Dual specificity phosphatase 22

mammalian protein found in Homo sapiens
Protein protein Q21107235
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Summary

Dual specificity phosphatase 22 is a protein[1]. It is known by 13 alternative names across languages and contexts.[2]

Key Facts

  • Part of: Protein-tyrosine phosphatase-like[3], Tyrosine specific protein phosphatases domain, protein family[4], Dual specificity phosphatase[5], Dual specificity protein phosphatase domain, protein family[6]
  • Has part(s): Dual specificity protein phosphatase domain[7], Tyrosine specific protein phosphatases domain[8]
  • Molecular function: protein tyrosine phosphatase activity[9], phosphatase activity[10], phosphoprotein phosphatase activity[11], hydrolase activity[12], protein tyrosine/serine/threonine phosphatase activity[13], non-membrane spanning protein tyrosine phosphatase activity[14], protein tyrosine kinase binding[15]
  • Cell component: cytoplasm[16], nucleus[17], cytosol[18], plasma membrane[19], filamentous actin[20], leading edge of lamellipodium[21]
  • Biological process: multicellular organism development[22], negative regulation of T cell mediated immunity[23], protein dephosphorylation[24], peptidyl-tyrosine dephosphorylation[25], cell population proliferation[26], negative regulation of T cell activation[27], negative regulation of transcription by RNA polymerase II[28], transforming growth factor beta receptor signaling pathway[29], regulation of cell population proliferation[30], positive regulation of JNK cascade[31], negative regulation of T cell receptor signaling pathway[32], dephosphorylation[33], apoptotic process[34], negative regulation of cell migration[35]
  • Encoded by: DUSP22[36]
  • Found in taxon: Homo sapiens[37]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . Regulation of STAT3-mediated signaling by LMW-DSP2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  34. [36] ↑ . UniProt. Retrieved . wikidata.org.
  35. [37] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Dual specificity phosphatase 22. Retrieved May 3, 2026, from https://4ort.xyz/entity/dual-specificity-phosphatase-22-q21107235
MLA “Dual specificity phosphatase 22.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/dual-specificity-phosphatase-22-q21107235.
BibTeX @misc{4ortxyz_dual-specificity-phosphatase-22-q21107235_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Dual specificity phosphatase 22}}, year = {2026}, url = {https://4ort.xyz/entity/dual-specificity-phosphatase-22-q21107235}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 13w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → DUSP22
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → protein tyrosine phosphatase activity, phosphatase activity, phosphoprotein phosphatase activity +5
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 3.1.3.16, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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