E2F transcription factor 1 Dmel_CG6376

protein found in Drosophila melanogaster

Protein protein Q29810463

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Summary

E2F transcription factor 1 Dmel_CG6376 is a protein^[1].

Key Facts

E2F transcription factor 1 Dmel_CG6376's instance of is recorded as protein^[2].
E2F transcription factor 1 Dmel_CG6376's UniProt protein ID is recorded as Q27368^[3].
E2F transcription factor 1 Dmel_CG6376's part of is recorded as winged helix DNA-binding domain superfamily^[4].
E2F transcription factor 1 Dmel_CG6376's part of is recorded as Winged helix-like DNA-binding domain superfamily^[5].
E2F transcription factor 1 Dmel_CG6376's part of is recorded as E2F family^[6].
E2F transcription factor 1 Dmel_CG6376's part of is recorded as E2F-DP heterodimerization region^[7].
E2F transcription factor 1 Dmel_CG6376's part of is recorded as E2F/DP family, winged-helix DNA-binding domain, protein family^[8].
E2F transcription factor 1 Dmel_CG6376's part of is recorded as E2F transcription factor, CC-MB domain, protein family^[9].
E2F transcription factor 1 Dmel_CG6376's has part is recorded as E2F transcription factor, CC-MB domain^[10].
E2F transcription factor 1 Dmel_CG6376's has part is recorded as E2F/DP family, winged-helix DNA-binding domain^[11].
E2F transcription factor 1 Dmel_CG6376's RefSeq protein ID is recorded as NP_001262809^[12].
E2F transcription factor 1 Dmel_CG6376's RefSeq protein ID is recorded as NP_001287454^[13].
E2F transcription factor 1 Dmel_CG6376's RefSeq protein ID is recorded as NP_001287455^[14].
E2F transcription factor 1 Dmel_CG6376's RefSeq protein ID is recorded as NP_524437^[15].
E2F transcription factor 1 Dmel_CG6376's RefSeq protein ID is recorded as NP_732646^[16].
E2F transcription factor 1 Dmel_CG6376's RefSeq protein ID is recorded as NP_732647^[17].
E2F transcription factor 1 Dmel_CG6376's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific^[18].
E2F transcription factor 1 Dmel_CG6376's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[19].
E2F transcription factor 1 Dmel_CG6376's molecular function is recorded as DNA binding^[20].
E2F transcription factor 1 Dmel_CG6376's molecular function is recorded as DNA-binding transcription factor activity^[21].
E2F transcription factor 1 Dmel_CG6376's molecular function is recorded as protein binding^[22].
E2F transcription factor 1 Dmel_CG6376's molecular function is recorded as transcription factor binding^[23].
E2F transcription factor 1 Dmel_CG6376's molecular function is recorded as sequence-specific DNA binding^[24].
E2F transcription factor 1 Dmel_CG6376's molecular function is recorded as protein dimerization activity^[25].
E2F transcription factor 1 Dmel_CG6376's cell component is recorded as nucleus^[26].

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Quick Facts

Instance of protein

Part of winged helix DNA-binding domain superfamily, Winged helix-like DNA-binding domain superfamily, E2F family, E2F-DP heterodimerization region, E2F/DP family, winged-helix DNA-binding domain, protein family, E2F transcription factor, CC-MB domain, protein family

Properties

Biological process G1 phase, negative regulation of transcription by RNA polymerase II, transcription, DNA-templated, regulation of transcription, DNA-templated, transcription by RNA polymerase II, multicellular organism development, eggshell chorion gene amplification, ventral cord development, imaginal disc development, positive regulation of cell population proliferation, positive regulation of gene expression, regulation of glucose metabolic process, antimicrobial humoral response, larval lymph gland hemopoiesis, regulation of hemocyte proliferation, DNA endoreduplication, nurse cell apoptotic process, positive regulation of nurse cell apoptotic process, positive regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II, neuron development, dendrite morphogenesis, regulation of cell cycle, muscle tissue development, regulation of execution phase of apoptosis, positive regulation of TORC1 signaling

Cell component nucleus, nucleoplasm, transcription regulator complex, Rb-E2F complex

Encoded by E2f1

Found in taxon Drosophila melanogaster

Has part(s) E2F transcription factor, CC-MB domain, E2F/DP family, winged-helix DNA-binding domain

Imported from wholeness_audit_2026-05-02

Molecular function DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA binding, DNA-binding transcription factor activity, protein binding, transcription factor binding, sequence-specific DNA binding, protein dimerization activity

External References (3)

Ensembl protein id FBpp0306739, FBpp0083517, FBpp0083516, FBpp0311412, FBpp0311985, FBpp0083518

Refseq protein id NP_001262809, NP_001287454, NP_001287455, NP_524437, NP_732646, NP_732647

Uniprot protein id Q27368

🏷️ Also known as

en CG6376 gene product from transcript CG6376-RF en CG6376-PA en CG6376-PB en CG6376-PC en CG6376-PD en CG6376-PE en CG6376-PF en E2f1 en E2f1-PA en E2f1-PB en E2f1-PC en E2f1-PD en E2f1-PE en E2f1-PF en E2F transcription factor en E2F transcription factor 1 en E2F transcription factor 1 Dmel_CG6376 en E2-promoter binding factor

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ E2F transcription factor 1 Dmel_CG6376 — instance of (P31): protein. UniProt. Retrieved 2022-05-25. wikidata.org.
[3] ↑ E2F transcription factor 1 Dmel_CG6376 — UniProt protein ID (P352): Q27368. UniProt. Retrieved 2022-05-25. wikidata.org.
[4] ↑ E2F transcription factor 1 Dmel_CG6376 — part of (P361): winged helix DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ E2F transcription factor 1 Dmel_CG6376 — part of (P361): Winged helix-like DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ E2F transcription factor 1 Dmel_CG6376 — part of (P361): E2F family. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ E2F transcription factor 1 Dmel_CG6376 — part of (P361): E2F-DP heterodimerization region. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ E2F transcription factor 1 Dmel_CG6376 — part of (P361): E2F/DP family, winged-helix DNA-binding domain, protein family. wikidata.org.
[9] ↑ E2F transcription factor 1 Dmel_CG6376 — part of (P361): E2F transcription factor, CC-MB domain, protein family. wikidata.org.
[10] ↑ E2F transcription factor 1 Dmel_CG6376 — has part(s) (P527): E2F transcription factor, CC-MB domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ E2F transcription factor 1 Dmel_CG6376 — has part(s) (P527): E2F/DP family, winged-helix DNA-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ E2F transcription factor 1 Dmel_CG6376 — RefSeq protein ID (P637): NP_001262809. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ E2F transcription factor 1 Dmel_CG6376 — RefSeq protein ID (P637): NP_001287454. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ E2F transcription factor 1 Dmel_CG6376 — RefSeq protein ID (P637): NP_001287455. Q20641742. Retrieved 2022-03-20. wikidata.org.
[15] ↑ E2F transcription factor 1 Dmel_CG6376 — RefSeq protein ID (P637): NP_524437. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ E2F transcription factor 1 Dmel_CG6376 — RefSeq protein ID (P637): NP_732646. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ E2F transcription factor 1 Dmel_CG6376 — RefSeq protein ID (P637): NP_732647. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ E2F transcription factor 1 Dmel_CG6376 — molecular function (P680): DNA-binding transcription factor activity, RNA polymerase II-specific. DNA-binding and trans-activation properties of Drosophila E2F and DP proteins. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ E2F transcription factor 1 Dmel_CG6376 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ E2F transcription factor 1 Dmel_CG6376 — molecular function (P680): DNA binding. GOA. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ E2F transcription factor 1 Dmel_CG6376 — molecular function (P680): DNA-binding transcription factor activity. Functional properties of a Drosophila homolog of the E2F1 gene. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ E2F transcription factor 1 Dmel_CG6376 — molecular function (P680): protein binding. Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ E2F transcription factor 1 Dmel_CG6376 — molecular function (P680): transcription factor binding. DNA-binding and trans-activation properties of Drosophila E2F and DP proteins. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ E2F transcription factor 1 Dmel_CG6376 — molecular function (P680): sequence-specific DNA binding. dE2F2, a Novel E2F-Family Transcription Factor inDrosophila melanogaster. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ E2F transcription factor 1 Dmel_CG6376 — molecular function (P680): protein dimerization activity. GOA. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ E2F transcription factor 1 Dmel_CG6376 — cell component (P681): nucleus. GOA. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ E2F transcription factor 1 Dmel_CG6376 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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MLA

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BibTeX

@misc{4ortxyz_e2f-transcription-factor-1-dmel-cg6376_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{E2F transcription factor 1 Dmel_CG6376}}, year = {2026}, url = {https://4ort.xyz/entity/e2f-transcription-factor-1-dmel-cg6376}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): E2F transcription factor 1 Dmel_CG6376 — https://4ort.xyz/entity/e2f-transcription-factor-1-dmel-cg6376 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/e2f-transcription-factor-1-dmel-cg6376 · Last refreshed: May 3, 2026