Dysferlin
mammalian protein found in Homo sapiens
Facts
9 properties- Instance of
- protein
- Part of
- C2 domain superfamily, Dysferlin, synaptosomal vesicle fusion pore, Ferlin, C-terminal domain, protein family, Ferlin A-domain, protein family, C2 domain, protein family, Ferlin, second C2 domain, protein family, Ferlin, first C2 domain, protein family, FerIin domain, protein family, Ferlin, third C2 domain, protein family, Ferlin, sixth C2 domain, protein family, Ferlin, fifth C2 domain, protein family, Ferlin, fourth C2 domain, protein family, Peroxin/Ferlin domain, protein family, Ferlin B-domain, protein family[2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]
- Biological process
- muscle contraction, plasma membrane repair, vesicle fusion, angiogenesis, positive regulation of endothelial cell proliferation, monocyte activation involved in immune response, macrophage activation involved in immune response, glycerol metabolic process, negative regulation of gene expression, lipid storage, T-tubule organization, negative regulation of protein catabolic process, skeletal muscle tissue regeneration, fat cell differentiation, positive regulation of cell adhesion, negative regulation of phagocytosis, cellular response to osmotic stress, positive regulation of neutrophil chemotaxis, regulation of calcium ion import, negative regulation of high voltage-gated calcium channel activity, negative regulation of protein polyubiquitination
- Cell component
- integral component of membrane, endosome, late endosome, membrane, T-tubule, plasma membrane, endocytic vesicle, early endosome, sarcolemma, extracellular exosome, cytoplasmic vesicle membrane, cytoplasmic vesicle, lamellipodium, microtubule organizing center, nucleus, Golgi apparatus, microtubule, extracellular exosome, membrane microdomain
- Encoded by
- DYSF
- Found in taxon
- Homo sapiens
- Has part(s)
- FerIin domain, Ferlin B-domain, C2 domain, Ferlin A-domain, Ferlin, C-terminal domain, Peroxin/Ferlin domain, Ferlin, fifth C2 domain, Ferlin, second C2 domain, Ferlin, third C2 domain, Ferlin, fourth C2 domain, Ferlin, first C2 domain, Ferlin, sixth C2 domain[17][18][19][20][21][22][23][24]
- Imported from
- wholeness_audit_2026-05-02
- Molecular function
- calcium ion binding, metal ion binding, protein binding, calcium-dependent phospholipid binding, phospholipid binding, lipid binding, microtubule binding, alpha-tubulin binding
🏷️ Also known as
en DYSF
en Dysferlin
en dystrophy-associated fer-1-like 1
en Dystrophy-associated fer-1-like protein
en fer-1-like family member 1
en fer-1-like protein 1
en limb girdle muscular dystrophy 2B (autosomal recessive)
🔖 Identifiers · 6
- Ensembl protein ID
- ENSP00000258104, ENSP00000377678, ENSP00000386285, ENSP00000386512, ENSP00000386547, ENSP00000386617, ENSP00000386683, ENSP00000386881, ENSP00000387137, ENSP00000398305, ENSP00000407046
- KBpedia ID
- Dysferlin
- RefSeq protein ID
- NP_001123927, NP_001124448, NP_001124449, NP_001124450, NP_001124451, NP_001124452, NP_001124453, NP_001124454, NP_001124455, NP_001124456, NP_001124457, NP_001124458, NP_001124459, NP_003485, XP_005264641, XP_005264642
- Transporter Classification Database ID
- 1.F.1.2.1
- UniProt protein ID
- O75923
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Summary
Dysferlin is a protein[1].