DNA polymerase epsilon, catalytic subunit

mammalian protein found in Homo sapiens

Protein protein Q21117982

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DNA polymerase epsilon, catalytic subunit

Summary

DNA polymerase epsilon, catalytic subunit is a protein^[1].

Key Facts

DNA polymerase epsilon, catalytic subunit's instance of is recorded as protein^[2].
DNA polymerase epsilon, catalytic subunit's UniProt protein ID is recorded as Q07864^[3].
DNA polymerase epsilon, catalytic subunit's part of is recorded as Ribonuclease H superfamily^[4].
DNA polymerase epsilon, catalytic subunit's part of is recorded as Ribonuclease H-like superfamily^[5].
DNA polymerase epsilon, catalytic subunit's part of is recorded as DNA polymerase epsilon catalytic subunit^[6].
DNA polymerase epsilon, catalytic subunit's part of is recorded as DNA-directed DNA polymerase, family B, exonuclease domain, protein family^[7].
DNA polymerase epsilon, catalytic subunit's part of is recorded as DNA polymerase epsilon, catalytic subunit A, C-terminal domain, protein family^[8].
DNA polymerase epsilon, catalytic subunit's part of is recorded as DNA-directed DNA polymerase, family B, multifunctional domain, protein family^[9].
DNA polymerase epsilon, catalytic subunit's has part is recorded as DNA-directed DNA polymerase, family B, exonuclease domain^[10].
DNA polymerase epsilon, catalytic subunit's has part is recorded as DNA-directed DNA polymerase, family B, multifunctional domain^[11].
DNA polymerase epsilon, catalytic subunit's has part is recorded as DNA polymerase epsilon, catalytic subunit A, C-terminal^[12].
DNA polymerase epsilon, catalytic subunit's RefSeq protein ID is recorded as NP_006222^[13].
DNA polymerase epsilon, catalytic subunit's RefSeq protein ID is recorded as XP_011533097^[14].
DNA polymerase epsilon, catalytic subunit's RefSeq protein ID is recorded as XP_011533099^[15].
DNA polymerase epsilon, catalytic subunit's RefSeq protein ID is recorded as XP_011533101^[16].
DNA polymerase epsilon, catalytic subunit's RefSeq protein ID is recorded as XP_011533104^[17].
DNA polymerase epsilon, catalytic subunit's molecular function is recorded as transferase activity^[18].
DNA polymerase epsilon, catalytic subunit's molecular function is recorded as nucleotide binding^[19].
DNA polymerase epsilon, catalytic subunit's molecular function is recorded as DNA binding^[20].
DNA polymerase epsilon, catalytic subunit's molecular function is recorded as 4 iron, 4 sulfur cluster binding^[21].
DNA polymerase epsilon, catalytic subunit's molecular function is recorded as nucleotidyltransferase activity^[22].
DNA polymerase epsilon, catalytic subunit's molecular function is recorded as iron-sulfur cluster binding^[23].
DNA polymerase epsilon, catalytic subunit's molecular function is recorded as zinc ion binding^[24].
DNA polymerase epsilon, catalytic subunit's molecular function is recorded as chromatin binding^[25].
DNA polymerase epsilon, catalytic subunit's molecular function is recorded as metal ion binding^[26].

⭐ Popularity Graph

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Quick Facts

Instance of protein

Part of Ribonuclease H superfamily, Ribonuclease H-like superfamily, DNA polymerase epsilon catalytic subunit, DNA-directed DNA polymerase, family B, exonuclease domain, protein family, DNA polymerase epsilon, catalytic subunit A, C-terminal domain, protein family, DNA-directed DNA polymerase, family B, multifunctional domain, protein family

Properties

Biological process nucleotide-excision repair, DNA gap filling, DNA synthesis involved in DNA repair, DNA biosynthetic process, embryonic organ development, nucleic acid phosphodiester bond hydrolysis, cellular response to DNA damage stimulus, base-excision repair, gap-filling, DNA repair, DNA replication, leading strand elongation, DNA replication proofreading, G1/S transition of mitotic cell cycle, mitotic cell cycle, base-excision repair, gap-filling, nucleotide-excision repair, DNA gap filling, DNA replication initiation, telomere maintenance via semi-conservative replication

Cell component plasma membrane, nucleoplasm, nucleus, epsilon DNA polymerase complex, epsilon DNA polymerase complex

Encoded by POLE

Found in taxon Homo sapiens

Has part(s) DNA-directed DNA polymerase, family B, exonuclease domain, DNA-directed DNA polymerase, family B, multifunctional domain, DNA polymerase epsilon, catalytic subunit A, C-terminal

Imported from wholeness_audit_2026-05-02

Molecular function transferase activity, nucleotide binding, DNA binding, 4 iron, 4 sulfur cluster binding, nucleotidyltransferase activity, iron-sulfur cluster binding, zinc ion binding, chromatin binding, metal ion binding, nucleic acid binding, DNA-directed DNA polymerase activity, single-stranded DNA 3'-5' exodeoxyribonuclease activity, protein binding, DNA binding, DNA-directed DNA polymerase activity

External References (3)

Ensembl protein id ENSP00000322570, ENSP00000442578, ENSP00000445753, ENSP00000479927, ENSP00000480727, ENSP00000500921, ENSP00000500233, ENSP00000500279

Refseq protein id NP_006222, XP_011533097, XP_011533099, XP_011533101, XP_011533104

Uniprot protein id Q07864

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ DNA polymerase epsilon, catalytic subunit — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ DNA polymerase epsilon, catalytic subunit — UniProt protein ID (P352): Q07864. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ DNA polymerase epsilon, catalytic subunit — part of (P361): Ribonuclease H superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ DNA polymerase epsilon, catalytic subunit — part of (P361): Ribonuclease H-like superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ DNA polymerase epsilon, catalytic subunit — part of (P361): DNA polymerase epsilon catalytic subunit. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ DNA polymerase epsilon, catalytic subunit — part of (P361): DNA-directed DNA polymerase, family B, exonuclease domain, protein family. wikidata.org.
[8] ↑ DNA polymerase epsilon, catalytic subunit — part of (P361): DNA polymerase epsilon, catalytic subunit A, C-terminal domain, protein family. wikidata.org.
[9] ↑ DNA polymerase epsilon, catalytic subunit — part of (P361): DNA-directed DNA polymerase, family B, multifunctional domain, protein family. wikidata.org.
[10] ↑ DNA polymerase epsilon, catalytic subunit — has part(s) (P527): DNA-directed DNA polymerase, family B, exonuclease domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ DNA polymerase epsilon, catalytic subunit — has part(s) (P527): DNA-directed DNA polymerase, family B, multifunctional domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ DNA polymerase epsilon, catalytic subunit — has part(s) (P527): DNA polymerase epsilon, catalytic subunit A, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ DNA polymerase epsilon, catalytic subunit — RefSeq protein ID (P637): NP_006222. Q20641742. Retrieved 2020-05-30. wikidata.org.
[14] ↑ DNA polymerase epsilon, catalytic subunit — RefSeq protein ID (P637): XP_011533097. Q20641742. Retrieved 2020-05-30. wikidata.org.
[15] ↑ DNA polymerase epsilon, catalytic subunit — RefSeq protein ID (P637): XP_011533099. Q20641742. Retrieved 2020-05-30. wikidata.org.
[16] ↑ DNA polymerase epsilon, catalytic subunit — RefSeq protein ID (P637): XP_011533101. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ DNA polymerase epsilon, catalytic subunit — RefSeq protein ID (P637): XP_011533104. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ DNA polymerase epsilon, catalytic subunit — molecular function (P680): transferase activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ DNA polymerase epsilon, catalytic subunit — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ DNA polymerase epsilon, catalytic subunit — molecular function (P680): DNA binding. Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase epsilon. Retrieved 2018-06-05. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ DNA polymerase epsilon, catalytic subunit — molecular function (P680): 4 iron, 4 sulfur cluster binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ DNA polymerase epsilon, catalytic subunit — molecular function (P680): nucleotidyltransferase activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ DNA polymerase epsilon, catalytic subunit — molecular function (P680): iron-sulfur cluster binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ DNA polymerase epsilon, catalytic subunit — molecular function (P680): zinc ion binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ DNA polymerase epsilon, catalytic subunit — molecular function (P680): chromatin binding. Distinctive activities of DNA polymerases during human DNA replication. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ DNA polymerase epsilon, catalytic subunit — molecular function (P680): metal ion binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ DNA polymerase epsilon, catalytic subunit is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). DNA polymerase epsilon, catalytic subunit. Retrieved May 3, 2026, from https://4ort.xyz/entity/dna-polymerase-epsilon-catalytic-subunit

MLA

“DNA polymerase epsilon, catalytic subunit.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/dna-polymerase-epsilon-catalytic-subunit.

BibTeX

@misc{4ortxyz_dna-polymerase-epsilon-catalytic-subunit_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{DNA polymerase epsilon, catalytic subunit}}, year = {2026}, url = {https://4ort.xyz/entity/dna-polymerase-epsilon-catalytic-subunit}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): DNA polymerase epsilon, catalytic subunit — https://4ort.xyz/entity/dna-polymerase-epsilon-catalytic-subunit (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/dna-polymerase-epsilon-catalytic-subunit · Last refreshed: May 3, 2026