniprot protein id Q6S7F2

🏷️ Also known as

en E2f7 en E2F-7 en E2F transcription factor 7 en transcription factor E2F7

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ E2F transcription factor 7 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ E2F transcription factor 7 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ E2F transcription factor 7 — UniProt protein ID (P352): Q6S7F2. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ E2F transcription factor 7 — part of (P361): winged helix DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ E2F transcription factor 7 — part of (P361): Winged helix-like DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ E2F transcription factor 7 — part of (P361): E2F family. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ E2F transcription factor 7 — part of (P361): E2F/DP family, winged-helix DNA-binding domain, protein family. wikidata.org.
[9] ↑ E2F transcription factor 7 — has part(s) (P527): E2F/DP family, winged-helix DNA-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ E2F transcription factor 7 — RefSeq protein ID (P637): NP_848724. Q20641742. Retrieved 2022-03-20. wikidata.org.
[11] ↑ E2F transcription factor 7 — RefSeq protein ID (P637): NP_001345489. Q20641742. Retrieved 2022-03-20. wikidata.org.
[12] ↑ E2F transcription factor 7 — RefSeq protein ID (P637): XP_036011784. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ E2F transcription factor 7 — molecular function (P680): DNA binding. GOA. Retrieved 2018-11-07. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ E2F transcription factor 7 — molecular function (P680): RNA polymerase II transcription regulatory region sequence-specific DNA binding. Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ E2F transcription factor 7 — molecular function (P680): transcription corepressor activity. Atypical E2F repressors and activators coordinate placental development. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ E2F transcription factor 7 — molecular function (P680): DNA-binding transcription factor activity. GOA. Retrieved 2018-11-07. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ E2F transcription factor 7 — molecular function (P680): DNA-binding transcription repressor activity, RNA polymerase II-specific. Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ E2F transcription factor 7 — molecular function (P680): identical protein binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ E2F transcription factor 7 — molecular function (P680): protein binding. E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ E2F transcription factor 7 — molecular function (P680): RNA polymerase II cis-regulatory region sequence-specific DNA binding. E2F7 represses a network of oscillating cell cycle genes to control S-phase progression. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ E2F transcription factor 7 — molecular function (P680): cis-regulatory region sequence-specific DNA binding. GOA. Retrieved 2018-06-05. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ E2F transcription factor 7 — molecular function (P680): cis-regulatory region sequence-specific DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ E2F transcription factor 7 — molecular function (P680): DNA-binding transcription factor activity, RNA polymerase II-specific. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ E2F transcription factor 7 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ E2F transcription factor 7 — molecular function (P680): DNA-binding transcription repressor activity, RNA polymerase II-specific. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ E2F transcription factor 7 — molecular function (P680): transcription factor binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ E2F transcription factor 7 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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BibTeX

@misc{4ortxyz_e2f-transcription-factor-7_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{E2F transcription factor 7}}, year = {2026}, url = {https://4ort.xyz/entity/e2f-transcription-factor-7}, note = {Accessed: 2026-05-03}}

LLM prompt

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