Properties
Biological process
mitochondrial fragmentation involved in apoptotic process, regulation of ATP metabolic process, positive regulation of mitochondrial fission, endocytosis, cellular component disassembly involved in execution phase of apoptosis, mitochondrial fission, regulation of mitochondrion organization, regulation of protein oligomerization, regulation of peroxisome organization, membrane fusion, peroxisome fission, regulation of autophagy of mitochondrion, positive regulation of protein secretion, positive regulation of apoptotic process, protein localization to mitochondrion, positive regulation of release of cytochrome c from mitochondria, necroptosis, dynamin family protein polymerization involved in mitochondrial fission, heart contraction, mitochondrion morphogenesis, protein homotetramerization, mitochondrial membrane fission, positive regulation of intrinsic apoptotic signaling pathway, release of cytochrome c from mitochondria, positive regulation of GTPase activity, protein complex oligomerization, programmed cell death, mitochondrial fission, dynamin family protein polymerization involved in mitochondrial fission, mitochondrion organization, endoplasmic reticulum organization, apoptotic mitochondrial changes, negative regulation of mitochondrial fusion, regulation of mitochondrion organization, synaptic vesicle recycling via endosome, mitochondrial fragmentation involved in apoptotic process, intracellular distribution of mitochondria, synaptic vesicle endocytosis, protein homooligomerization, positive regulation of dendritic spine morphogenesis, membrane fusion, necroptosis, mitochondrion morphogenesis, cellular response to lipid, positive regulation of mitochondrial fission, mitochondrial membrane fission, cellular response to oxygen-glucose deprivation, execution phase of apoptosis, regulation of peroxisome organization, positive regulation of synaptic vesicle endocytosis, regulation of autophagy of mitochondrion, response to flavonoid, response to hypobaric hypoxia, positive regulation of synaptic vesicle exocytosis, calcium ion transport, mitochondrion organization, regulation of gene expression, regulation of ubiquitin protein ligase activity, rhythmic process
Cell component
cytoplasm, cytosol, Golgi apparatus, membrane, intracellular membrane-bounded organelle, microtubule cytoskeleton, peroxisome, synapse, synaptic vesicle membrane, mitochondrial outer membrane, cell junction, mitochondrion, brush border, perinuclear region of cytoplasm, clathrin-coated pit, microtubule, cytoplasmic vesicle, endomembrane system, endoplasmic reticulum membrane, Golgi membrane, cytoplasm, mitochondrion, endoplasmic reticulum, cytosol, membrane, mitochondrial membranes, protein-containing complex, perinuclear region of cytoplasm, postsynapse, presynaptic endocytic zone membrane, mitochondrion-derived vesicle, secretory vesicle
Ec enzyme number
3.6.5.5
Has part(s)
GTPase effector domain, Dynamin, GTPase domain, Dynamin GTPase effector, Dynamin central domain, Dynamin-type guanine nucleotide-binding (G) domain, Dynamin, GTPase region, conserved site
Molecular function
nucleotide binding, protein homodimerization activity, GTP binding, protein binding, GTPase activity, identical protein binding, hydrolase activity, ubiquitin protein ligase binding, lipid binding, GTPase activator activity, GTP-dependent protein binding, GTPase activity, microtubule binding, clathrin binding, protein homodimerization activity, protein-containing complex binding, BH2 domain binding
External References (5)
Ensembl protein id
ENSP00000266481, ENSP00000370388, ENSP00000404160, ENSP00000415131, ENSP00000448610, ENSP00000449089, ENSP00000450399, ENSP00000350948, ENSP00000390090, ENSP00000396030, ENSP00000447013, ENSP00000447788, ENSP00000447845, ENSP00000448105, ENSP00000448802, ENSP00000448936, ENSP00000450401
Pdb structure id
3W6N, 3W6O, 3W6P, 4BEJ, 4H1U, 4H1V
Refseq protein id
NP_001265392, NP_001265393, NP_001265394, NP_001265395, NP_001317309, NP_005681, NP_036192, NP_036193, XP_011518845, XP_011518846, XP_016874152, XP_016874153, XP_016874154
Transporter classification database id
1.N.6.1.2
Uniprot protein id
O00429