dopamine beta-hydroxylase
mammalian protein found in Homo sapiens
Facts
10 properties- Instance of
- protein
- Part of
- PHM/PNGase F domain superfamily, Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily, Tyramine beta-hydroxylase/Dopamine beta-hydroxylase, Copper type II, ascorbate-dependent monooxygenase-like, C-terminal, Copper type II, ascorbate-dependent monooxygenase, N-terminal domain, protein family, DOMON domain, protein family, Copper type II ascorbate-dependent monooxygenase, C-terminal domain, protein family, Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site, protein family, Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site, protein family[2][3][4][5][6][7][8][9][10]
- Biological process
- response to amphetamine, chemical synaptic transmission, homoiothermy, leukocyte mediated immunity, visual learning, fear response, behavioral response to ethanol, locomotory behavior, regulation of extrinsic apoptotic signaling pathway, regulation of cell population proliferation, positive regulation of vasoconstriction, glucose homeostasis, maternal behavior, memory, leukocyte migration, response to pain, blood vessel remodeling, cytokine production, associative learning, catecholamine biosynthetic process, dopamine catabolic process, norepinephrine biosynthetic process, octopamine biosynthetic process, dopamine catabolic process, norepinephrine biosynthetic process, positive regulation of cold-induced thermogenesis[39][40][41][42][43][44][45][46][47][48][49][50][51][52]
- Cell component
- cytoplasm, transport vesicle membrane, integral component of membrane, chromaffin granule lumen, chromaffin granule membrane, cytoplasmic vesicle, membrane, extracellular region, extracellular space, secretory granule membrane, secretory granule lumen, intracellular membrane-bounded organelle, endoplasmic reticulum, microtubule organizing center, extracellular space, cytoplasm, secretory granule membrane[25][26][27][28][29][30][31][32][33][34][35][36][37][38]
- EC enzyme number
- 1.14.17.1[16]
- Found in taxon
- Homo sapiens
- Has part(s)
- Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site, Copper type II ascorbate-dependent monooxygenase, C-terminal, Copper type II, ascorbate-dependent monooxygenase, N-terminal, DOMON domain, Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site[11][12][13][14][15]
- Molecular function
- metal ion binding, monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen, L-ascorbic acid binding, catalytic activity, dopamine beta-monooxygenase activity, copper ion binding, dopamine beta-monooxygenase activity, copper ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen, dopamine beta-monooxygenase activity[17][18][19][20][21][22][23][24]
- Physically interacts with
- nepicastat[1]
🏷️ Also known as
en Dopamine beta-hydroxylase
en Dopamine beta-monooxygenase
en dopamine beta-hydroxylase (dopamine beta-monooxygenase)
en DBH
en dopamine beta-hydroxylase
ar بيتا-هيدروكسيلاز الدوبامين
de Dopamin-β-Hydroxylase
de Dopaminhydroxylase
es Dopamina beta-hidroxilasa
es Dopamina β-hidroxilasa
fi Dopamiini-beeta-hydroksylaasi
fr Dopamine bêta-hydroxylase
id Dopamin beta-hidroksilase
it Dopamina beta-monoossigenasi
ja ドーパミン-β-モノオキシゲナーゼ
ko 도파민 베타-하이드록실화효소
pt Dopamina beta-hidroxilase
sv Dopamin-beta-hydroxylas
sv Dopamin-β-hydroxylas
tr DBH
🔖 Identifiers · 12
- OpenAlex ID
- C203531881
- Image (Wikimedia Commons)
- 4zel.jpg ↗
- Ensembl protein ID
- ENSP00000376776, ENSP00000263611
- Exact match
- purl.uniprot.org
- Freebase ID
- /m/026zbk3
- MeSH descriptor ID
- D004299
- MeSH tree code
- D08.811.682.690.708.292
- Microsoft Academic ID (discontinued)
- 203531881
- PDB structure ID
- 4ZEL
- RefSeq protein ID
- NP_000778
- UMLS CUI
- C0013032
- UniProt protein ID
- P09172
🔗 Connections
Cell component 6
Biological process 2
← Physically interacts with 2
Found in taxon 1
Instance of 1
Molecular function 1
Physically interacts with 1
Press Enter · cited answer in seconds